(Q37665378)

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Resveratrol Suppresses Expression of VEGF by Human Retinal Pigment Epithelial Cells: Potential Nutraceutical for Age-related Macular Degeneration

scientific article published on April 2014

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Europe PubMed Central

PMC publication ID

21 August 2017

Resveratrol Suppresses Expression of VEGF by Human Retinal Pigment Epithelial Cells: Potential Nutraceutical for Age-related Macular Degeneration (English)

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Europe PubMed Central

PMC publication ID

21 August 2017

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Chandrasekharam N Nagineni

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Raghavan Raju

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Krishnasai K Nagineni

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Vijay K Kommineni

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Aswini Cherukuri

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

R Krishnan Kutty

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

John J Hooks

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Barbara Detrick

8

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Europe PubMed Central

PMC publication ID

21 August 2017

publication date

1 April 2014

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Europe PubMed Central

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21 August 2017

Aging and Disease

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Europe PubMed Central

PMC publication ID

21 August 2017

5

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Europe PubMed Central

PMC publication ID

21 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

88-100

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Diminishing risk for age-related macular degeneration with nutrition: a current view

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

The role of the immune response in age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Observation of human retinal remodeling in octogenarians with a resveratrol based nutritional supplement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Immunology of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Mechanisms of age-related macular degeneration

1 reference

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Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex

1 reference

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23 August 2017

Nutritional modulation of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

1 reference

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Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1

1 reference

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CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium

1 reference

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23 August 2017

Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway

1 reference

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23 August 2017

Regulation of SIRT1 in cellular functions: role of polyphenols

1 reference

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23 August 2017

Summary results and recommendations from the age-related eye disease study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

IL-11 expression in retinal and corneal cells is regulated by interferon-gamma

1 reference

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23 August 2017

Recent progress in the biology and physiology of sirtuins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Resveratrol: its biologic targets and functional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Vascular endothelial growth factor in eye disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Resveratrol: a multitargeted agent for age-associated chronic diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Age-related macular degeneration and the immune response: implications for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Anti-angiogenic therapy of exudative age-related macular degeneration: current progress and emerging concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Therapeutic potential of resveratrol: the in vivo evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

The role of inflammation in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

The retinal pigment epithelium in visual function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Current concepts in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Prevalence of age-related macular degeneration in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

The biology of VEGF and its receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

A role for local inflammation in the formation of drusen in the aging eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Immunological and aetiological aspects of macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Genomic organization of human and mouse genes for vascular endothelial growth factor C.

1 reference

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23 August 2017

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

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23 August 2017

Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Synergistic effects of gamma interferon on inflammatory mediators that induce interleukin-6 gene expression and secretion by human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Growth factor localization in choroidal neovascular membranes of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Pathophysiology of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

23 August 2017

Ocular neovascularization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

6 September 2017

Anti-VEGF Treatment Strategies for Wet AMD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

6 September 2017

Human retinal pigment epithelium cells as functional models for the RPE in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

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Transport, stability, and biological activity of resveratrol

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A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1.

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6 September 2017

Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

14 September 2017

Prevalence of age-related macular degeneration in the US population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966676

14 September 2017

Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells.

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14 September 2017

Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition.

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14 September 2017

The retinal pigment epithelium: a versatile partner in vision.

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Antioxidant effect of trans-resveratrol in cultured human retinal pigment epithelial cells.

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Increased expression of angiogenic growth factors in age-related maculopathy

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25 June 2018

Regulation of VEGF expression in human retinal cells by cytokines: implications for the role of inflammation in age-related macular degeneration.

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Safety studies conducted on high-purity trans-resveratrol in experimental animals.

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IFN-beta provides immuno-protection in the retina by inhibiting ICAM-1 and CXCL9 in retinal pigment epithelial cells

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Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.

1 reference

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Pathophysiological consequences of VEGF-induced vascular permeability

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Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta

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1 September 2018

Transforming growth factor‐β induces expression of vascular endothelial growth factor in human retinal pigment epithelial cells: Involvement of mitogen‐activated protein kinases

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Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes

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Clinicopathologic correlation of drusen and retinal pigment epithelial abnormalities in age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24729934

12 December 2020

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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