(Q37639223)

21 August 2017

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title

The mitochondrial kinase PINK1, stress response and Parkinson's disease (English)

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21 August 2017

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Marina Jendrach

1

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21 August 2017

Suzana Gispert

2

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21 August 2017

Filomena Ricciardi

3

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21 August 2017

Michael Klinkenberg

4

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21 August 2017

Rudolf Schemm

5

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21 August 2017

Georg Auburger

6

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21 August 2017

language of work or name

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1 December 2009

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Journal of Bioenergetics and Biomembranes

21 August 2017

published in

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21 August 2017

volume

41

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21 August 2017

issue

6

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21 August 2017

page(s)

481-486

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https://scigraph.springernature.com/pub.10.1007/s10863-009-9256-0

21 August 2017

exact match

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cites work

PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease

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12 December 2020

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

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12 December 2020

The PINK1/Parkin pathway regulates mitochondrial morphology

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12 December 2020

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

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12 December 2020

Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

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12 December 2020

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

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12 December 2020

Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila

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12 December 2020

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

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12 December 2020

Enhanced sensitivity to group II mGlu receptor activation at corticostriatal synapses in mice lacking the familial parkinsonism-linked genes PINK1 or Parkin.

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12 December 2020

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

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12 December 2020

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

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12 December 2020

Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking

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12 December 2020

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

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12 December 2020

Induction of Parkinson disease-related proteins in motor neurons after transient spinal cord ischemia in rabbits.

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12 December 2020

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

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12 December 2020

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

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12 December 2020

Mitochondrial autophagy as a compensatory response to PINK1 deficiency

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12 December 2020

Structural implications of mitochondrial dynamics

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12 December 2020

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

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12 December 2020

Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth

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12 December 2020

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

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12 December 2020

Inhibition of mitochondrial bioenergetics: the effects on structure of mitochondria in the cell and on apoptosis

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12 December 2020

Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress

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12 December 2020

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.

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12 December 2020

Molecular interaction between parkin and PINK1 in mammalian neuronal cells

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12 December 2020

BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential

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12 December 2020

Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation.

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12 December 2020

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

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12 December 2020

Parkinson patient fibroblasts show increased alpha-synuclein expression

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12 December 2020

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

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12 December 2020

Mitochondrial fusion and fission in the control of apoptosis

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12 December 2020

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux

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12 December 2020

Hydrogen peroxide produced inside mitochondria takes part in cell-to-cell transmission of apoptotic signal

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12 December 2020

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

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12 December 2020

Stanley Fahn Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered

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12 December 2020

Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis.

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12 December 2020

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

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12 December 2020

Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice

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12 December 2020

The beta subunit determines the ligand binding properties of synaptic glycine receptors

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12 December 2020

Loss of PINK1 function affects development and results in neurodegeneration in zebrafish

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12 December 2020

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

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12 December 2020

Molecular pathogenesis of Parkinson disease: insights from genetic studies

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12 December 2020

The kinase domain of mitochondrial PINK1 faces the cytoplasm

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12 December 2020

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

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12 December 2020

Parkin stabilizes PINK1 through direct interaction

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12 December 2020

Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells

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12 December 2020

Dopaminergic function in a family with the PARK6 form of autosomal recessive Parkinson's syndrome

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12 December 2020

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

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12 December 2020

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

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12 December 2020

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

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12 December 2020

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

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12 December 2020

Expression of PINK1 mRNA in human and rodent brain and in Parkinson's disease

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12 December 2020

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

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12 December 2020

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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12 December 2020

PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c.

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12 December 2020

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

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12 December 2020

The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function

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12 December 2020

Expanding the clinical phenotype of SNCA duplication carriers

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12 December 2020

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

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12 December 2020

Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.

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12 December 2020

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

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12 December 2020

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

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12 December 2020

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

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12 December 2020

Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations

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12 December 2020

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

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12 December 2020

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

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12 December 2020

10.1007/S10863-009-9256-0

Identifiers

DOI

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21 August 2017

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