(Q37633380)

English

Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261962%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261962%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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toll-like receptor

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3

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1 March 2020

Roberto Ruiz-Cordero

4

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1 March 2020

5

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1 March 2020

author name string

Arumugam R Jayakumar

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1 March 2020

Xiao Y Tong

2

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1 March 2020

Michael D Norenberg

6

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1 March 2020

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22 November 2013

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1 March 2020

number of pages

14

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inferred from page(s)

Journal of Neurochemistry

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1 March 2020

128

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1 March 2020

6

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1 March 2020

890-903

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261962%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Brain edema in acute liver failure: role of neurosteroids

1 reference

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1 reference

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23 August 2017

Primary cultures of astrocytes: their value in understanding astrocytes in health and disease.

1 reference

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23 August 2017

Role of cerebral endothelial cells in the astrocyte swelling and brain edema associated with acute hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases.

1 reference

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23 August 2017

Clinical practice. Chronic hepatitis C infection

1 reference

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23 August 2017

Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells

1 reference

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23 August 2017

NF-κB in the mechanism of brain edema in acute liver failure: studies in transgenic mice

1 reference

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23 August 2017

EF1alpha and RPL13a represent normalization genes suitable for RT-qPCR analysis of bone marrow derived mesenchymal stem cells

1 reference

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23 August 2017

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

1 reference

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23 August 2017

Brain edema in acute liver failure: inhibition by L-histidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Diffusion tensor imaging supports the cytotoxic origin of brain edema in a rat model of acute liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Neurophysiological investigations of hepatic encephalopathy: ISHEN practice guidelines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Experimental models of hepatic encephalopathy: ISHEN guidelines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Protein kinase G is involved in ammonia-induced swelling of astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Signaling factors in the mechanism of ammonia neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Na-K-Cl Cotransporter-1 in the mechanism of ammonia-induced astrocyte swelling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Endotoxemia produces coma and brain swelling in bile duct ligated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Hepatic encephalopathy: a review of its pathophysiology and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Lipopolysaccharide signaling in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Cytotoxic edema is responsible for raised intracranial pressure in fulminant hepatic failure: in vivo demonstration using diffusion-weighted MRI in human subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Signalling specificity in GPCR-dependent Ca2+ signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Monitoring of brain water by chemical shift imaging during ammonia-induced brain swelling in rats after portacaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

23 August 2017

The neurological manifestations of acute liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

6 September 2017

Hepatic encephalopathy: suspect it early in patients with cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

6 September 2017

Volume measurements in cultured primary astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

6 September 2017

Correlation of plasma and brain amino acid and putative neurotransmitter alterations during acute hepatic coma in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

6 September 2017

Ammonia-induced brain swelling and neurotoxicity in an organotypic slice model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

14 September 2017

Src kinase participates in LPS-induced activation of NADPH oxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

14 September 2017

Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

14 September 2017

Plasticity of astrocytes in primary cultures: an experimental tool and a reason for methodological caution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

14 September 2017

Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation

1 reference

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28 September 2017

Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands

1 reference

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28 September 2017

Bacterial and fungal infection in acute liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

28 September 2017

Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: characterization of an improved model and study of amino acid-ergic neurotransmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

28 September 2017

Role of toll-like receptor 4 in mediating multiorgan dysfunction in mice with acetaminophen induced acute liver failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Prevention and treatment of hepatic encephalopathy: focusing on gut microbiota.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Marked potentiation of cell swelling by cytokines in ammonia-sensitized cultured astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Calcium in the mechanism of ammonia-induced astrocyte swelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

K(+)-, hypoosmolarity-, and NH4(+)-induced taurine release from cultured rabbit Müller cells: role of Na+ and Cl- ions and relation to cell volume changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Brain microvessel endothelial cells in tissue culture: a model for study of blood-brain barrier permeability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Electron microscopy in human hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: ultrastructure and integrity of the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Anisotonic media and glutamate-induced ion transport and volume responses in primary astrocyte cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

The benzodiazepine receptor in cultured astrocytes from genetically epilepsy-prone rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Ammonia-induced astrocyte swelling in primary culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

Ammonia and related amino acids in the pathogenesis of brain edema in acute ischemic liver failure in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

25 June 2018

A light and electron microscopic study of experimental portal-systemic (ammonia) encephalopathy. Progression and reversal of the disorder

1 reference

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25 June 2018

Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS.

1 reference

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1 September 2018

Pharmacological modulators of nitric oxide signaling and contextual fear conditioning in mice

1 reference

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1 September 2018

Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Lactate contributes to ammonia-mediated astroglial dysfunction during hyperammonemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Measurement of cytotoxic and interstitial components of cerebral edema in acute hepatic failure by diffusion tensor imaging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Oxidative stress and mitogen-activated protein kinase phosphorylation mediate ammonia-induced cell swelling and glutamate uptake inhibition in cultured astrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Moderate-to-severe ischemic conditions increase activity and phosphorylation of the cerebral microvascular endothelial cell Na+-K+-Cl- cotransporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Fulminant hepatic failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

How does peripheral lipopolysaccharide induce gene expression in the brain of rats?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Azoxymethane-induced fulminant hepatic failure in C57BL/6J mice: characterization of a new animal model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Prospective study comparing the efficacy of prophylactic parenteral antimicrobials, with or without enteral decontamination, in patients with acute liver failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Regional cerebral edema and chloride space in galactosamine-induced liver failure in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Swelling, acidosis, and irreversible damage of glial cells from exposure to arachidonic acid in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951576

1 September 2018

Ammonia-induced swelling of rat cerebral cortical slices: implications for the pathogenesis of brain edema in acute hepatic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxemia in patients with chronic liver diseases: relationship to severity of liver diseases, presence of esophageal varices, and hyperdynamic circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioacetamide-induced hepatic encephalopathy in the rat. I. Preliminary morphological and biochemical observations

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Na-K-Cl cotransporter in the brain edema of acute liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method using 3-O-methyl-D-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Balancing pro- and anti-inflammatory TLR4 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF alpha, IL-1 beta and IL-6 production by peripheral blood monocytes in patients with renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic acid-induced swelling in incubated rat brain cortical slices. Effect of bovine serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of cytokines by brain endothelial cells: A polarized response to lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of taurine transport and brain edema in rats with simple hyperammonemia or liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24261962

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/JNC.12516

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261962%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261962%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24261962%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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