(Q37621008)

21 August 2017

1 reference

title

Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis (English)

1 reference

21 August 2017

0 references

1 reference

0 references

1 reference

Shirine Benhenda

1

1 reference

21 August 2017

Delphine Cougot

series ordinal

2

1 reference

21 August 2017

Marie-Annick Buendia

series ordinal

3

1 reference

21 August 2017

Christine Neuveut

series ordinal

4

1 reference

21 August 2017

publication date

1 January 2009

1 reference

Advances in Cancer Research

21 August 2017

published in

1 reference

21 August 2017

volume

103

1 reference

21 August 2017

page(s)

75-109

1 reference

A pivotal role of cyclic AMP-responsive element binding protein in tumor progression

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Dual effects of hepatitis B virus X protein on the regulation of cell-cycle control depending on the status of cellular p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Different regions of hepatitis B virus X protein are required for enhancement of bZip-mediated transactivation versus transrepression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein enhances the DNA binding potential and transcription efficacy of bZip transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The proapoptotic effect of hepatitis B virus HBx protein correlates with its transactivation activity in stably transfected cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The enigmatic X gene of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Calcium signaling by HBx protein in hepatitis B virus DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein does not influence essential steps of nucleotide excision repair effected by human liver extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

RNA interference targeting HBx suppresses tumor growth and enhances cisplatin chemosensitivity in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X gene induces p53-mediated programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Interaction of hepatitis B viral X protein and CCAAT/ enhancer-binding protein alpha synergistically activates the hepatitis B viral enhancer II/pregenomic promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B viral X protein overcomes inhibition of E2F1 activity by pRb on the human Rb gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Calcium ions affect the hepatitis B virus core assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion method

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Tumor eradication by hepatitis B virus X antigen-specific CD8+ T cells in xenografted nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in hepatitis B virus X antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein localizes to mitochondria in primary rat hepatocytes and modulates mitochondrial membrane potential

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein modulates apoptosis in primary rat hepatocytes by regulating both NF-kappaB and the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Assignment of disulphide bonds in the X protein (HBx) of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus pX targets TFIIB in transcription coactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Intracellular localization of the hepatitis B virus HBx protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Subcellular localisation of the X protein in HBV infected hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Altered proteolysis and global gene expression in hepatitis B virus X transgenic mouse liver

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HLA-A2 1 restricted peptides from the HBx antigen induce specific CTL responses in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Detection of the hepatitis B virus X protein (HBx) antigen and anti-HBx antibodies in cases of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein inhibits nucleotide excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Transcriptional regulation of the TATA-binding protein by Ras cellular signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Expression of DNA methyltransferase 1 is activated by hepatitis B virus X protein via a regulatory circuit involving the p16INK4a-cyclin D1-CDK 4/6-pRb-E2F1 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

X-gene product of hepatitis B virus induces apoptosis in liver cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Activated ras oncogene collaborates with HBx gene of hepatitis B virus to transform cells by suppressing HBx-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus core protein stimulates the proteasome-mediated degradation of viral X protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus x protein induces perinuclear mitochondrial clustering in microtubule- and Dynein-dependent manners

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Ubiquitin-dependent and -independent proteasomal degradation of hepatitis B virus X protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Src kinases involved in hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatocarcinogenesis in hepatitis viral infection: lessons from transgenic mouse studies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Compensatory apoptosis in preneoplastic liver of a transgenic mouse model for viral hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein up-regulates tumor necrosis factor alpha gene expression in hepatocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus HBx protein induces adherens junction disruption in a src-dependent manner.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBx protein of hepatitis B virus activates Jak1-STAT signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein interacts with a probable cellular DNA repair protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Phosphorylation of purified recombinant hepatitis B virus-X protein by mitogen-activated protein kinase and protein kinase C in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein differentially regulates cell cycle progression in X-transforming versus nontransforming hepatocyte (AML12) cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Dimerization of hepatitis B viral X protein synthesized in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Id-1 induces proteasome-dependent degradation of the HBX protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein interferes with cell viability through interaction with the p127-kDa UV-damaged DNA-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Geminin is partially localized to the centrosome and plays a role in proper centrosome duplication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus transactivator HBx causes elevation of diacylglycerol and activation of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein transactivates inducible nitric oxide synthase gene promoter through the proximal nuclear factor kappaB-binding site: evidence that cytoplasmic location of X protein is essential for gene transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

In vivo hierarchy of immunodominant and subdominant HLA-A*0201-restricted T-cell epitopes of HBx antigen of hepatitis B virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBXIP functions as a cofactor of survivin in apoptosis suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus replication is associated with an HBx-dependent mitochondrion-regulated increase in cytosolic calcium levels

