(Q37644276)

21 February 2018

review article

1 reference

title

Co-receptors and recognition of self at the immunological synapse (English)

1 reference

21 February 2018

1 reference

Nicholas R J Gascoigne

series ordinal

1

object named as

Nicholas R J Gascoigne

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21 February 2018

Tomasz Zal

2

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21 February 2018

Pia P Yachi

series ordinal

3

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21 February 2018

John A H Hoerter

series ordinal

4

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21 February 2018

publication date

1 January 2010

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21 February 2018

Current Topics in Microbiology and Immunology

published in

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21 February 2018

volume

340

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21 February 2018

page(s)

171-189

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21 February 2018

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

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TCR complex-activated CD8 adhesion function by human T cells

25 June 2018

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The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality

25 June 2018

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Increased mobility of major histocompatibility complex I-peptide complexes decreases the sensitivity of antigen recognition

25 June 2018

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Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

25 June 2018

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Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity

25 June 2018

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T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state

25 June 2018

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A constant affinity threshold for T cell tolerance

25 June 2018

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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

25 June 2018

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Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response

25 June 2018

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Altered peptide ligands induce delayed CD8-T cell receptor interaction--a role for CD8 in distinguishing antigen quality

25 June 2018

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

25 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

CD8 kinetically promotes ligand binding to the T-cell antigen receptor.

25 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

25 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Using live FRET imaging to reveal early protein-protein interactions during T cell activation

25 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Photobleaching-corrected FRET efficiency imaging of live cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

CD4 raft association and signaling regulate molecular clustering at the immunological synapse site

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Molecular interactions at the T cell-antigen-presenting cell interface

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

T cell adhesion lowers the threshold for antigen detection

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Molecular interactions mediating T cell antigen recognition

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

CD4 dimers constitute the functional component required for T cell activation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Rare, structurally homologous self-peptides promote thymocyte positive selection

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Cutting edge: single-chain trimers of MHC class I molecules form stable structures that potently stimulate antigen-specific T cells and B cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

T cell receptor signaling precedes immunological synapse formation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Differential clustering of CD4 and CD3zeta during T cell recognition

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Dimeric association and segmental variability in the structure of human CD4

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Control of MHC restriction by TCR Valpha CDR1 and CDR2

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

T-cell-receptor affinity and thymocyte positive selection

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Cell-cell adhesion mediated by CD8 and MHC class I molecules

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Interaction between CD4 and class II MHC molecules mediates cell adhesion

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Substitution at residue 227 of H-2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, cytotoxic T lymphocytes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Empty MHC class I molecules come out in the cold

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Activated CD8 binding to class I protein mediated by the T-cell receptor results in signalling

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Identification of palmitoylation sites on CD4, the human immunodeficiency virus receptor.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Do T cells need endogenous peptides for activation?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

T cell killing does not require the formation of a stable mature immunological synapse.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Direct observation of ligand recognition by T cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Preferential expression of TCR V alpha regions in CD4/CD8 subsets: class discrimination or co-receptor recognition?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5788015

Molecular analysis of H-2-deficient lymphoma lines. Distinct defects in biosynthesis and association of MHC class I heavy chains and beta 2-microglobulin observed in cells with increased sensitivity to NK cell lysis

3 December 2018

1 reference

12 December 2020

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1 reference

12 December 2020

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

1 reference

12 December 2020

Activators of protein kinase C induce dissociation of CD4, but not CD8, from p56lck

1 reference

12 December 2020

CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes

1 reference

12 December 2020

Role of CD8beta domains in CD8 coreceptor function: importance for MHC I binding, signaling, and positive selection of CD8+ T cells in the thymus

1 reference

12 December 2020

T-cell receptor binding kinetics in T-cell development and activation

1 reference

12 December 2020

The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model

1 reference

12 December 2020

Self peptide/MHC class I complexes have a negligible effect on the response of some CD8+ T cells to foreign antigen

1 reference

12 December 2020

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

1 reference

12 December 2020

Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

1 reference

12 December 2020

10.1007/978-3-642-03858-7_9

Identifiers

DOI

1 reference

21 February 2018

PMC publication ID

5788015

1 reference

21 February 2018

PubMed publication ID

19960314

1 reference

21 February 2018