(Q44509761)

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Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway

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scholarly article

1 reference

Europe PubMed Central

3 December 2017

Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway (English)

1 reference

Europe PubMed Central

3 December 2017

0 references

Hepatitis B virus

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

9

object named as

Je Kyung Seong

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Europe PubMed Central

3 December 2017

author name string

Young-Gun Yoo

1

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Europe PubMed Central

3 December 2017

Seung Hyun Oh

2

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Europe PubMed Central

3 December 2017

Eun Sook Park

3

1 reference

Europe PubMed Central

3 December 2017

Hyeseong Cho

4

1 reference

Europe PubMed Central

3 December 2017

Naery Lee

5

1 reference

Europe PubMed Central

3 December 2017

Hyunsung Park

6

1 reference

Europe PubMed Central

3 December 2017

Dae Kyong Kim

7

1 reference

Europe PubMed Central

3 December 2017

Dae-Yeul Yu

8

1 reference

Europe PubMed Central

3 December 2017

Mi-Ock Lee

10

1 reference

Europe PubMed Central

3 December 2017

language of work or name

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publication date

10 July 2003

1 reference

Europe PubMed Central

3 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

3 December 2017

278

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Europe PubMed Central

3 December 2017

40

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Europe PubMed Central

3 December 2017

39076-39084

1 reference

Europe PubMed Central

3 December 2017

Hepatitis B virus-induced hepatocellular carcinoma: possible roles for HBx.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Vascular endothelial growth factor: its prognostic, predictive, and therapeutic implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

ERK activation upon hypoxia: involvement in HIF-1 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Insulin-like growth factor II (IGF-II) secreted from HepG2 human hepatocellular carcinoma cells shows angiogenic activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Effect of the hepatitis B virus HBx protein on integrin-mediated adhesion to and migration on extracellular matrix

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

The hepatitis B virus X protein (HBx) induces a migratory phenotype in a CD44-dependent manner: possible role of HBx in invasion and metastasis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Human hepatitis B virus X protein is a possible mediator of hypoxia-induced angiogenesis in hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Hepatitis B virus X protein induced expression of the Nur77 gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Fas/Fas ligand interaction in human colorectal hepatic metastases: A mechanism of hepatocyte destruction to facilitate local tumor invasion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Transcription. Oxygen sensing gets a second wind

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Enhanced expression of vascular endothelial growth factor (VEGF) plays a critical role in the tumor progression potential induced by simian virus 40 large T antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Increased proliferation activities of vascular endothelial cells and tumour cells in residual hepatocellular carcinoma following transcatheter arterial embolization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Oncogenes and tumor angiogenesis: the HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305101200

21 January 2018

Identifiers

10.1074/JBC.M305101200

1 reference

Europe PubMed Central

3 December 2017

1 reference

Europe PubMed Central

3 December 2017

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