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus DNA replication is coordinated by core protein serine phosphorylation and HBx expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Trans-activation of epidermal growth factor receptor gene by the hepatitis B virus X-gene product.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-associated hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Inhibition of hepatitis B virus by lentiviral vector delivered antisense RNA and hammerhead ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Cell cycle dysregulation by HTLV-I: role of the tax oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Subcellular localization and transcriptional repressor activity of HBx on p21(WAF1/Cip1) promoter is regulated by ERK-mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein protects against anti-Fas-mediated apoptosis in human liver cells by inducing NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Up-regulation of cyclin D1 by HBx is mediated by NF-kappaB2/BCL3 complex through kappaB site of cyclin D1 promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Tumor suppressor protein p53 induces degradation of the oncogenic protein HBx.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Cancer burden in the year 2000. The global picture

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Pro-apoptotic effect of the hepatitis B virus X gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus transactivator protein X interacts with the TATA-binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein colocalizes to mitochondria with a human voltage-dependent anion channel, HVDAC3, and alters its transmembrane potential

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein increases the Cdt1-to-geminin ratio inducing DNA re-replication and polyploidy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The protooncogene c-jun is transactivated by the X protein of hepatitis B virus and highly expressed in liver cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Review: hepatitis B virus X-gene product: a promiscuous transcriptional activator

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Expression and spectroscopic analysis of a mutant hepatitis B virus onco-protein HBx without cysteine residues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Interaction of the hepatitis B virus protein HBx with the human transcription regulatory protein p120E4F in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Induction of apoptosis by the transactivating domains of the hepatitis B virus X gene leads to suppression of oncogenic transformation of primary rat embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

In vitro tumorigenicity of hepatitis B virus DNA and HBx protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein inhibits transforming growth factor-beta -induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus-X protein recruits histone deacetylase 1 to repress insulin-like growth factor binding protein 3 transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Correct binding of viral X protein to UVDDB-p127 cellular protein is critical for efficient infection by hepatitis B viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Knockdown of damage-specific DNA binding protein 1 (DDB1) enhances the HBx-siRNA-mediated inhibition of HBV replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein differentially activates RAS-RAF-MAPK and JNK pathways in X-transforming versus non-transforming AML12 hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein activates the p38 mitogen-activated protein kinase pathway in dedifferentiated hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Biology of hepatitis B virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Functional analysis of a liver-specific enhancer of the hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Activation of protooncogene c-jun by the X protein of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Functional inactivation but not structural mutation of p53 causes liver cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Isolation and molecular characterization of hepatitis B virus X-protein from a baculovirus expression system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

A soluble form of the avian hepatitis B virus receptor. Biochemical characterization and functional analysis of the receptor ligand complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Early and frequent detection of HBxAg and/or anti-HBx in hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The hepatitis B virus X protein increases the cellular level of TATA-binding protein, which mediates transactivation of RNA polymerase III genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein induces RNA polymerase III-dependent gene transcription and increases cellular TATA-binding protein by activating the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Regulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepadna virus integration generates virus-cell cotranscripts carrying 3' truncated X genes in human and woodchuck liver tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Direct association and nuclear import of the hepatitis B virus X protein with the NF-kappaB inhibitor IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Interaction of hepatitis B viral oncoprotein with cellular target HBXIP dysregulates centrosome dynamics and mitotic spindle formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Distinctive gene expression profiles associated with Hepatitis B virus x protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

SAGE transcript profiles of normal primary human hepatocytes expressing oncogenic hepatitis B virus X protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein disrupts DNA interstrand crosslinking agent mitomycin C induced ATR dependent intra-S-phase checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Enhancement of hepatitis B virus replication by its X protein in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein enhances the transcriptional activity of the androgen receptor through c-Src and glycogen synthase kinase-3beta kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepadnaviral X Protein:Review of Recent Progress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Gene expression profiles of human liver cells mediated by hepatitis B virus X protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The value of hepatitis B x antigen as a prognostic marker in the development of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein interferes with cellular DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

In vivo activity of the hepatitis B virus core promoter: tissue specificity and temporal regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

High-level hepatitis B virus replication in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Recognition efficiency of the hepatitis B virus polyadenylation signals is tissue specific in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Overexpression of p53 protein is not directly related to hepatitis B x protein expression and is associated with neoplastic progression in hepatocellular carcinomas rather than hepatic preneoplasia.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Activation of class I major histocompatibility complex gene expression by hepatitis B virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2903004-8

7 January 2021

10.1016/S0065-230X(09)03004-8

Identifiers

DOI

1 reference

21 August 2017

1 reference