(Q37630418)

21 August 2017

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title

Pharmacogenetics and pharmacoepigenetics of gemcitabine (English)

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21 August 2017

M Candelaria

1

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21 August 2017

E de la Cruz-Hernández

2

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21 August 2017

E Pérez-Cárdenas

3

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21 August 2017

C Trejo-Becerril

4

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21 August 2017

O Gutiérrez-Hernández

5

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21 August 2017

A Dueñas-González

6

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21 August 2017

publication date

10 November 2009

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21 August 2017

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21 August 2017

volume

27

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21 August 2017

issue

4

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21 August 2017

page(s)

1133-1143

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https://scigraph.springernature.com/pub.10.1007/s12032-009-9349-y

21 August 2017

exact match

0 references

cites work

Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12032-009-9349-Y

Roles of the EZH2 histone methyltransferase in cancer epigenetics

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12032-009-9349-Y

Purification and properties of cytidine deaminase from normal and leukemic granulocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12032-009-9349-Y

Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients

21 January 2018

1 reference

12 December 2020

Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein

1 reference

12 December 2020

Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation

1 reference

12 December 2020

Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes.

1 reference

12 December 2020

The role of membrane transporters in cellular resistance to anticancer nucleoside drugs.

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12 December 2020

Micro-array analysis of resistance for gemcitabine results in increased expression of ribonucleotide reductase subunits

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12 December 2020

Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy

1 reference

12 December 2020

Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

1 reference

12 December 2020

Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers.

1 reference

12 December 2020

Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3).

1 reference

12 December 2020

Physical and Functional Interactions between USF and Sp1 Proteins Regulate Human Deoxycytidine Kinase Promoter Activity

1 reference

12 December 2020

Na+-dependent nucleoside transport in liver: two different isoforms from the same gene family are expressed in liver cells

1 reference

12 December 2020

Polycomb silencers control cell fate, development and cancer

1 reference

12 December 2020

Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancer

1 reference

12 December 2020

Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia

1 reference

12 December 2020

Chemoradiation with gemcitabine for cervical cancer in patients with renal failure

1 reference

12 December 2020

Functionally relevant histone-DNA interactions extend beyond the classically defined nucleosome core region

1 reference

12 December 2020

Compensatory effects of the human nucleoside transporters on the response to nucleoside-derived drugs in breast cancer MCF7 cells.

1 reference

12 December 2020

Mammalian nucleoside transporters

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12 December 2020

Histone methylation versus histone acetylation: new insights into epigenetic regulation

1 reference

12 December 2020

Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer

1 reference

12 December 2020

Decitabine (5-Aza-2'-deoxycytidine) decreased DNA methylation and expression of MDR-1 gene in K562/ADM cells

1 reference

12 December 2020

Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1

1 reference

12 December 2020

Chemical mechanisms of histone lysine and arginine modifications

1 reference

12 December 2020

Functional and molecular characteristics of Na(+)-dependent nucleoside transporters.

1 reference

12 December 2020

Nucleoside transporter profiles in human pancreatic cancer cells: role of hCNT1 in 2',2'-difluorodeoxycytidine- induced cytotoxicity.

1 reference

12 December 2020

Nutritional regulation of nucleoside transporter expression in rat small intestine

1 reference

12 December 2020

Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: relationship to molecular mechanisms of gemcitabine resistance and survival

1 reference

12 December 2020

Gemcitabine and vinorelbine in pemetrexed-pretreated patients with malignant pleural mesothelioma

1 reference

12 December 2020

Nucleoside transporters: molecular biology and implications for therapeutic development

1 reference

12 December 2020

Action of 2',2'-difluorodeoxycytidine on DNA synthesis

1 reference

12 December 2020

Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo

1 reference

12 December 2020

Ribonucleotide reductase M1 (RRM1) 2464G>A polymorphism shows an association with gemcitabine chemosensitivity in cancer cell lines.

1 reference

12 December 2020

A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer

1 reference

12 December 2020

Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation

1 reference

12 December 2020

Evolutionary history of histone demethylase families: distinct evolutionary patterns suggest functional divergence

1 reference

12 December 2020

Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients

1 reference

12 December 2020

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12 December 2020

The absence of human equilibrative nucleoside transporter 1 expression predicts nonresponse to gemcitabine-containing chemotherapy in non-small cell lung cancer

1 reference

12 December 2020

Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors

1 reference

12 December 2020

Na(+)-dependent purine nucleoside transporter from human kidney: cloning and functional characterization

1 reference

12 December 2020

Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

1 reference

12 December 2020

cN-II expression predicts survival in patients receiving gemcitabine for advanced non-small cell lung cancer.

