(Q37630750)

English

Marine Streptomyces sp. derived antimycin analogues suppress HeLa cells via depletion HPV E6/E7 mediated by ROS-dependent ubiquitin-proteasome system

scientific article published on 08 February 2017

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Marine Streptomyces sp. derived antimycin analogues suppress HeLa cells via depletion HPV E6/E7 mediated by ROS-dependent ubiquitin-proteasome system (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

ubiquitin-proteasome system

0 references

Streptomyces argillaceus

1 reference

1 reference

Streptomyces orinoci

1 reference

[(2R,3S,7R,8R)-3-[(3-acetamido-2-hydroxybenzoyl)amino]-2-methyl-4,9-dioxo-8-pentyl-1,5-dioxonan-7-yl] 2-methylpropanoate

1 reference

[(2R,3S,7R,8R)-3-[(3-acetamido-2-hydroxybenzoyl)amino]-2-methyl-4,9-dioxo-8-pentyl-1,5-dioxonan-7-yl] propanoate

1 reference

1 reference

1 reference

[(2R,3S,7R,8R)-8-butyl-3-[(3-formamido-2-hydroxybenzoyl)amino]-2-methyl-4,9-dioxo-1,5-dioxonan-7-yl] acetate

1 reference

[(2R,3S,7R,8R)-3-[(3-acetamido-2-hydroxybenzoyl)amino]-8-heptyl-2-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylpentanoate

1 reference

[(2R,3S,7R,8R)-3-[(3-amino-2-hydroxybenzoyl)amino]-8-hexyl-2-methyl-4,9-dioxo-1,5-dioxonan-7-yl] (2S)-2-methylbutanoate

1 reference

[(2R,3S,7R,8R)-3-[(3-acetamido-2-hydroxybenzoyl)amino]-8-heptyl-2-methyl-4,9-dioxo-1,5-dioxonan-7-yl] acetate

1 reference

[(2R,3S,7R,8R)-3-[(3-acetamido-2-hydroxybenzoyl)amino]-8-heptyl-2-methyl-4,9-dioxo-1,5-dioxonan-7-yl] (2S)-2-methylpentanoate

1 reference

[(2R,3S,7R,8R)-3-[(3-acetamido-2-hydroxybenzoyl)amino]-2-methyl-8-(3-methylbutyl)-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylpentanoate

1 reference

Deformylated antimycin A1a

1 reference

1 reference

2-Methylpropanoic acid (3S,4R,7R,8R,9S)-3-[(3-amino-2-hydroxybenzoyl)amino]-4,9-dimethyl-2,6-dioxo-7-hexyl-1,5-dioxonan-8-yl ester

1 reference

1 reference

1 reference

1 reference

author name string

Weiyi Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Qian Che

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Hongsheng Tan

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Xin Qi

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Jing Li

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Dehai Li

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Qianqun Gu

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Tianjiao Zhu

8

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Ming Liu

9

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

0 references

publication date

8 February 2017

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

full work available at URL

https://www.nature.com/articles/srep42180.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/srep42180?email=unpaywall_01@example.com

Scientific Reports

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

1

1 reference

http://api.crossref.org/works/10.1038%2Fsrep42180

42180

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 February 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

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online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/srep42180?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

https://scigraph.springernature.com/pub.10.1038/srep42180

0 references

The antimycin A-sensitive pathway of cyclic electron flow: from 1963 to 2015.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Docosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin-proteasome system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Functional regulatory role of STAT3 in HPV16-mediated cervical carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Non-canonical ubiquitin-based signals for proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Ubiquitin-proteasome pathway and cellular responses to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Oncogenic role of EAPII in lung cancer development and its activation of the MAPK-ERK pathway.

