(Q37668713)

English

Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation

scientific article published on March 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

0 references

0 references

cannabinoid receptor

0 references

author name string

Peng Yang

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Liping Wang

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Rentian Feng

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Abdulrahman A Almehizia

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Qin Tong

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Kyaw-Zeyar Myint

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Qin Ouyang

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Mohammed Hamed Alqarni

8

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Lirong Wang

9

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Xiang-Qun Xie

10

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

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publication date

1 March 2013

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

56

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

2045-2058

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Latest advances in novel cannabinoid CB(2) ligands for drug abuse and their therapeutic potential

1 reference

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23 August 2017

Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice

1 reference

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23 August 2017

Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

The endocannabinoid system and cancer: therapeutic implication

1 reference

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23 August 2017

Cannabinoids and bone: friend or foe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Cannabinoids and the skeleton: from marijuana to reversal of bone loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies?

1 reference

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23 August 2017

Role of cannabinoids and endocannabinoids in cerebral ischemia

1 reference

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23 August 2017

Beta-caryophyllene is a dietary cannabinoid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Attenuation of allergic contact dermatitis through the endocannabinoid system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

The endocannabinoid system as an emerging target of pharmacotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Targeting the cannabinoid CB2 receptor: mutations, modeling and development of CB2 selective ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

3D structural model of the G‐protein‐coupled cannabinoid CB2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Spinal and peripheral mechanisms of cannabinoid antinociception: behavioral, neurophysiological and neuroanatomical perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Cannabinergic ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

In vitro and in vivo pharmacological characterization of JTE-907, a novel selective ligand for cannabinoid CB2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Cannabimimetic indoles, pyrroles and indenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656, and AM630

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Molecular characterization of a peripheral receptor for cannabinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

23 August 2017

Synthesis and biological evaluation of heterocyclic ring-fused betulinic acid derivatives as novel inhibitors of osteoclast differentiation and bone resorption.

1 reference

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6 September 2017

Recent advances in fragment-based QSAR and multi-dimensional QSAR methods

1 reference

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6 September 2017

KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

14 September 2017

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

25 June 2018

SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

1 September 2018

3D-QSAR studies of arylpyrazole antagonists of cannabinoid receptor subtypes CB1 and CB2. A combined NMR and CoMFA approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

1 September 2018

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

1 September 2018

(-)-Delta9-tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967766

1 September 2018

The conformational properties of the highly selective cannabinoid receptor ligand CP-55,940

1 reference

https://pubmed.ncbi.nlm.nih.gov/23406429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23406429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of etanercept on osteoclast precursor frequency and enhancing bone marrow oedema in patients with psoriatic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23406429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM3017464

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

ResearchGate publication ID

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