(Q37643750)

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Amino acid substitutions in polymerase basic protein 2 gene contribute to the pathogenicity of the novel A/H7N9 influenza virus in mammalian hosts.

scientific article published on 08 January 2014

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4 March 2020

Amino acid substitutions in polymerase basic protein 2 gene contribute to the pathogenicity of the novel A/H7N9 influenza virus in mammalian hosts (English)

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4 March 2020

Chris Ka Pun Mok

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4 March 2020

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4 March 2020

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Maxime Lestra

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Sin Fun Sia

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4 March 2020

Yi Guan

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8 January 2014

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4 March 2020

Journal of Virology

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4 March 2020

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4 March 2020

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4 March 2020

3568-3576

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4 March 2020

Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

The genesis and source of the H7N9 influenza viruses causing human infections in China

1 reference

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23 August 2017

Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A(H7N9) virus

1 reference

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23 August 2017

Pathogenicity of the novel A/H7N9 influenza virus in mice.

1 reference

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23 August 2017

Detection of mild to moderate influenza A/H7N9 infection by China's national sentinel surveillance system for influenza-like illness: case series.

1 reference

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23 August 2017

Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses

1 reference

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23 August 2017

Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome

1 reference

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23 August 2017

Epidemiology of human infections with avian influenza A(H7N9) virus in China.

1 reference

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23 August 2017

Genetic analysis of novel avian A(H7N9) influenza viruses isolated from patients in China, February to April 2013.

1 reference

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23 August 2017

Human infection with a novel avian-origin influenza A (H7N9) virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Key molecular factors in hemagglutinin and PB2 contribute to efficient transmission of the 2009 H1N1 pandemic influenza virus

1 reference

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23 August 2017

Human-like PB2 627K influenza virus polymerase activity is regulated by importin-α1 and -α7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Detection of highly pathogenic influenza and pandemic influenza virus in formalin fixed tissues by immunohistochemical methods

1 reference

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23 August 2017

Reversion of PB2-627E to -627K during replication of an H5N1 Clade 2.2 virus in mammalian hosts depends on the origin of the nucleoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Amino acid residues 253 and 591 of the PB2 protein of avian influenza virus A H9N2 contribute to mammalian pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Selection of H5N1 influenza virus PB2 during replication in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

An inhibitory activity in human cells restricts the function of an avian-like influenza virus polymerase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3957932

23 August 2017

Growth of H5N1 influenza A viruses in the upper respiratory tracts of mice.

1 reference

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23 August 2017

Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model

1 reference

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23 August 2017

Lethality to ferrets of H5N1 influenza viruses isolated from humans and poultry in 2004.

1 reference

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23 August 2017

Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses

1 reference

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23 August 2017

Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells

1 reference

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6 September 2017

Biological features of novel avian influenza A (H7N9) virus

1 reference

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6 September 2017

Evidence for avian and human host cell factors that affect the activity of influenza virus polymerase

1 reference

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14 September 2017

PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice

1 reference

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14 September 2017

Avian-origin influenza A(H7N9) infection in influenza A(H7N9)-affected areas of China: a serological study

1 reference

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25 June 2018

Determinants of antiviral effectiveness in influenza virus A subtype H5N1.

1 reference

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1 September 2018

The molecular basis of the pathogenicity of the Dutch highly pathogenic human influenza A H7N7 viruses

1 reference

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1 September 2018

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10.1128/JVI.02740-13

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4 March 2020

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4 March 2020

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4 March 2020

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