1 reference

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23 August 2017

Aberrant expression and constitutive activation of STAT3 in cervical carcinogenesis: implications in high-risk human papillomavirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Human papillomavirus oncoproteins: pathways to transformation

1 reference

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23 August 2017

Cervical cancer prevention: new tools and old barriers

1 reference

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23 August 2017

Modulation of apoptosis by early human papillomavirus proteins in cervical cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Potent inhibitors of pro-inflammatory cytokine production produced by a marine-derived bacterium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

E3 ubiquitin ligase E6AP-mediated TSC2 turnover in the presence and absence of HPV16 E6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Mitochondria, oxidants, and aging

1 reference

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23 August 2017

The tumor suppressor protein p16(INK4a) and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system. Direct evidence for ubiquitination at the N-terminal residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Human papillomavirus 16 E6 oncoprotein interferences with insulin signaling pathway by binding to tuberin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis

1 reference

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23 August 2017

Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

The role of human papillomavirus oncoproteins E6 and E7 in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Degradation of the E7 human papillomavirus oncoprotein by the ubiquitin-proteasome system: targeting via ubiquitination of the N-terminal residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

23 August 2017

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

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23 August 2017

Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

6 September 2017

Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells

1 reference

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6 September 2017

ERK Signaling Pathway Is Involved in HPV-16 E6 but not E7 Oncoprotein-Induced HIF-1α Protein Accumulation in NSCLC Cells

1 reference

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6 September 2017

13-Oxyingenol dodecanoate, a cytotoxic ingenol derivative, induces mitochondrial apoptosis and caspase-dependent Akt decrease in K562 cells

1 reference

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6 September 2017

Isocyclopamine, a novel synthetic derivative of cyclopamine, reverts doxorubicin resistance in MCF-7/ADR cells by increasing intracellular doxorubicin accumulation and downregulating breast cancer stem-like cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

6 September 2017

Signaling pathways in HPV-associated cancers and therapeutic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

6 September 2017

Induction of apoptosis by antimycin A in differentiated PC12 cell line

1 reference

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6 September 2017

E6 variants of human papillomavirus 18 differentially modulate the protein kinase B/phosphatidylinositol 3-kinase (akt/PI3K) signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

14 September 2017

2-Methoxy antimycin reveals a unique mechanism for Bcl-x(L) inhibition

1 reference

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14 September 2017

Preclinical pharmacology of 2-methoxyantimycin A compounds as novel antitumor agents

1 reference

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14 September 2017

Ubiquitination and proteasome degradation of the E6 proteins of human papillomavirus types 11 and 18.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

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Hydrogen peroxide stimulates ubiquitin-conjugating activity and expression of genes for specific E2 and E3 proteins in skeletal muscle myotubes

1 reference

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1 reference

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Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A.

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

25 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

25 June 2018

Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

25 June 2018

Antimycin A as a mitochondria damage agent induces an S phase arrest of the cell cycle in HeLa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

25 June 2018

Oxidoreduction of cytochrome b in the presence of antimycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

25 June 2018

Hybrid Isoprenoids from a Reeds Rhizosphere Soil Derived Actinomycete Streptomyces sp. CHQ-64

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

Human papillomavirus: E6 and E7 oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

An ROS generator, antimycin A, inhibits the growth of HeLa cells via apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

HPV integration begins in the tonsillar crypt and leads to the alteration of p16, EGFR and c-myc during tumor formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

Monitoring of ubiquitin-dependent proteolysis with green fluorescent protein substrates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

A new antibiotic, antimycin Ag, produced by Streptomyces sp. K01-0031.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

N-acetyl-L-cysteine inhibits 26S proteasome function: implications for effects on NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5296914

1 September 2018

Antimycin A components. II. Identification and analysis of antimycin A fractions by pyrolysis-gas liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/28176847

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new fungicide produced by a Streptomyces sp. GAAS7310

1 reference

https://pubmed.ncbi.nlm.nih.gov/28176847

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimycins, inhibitors of ATP-citrate lyase, from a Streptomyces sp

1 reference

https://pubmed.ncbi.nlm.nih.gov/28176847

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimycin A18 produced by an endophytic Streptomyces albidoflavus isolated from a mangrove plant

1 reference

https://pubmed.ncbi.nlm.nih.gov/28176847

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP42180

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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