1 reference

12 December 2020

Excision of 2',2'-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA

1 reference

12 December 2020

Expression of the high-affinity fluoropyrimidine-preferring nucleoside transporter hCNT1 correlates with decreased disease-free survival in breast cancer

1 reference

12 December 2020

Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine

1 reference

12 December 2020

Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines

1 reference

12 December 2020

Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells

1 reference

12 December 2020

Effect of 5-azacytidine and congeners on DNA methylation and expression of deoxycytidine kinase in the human lymphoid cell lines CCRF/CEM/0 and CCRF/CEM/dCk-1.

1 reference

12 December 2020

Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics

1 reference

12 December 2020

Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B.

1 reference

12 December 2020

Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.

1 reference

12 December 2020

Molecular determinants of specificity for synthetic nucleoside analogs in the concentrative nucleoside transporter, CNT2.

1 reference

12 December 2020

Genetic determinants of cancer drug efficacy and toxicity: practical considerations and perspectives

1 reference

12 December 2020

Cellular pharmacology of gemcitabine

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12 December 2020

Structure and function of eukaryotic DNA methyltransferases

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12 December 2020

The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma.

1 reference

12 December 2020

Determinants of resistance to 2',2'-difluorodeoxycytidine (gemcitabine).

1 reference

12 December 2020

Gemcitabine plus oxaliplatin (GEMOX) in pretreated patients with advanced ovarian cancer: a multicenter phase II study of the Hellenic Oncology Research Group (HORG).

1 reference

12 December 2020

Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin

1 reference

12 December 2020

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

1 reference

12 December 2020

Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes

1 reference

12 December 2020

Functional characterization of a nucleoside-derived drug transporter variant (hCNT3C602R) showing altered sodium-binding capacity.

1 reference

12 December 2020

Characterization and functional analysis of the promoter for the human equilibrative nucleoside transporter gene, hENT1

1 reference

12 December 2020

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

12 December 2020

Genomic organization and expression of the mouse equilibrative, nitrobenzylthioinosine-sensitive nucleoside transporter 1 (ENT1) gene.

1 reference

12 December 2020

Genetic and epigenetic alterations of the reduced folate carrier in untreated diffuse large B-cell lymphoma

1 reference

12 December 2020

Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)

1 reference

12 December 2020

Lack of cross-resistance with gemcitabine and cytarabine in cladribine-resistant HL60 cells with elevated 5'-nucleotidase activity

1 reference

12 December 2020

Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study

1 reference

12 December 2020

Nucleoside transporters and liver cell growth

1 reference

12 December 2020

Selective loss of nucleoside carrier expression in rat hepatocarcinomas.

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12 December 2020

[Updates on gemcitabine on metastatic breast cancer]

1 reference

12 December 2020

Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10)

1 reference

12 December 2020

Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer

1 reference

12 December 2020

Modulatory activity of 2',2'-difluorodeoxycytidine on the phosphorylation and cytotoxicity of arabinosyl nucleosides

1 reference

12 December 2020

Cloning and expression of human deoxycytidine kinase cDNA

1 reference

12 December 2020

Pharmacodynamic and DNA methylation studies of high-dose 1-beta-D-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia

1 reference

12 December 2020

Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity.

1 reference

12 December 2020

Regulation of nucleoside transport by lipopolysaccharide, phorbol esters, and tumor necrosis factor-alpha in human B-lymphocytes

1 reference

12 December 2020

Ribonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabine

1 reference

12 December 2020

Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants.

1 reference

12 December 2020

Phase III trial of gemcitabine plus cisplatin versus cisplatin alone in patients with locally advanced or metastatic non-small-cell lung cancer

1 reference

12 December 2020

Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).

1 reference

12 December 2020

Functional single nucleotide polymorphism haplotypes in the human equilibrative nucleoside transporter 1.

1 reference

12 December 2020

Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer

1 reference

12 December 2020

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

1 reference

12 December 2020

Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[Prime]-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug

1 reference

12 December 2020

Nucleoside analogues: mechanisms of drug resistance and reversal strategies.

1 reference

12 December 2020

Differential expression of human nucleoside transporters in normal and tumor tissue

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12 December 2020

The role of nucleoside transporters in cancer chemotherapy with nucleoside drugs

1 reference

12 December 2020

DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation

1 reference

12 December 2020

Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations

1 reference

12 December 2020

Structure and function of nucleosome assembly proteins

1 reference

12 December 2020

Increased expression of the large subunit of ribonucleotide reductase is involved in resistance to gemcitabine in human mammary adenocarcinoma cells.

1 reference

12 December 2020

10.1007/S12032-009-9349-Y

Identifiers

DOI

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21 August 2017

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