(Q37671489)

21 August 2017

Recombinant antigens based on toxins A and B of Clostridium difficile that evoke a potent toxin-neutralising immune response (English)

1 reference

21 August 2017

Clostridium difficile

0 references

author name string

Michael Maynard-Smith

1

1 reference

21 August 2017

Helen Ahern

2

1 reference

21 August 2017

Joanna McGlashan

3

1 reference

21 August 2017

Philip Nugent

4

1 reference

21 August 2017

Roger Ling

5

1 reference

21 August 2017

Harriet Denton

6

1 reference

21 August 2017

Ruth Coxon

7

1 reference

21 August 2017

John Landon

8

1 reference

21 August 2017

April Roberts

9

1 reference

21 August 2017

Clifford Shone

10

1 reference

21 August 2017

language of work or name

English

0 references

publication date

14 December 2013

1 reference

21 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

Vaccine

1 reference

21 August 2017

32

1 reference

21 August 2017

6

1 reference

21 August 2017

700-705

1 reference

Burden of Clostridium difficile on the healthcare system

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

A chimeric toxin vaccine protects against primary and recurrent Clostridium difficile infection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Treatment with monoclonal antibodies against Clostridium difficile toxins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Clostridium difficile: from obscurity to superbug

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Heterogeneity of large clostridial toxins: importance of Clostridium difficile toxinotypes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Narrative review: the new epidemic of Clostridium difficile-associated enteric disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Bovine antibody-enriched whey to aid in the prevention of a relapse of Clostridium difficile-associated diarrhoea: preclinical and preliminary clinical data.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Active and passive immunization against Clostridium difficile diarrhea and colitis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Comparison of toxinotyping and PCR ribotyping of Clostridium difficile strains and description of novel toxinotypes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Local and systemic neutralizing antibody responses induced by intranasal immunization with the nontoxic binding domain of toxin A from Clostridium difficile

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Immunogenicity of a Salmonella typhimurium aroA aroD vaccine expressing a nontoxic domain of Clostridium difficile toxin A.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Serum antitoxin antibodies mediate systemic and mucosal protection from Clostridium difficile disease in hamsters.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Definition of the single integration site of the pathogenicity locus in Clostridium difficile.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Passive immunization of hamsters against disease caused by Clostridium difficile by use of bovine immunoglobulin G concentrate

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Treatment of refractory and recurrent Clostridium difficile infection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Management of Clostridium difficile infection: thinking inside and outside the box.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Technique for measuring 50% end points in cytotoxicity assays for Clostridium difficile toxins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Development and evaluation of an ovine antibody-based platform for treatment of Clostridium difficile infection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Clostridium difficile diarrhea: pathogenesis, epidemiology, and treatment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Closing in on the toxic domain through analysis of a variant Clostridium difficile cytotoxin B.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Cwp84, a surface-associated cysteine protease, plays a role in the maturation of the surface layer of Clostridium difficile.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

A novel fusion protein containing the receptor binding domains of C. difficile toxin A and toxin B elicits protective immunity against lethal toxin and spore challenge in preclinical efficacy models

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Bivalent recombinant vaccine for botulinum neurotoxin types A and B based on a polypeptide comprising their effector and translocation domains that is protective against the predominant A and B subtypes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on cysteine protease activity.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Identification of formaldehyde-induced modifications in proteins: reactions with model peptides

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Infection of hamsters with epidemiologically important strains of Clostridium difficile

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Modification of surface histidine residues abolishes the cytotoxic activity of Clostridium difficile toxin A.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Pathogenesis of Clostridium difficile infection

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3969267

Clostridium difficile infection in Europe: a hospital-based survey

1 September 2018

2 references

Crossref

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2013.11.099

7 January 2021

https://pubmed.ncbi.nlm.nih.gov/24342251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase I dose finding studies of an adjuvanted Clostridium difficile toxoid vaccine

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2013.11.099

Clostridium difficile-associated infection: a disease of varying severity

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2013.11.099

10.1016/J.VACCINE.2013.11.099

7 January 2021

Identifiers

DOI

1 reference

release_lopynzjndfh23bd6ecfuulfmq4

21 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lopynzjndfh23bd6ecfuulfmq4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

21 August 2017

PubMed publication ID

24342251

1 reference