(Q37633176)

21 August 2017

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title

Pharmacogenetics of breast cancer therapies (English)

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21 August 2017

Daniel L Hertz

1

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21 August 2017

Howard L McLeod

series ordinal

2

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21 August 2017

Janelle M Hoskins

series ordinal

3

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21 August 2017

publication date

1 October 2009

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21 August 2017

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21 August 2017

volume

18 Suppl 3

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21 August 2017

page(s)

S59-63

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Adjuvant chemotherapy with and without tamoxifen in the treatment of primary breast cancer: 5-year results from the National Surgical Adjuvant Breast and Bowel Project Trial

21 August 2017

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Progesterone receptor is a significant factor associated with clinical outcomes and effect of adjuvant tamoxifen therapy in breast cancer patients

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7 January 2021

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7 January 2021

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

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7 January 2021

Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer

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7 January 2021

Development of the 21-gene assay and its application in clinical practice and clinical trials

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7 January 2021

American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

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7 January 2021

A "silent" polymorphism in the MDR1 gene changes substrate specificity

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7 January 2021

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

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7 January 2021

The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex

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7 January 2021

Cytotoxicity mediated by human Fc receptors for IgG.

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7 January 2021

A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease

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7 January 2021

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

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7 January 2021

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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7 January 2021

Pilot Study of the Mechanism of Action of Preoperative Trastuzumab in Patients with Primary Operable Breast Tumors Overexpressing HER2

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7 January 2021

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?

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7 January 2021

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7 January 2021

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

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7 January 2021

Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma

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7 January 2021

FCGR3A gene polymorphisms may correlate with response to frontline R-CHOP therapy for diffuse large B-cell lymphoma.

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7 January 2021

Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.

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7 January 2021

FcγRIIIa and FcγRIIa polymorphisms do not predict response to rituximab in B-cell chronic lymphocytic leukemia

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7 January 2021

The efficacy of rituximab plus Hyper-CVAD regimen in mantle cell lymphoma is independent of FCgammaRIIIa and FCgammaRIIa polymorphisms

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7 January 2021

FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

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7 January 2021

Dose-response relationship and pharmacogenetics of anti-RhD monoclonal antibodies

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7 January 2021

Evidence for linkage disequilibrium between Fcgamma RIIIa-V158F and Fcgamma RIIa-H131R polymorphisms in white patients, and for an Fcgamma RIIIa-restricted influence on the response to therapeutic antibodies

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7 January 2021

Selective estrogen receptor modulators (SERMs): mechanisms of anticarcinogenesis and drug resistance

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7 January 2021

Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

1 reference

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7 January 2021

Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine

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7 January 2021

Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen

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7 January 2021

Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.

1 reference

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7 January 2021

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells

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7 January 2021

Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment

1 reference

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7 January 2021

Chromosomal assignment of human cytochrome P-450 (debrisoquine/sparteine type) to chromosome 22.

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7 January 2021

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

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7 January 2021

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment

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7 January 2021

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

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7 January 2021

Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes

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7 January 2021

The CYP2D6*4 polymorphism affects breast cancer survival in tamoxifen users

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7 January 2021

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen

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7 January 2021

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

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7 January 2021

Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer

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7 January 2021

Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients

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7 January 2021

Guidelines for the adjuvant treatment of postmenopausal women with endocrine-responsive breast cancer: past, present and future recommendations

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7 January 2021

10.1016/S0960-9776(09)70275-9

Identifiers

DOI

1 reference

21 August 2017

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