(Q37654714)

21 August 2017

1 reference

title

Signal transduction of the (pro)renin receptor as a novel therapeutic target for preventing end-organ damage (English)

1 reference

21 August 2017

4

Thomas Unger

1 reference

21 August 2017

1

Heiko Funke-Kaiser

1 reference

21 August 2017

Frank S Zollmann

2

1 reference

PubMed ID

20010781

21 August 2017

Jan H Schefe

series ordinal

3

1 reference

PubMed ID

20010781

21 August 2017

language of work or name

1 reference

11 December 2009

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21 August 2017

Hypertension Research

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21 August 2017

33

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21 August 2017

2

1 reference

21 August 2017

98-104

1 reference

https://scigraph.springernature.com/pub.10.1038/hr.2009.206

21 August 2017

0 references

cites work

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Akt/PKB signaling in cancer: a function in cell motility and invasion

21 January 2018

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Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin

21 January 2018

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Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing

21 January 2018

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https://api.crossref.org/works/10.1038%2FHR.2009.206

Intracellular renin and the nature of intracrine enzymes

21 January 2018

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Renin/prorenin-receptor biochemistry and functional significance

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development.

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

A novel angiotensin II type 2 receptor signaling pathway: possible role in cardiac hypertrophy

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Angiotensin II stimulates protein synthesis and inhibits proliferation in primary cultures of rat adrenal glomerulosa cells

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Survival kinases in ischemic preconditioning and postconditioning.

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7 January 2021

A new hepatocytic isoform of PLZF lacking the BTB domain interacts with ATP7B, the Wilson disease protein, and positively regulates ERK signal transduction

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Identification of 315 genes essential for early zebrafish development

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Incidence and epidemiology of heart failure

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Antihypertensive treatment: should it be titrated to blood pressure reduction or to target organ damage regression?

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The epidemiology of chronic kidney disease

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

End-stage renal disease in the USA: data from the United States Renal Data System

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Diabetic microvascular complications: can patients at risk be identified? A review.

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

https://api.crossref.org/works/10.1038%2FHR.2009.206

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7 January 2021

Prevalence and causes of visual impairment according to World Health Organization and United States criteria in an aged, urban Scandinavian population: the Copenhagen City Eye Study

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https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Blood pressure-independent impact of antihypertensive agents on cardiovascular and renal disease

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Angiotensin II and trials of cardiovascular outcomes

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Elevated blood pressure and heart rate in human renin receptor transgenic rats.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

(Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Drug discovery for overcoming chronic kidney disease (CKD): new therapy for CKD by a (pro)renin-receptor-blocking decoy peptide

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The Renin Academy Summit: advancing the understanding of renin science

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Characterization of a functional (pro)renin receptor in rat brain neurons

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Role of nonproteolytically activated prorenin in pathologic, but not physiologic, retinal neovascularization

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

(Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Tissue activity of circulating prorenin

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Plasma prorenin activity and complications in children with insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Effects of chronic infusion of renin inhibitor A-64662 in sodium-depleted monkeys

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prolonged duration of blood pressure response to enalkiren, the novel dipeptide renin inhibitor, in essential hypertension

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Interpretation of plasma renin concentration in patients receiving aliskiren therapy

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The difficult conception, birth and delivery of a renin inhibitor: controversies around aliskiren

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Aliskiren, the first renin inhibitor for treating hypertension: reactive renin secretion may limit its effectiveness

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Aliskiren fails to lower blood pressure in patients who have either low PRA levels or whose PRA falls insufficiently or reactively rises

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Aliskiren monotherapy results in the greatest and the least blood pressure lowering in patients with high- and low-baseline PRA levels, respectively

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Newly developed renin and prorenin assays and the clinical evaluation of renin inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Renin/prorenin receptors

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Critical review of prorenin and (pro)renin receptor research

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Association of (Pro)renin Receptor Gene Polymorphism With Blood Pressure in Japanese Men: The Ohasama Study

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Vacuolar and plasma membrane proton-adenosinetriphosphatases

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

https://api.crossref.org/works/10.1038%2FHR.2009.206

1 reference

7 January 2021

Genomic characterization and expression analysis of the first nonmammalian renin genes from zebrafish and pufferfish.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prorenin Induces Intracellular Signaling in Cardiomyocytes Independently of Angiotensin II

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

An alternative transcript of the rat renin gene can result in a truncated prorenin that is transported into adrenal mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Intracellular sorting of renin: cell type specific differences and their consequences

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Cytosolic renin is targeted to mitochondria and induces apoptosis in H9c2 rat cardiomyoblasts

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Tissue-specific expression of a rat renin transcript lacking the coding sequence for the prefragment and its stimulation by myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin.

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Hit and lead generation: beyond high-throughput screening

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Regulation of epithelial sodium transport by promyelocytic leukemia zinc finger protein

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.206

7 January 2021

Identifiers

DOI

10.1038/HR.2009.206

1 reference

21 August 2017

1 reference

PubMed ID

20010781