(Q37677605)

21 August 2017

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title

Delivering the goods: viral and non-viral gene therapy systems and the inherent limits on cargo DNA and internal sequences (English)

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21 August 2017

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Helen Atkinson

1

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21 August 2017

Ronald Chalmers

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

19 January 2010

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21 August 2017

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21 August 2017

volume

138

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21 August 2017

issue

5

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21 August 2017

page(s)

485-498

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Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

21 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10709-009-9434-3

Analyses of cis -acting elements that affect the transposition of Mos1 mariner transposons in vivo

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS10709-009-9434-3

The global regulator H-NS acts directly on the transpososome to promote Tn10 transposition

21 January 2018

1 reference

12 December 2020

Gene therapy: the first two decades and the current state-of-the-art

1 reference

12 December 2020

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

1 reference

12 December 2020

A structural view of cre-loxp site-specific recombination

1 reference

12 December 2020

Chimeric Mos1 and piggyBac transposases result in site-directed integration

1 reference

12 December 2020

Modern thoughts on an ancyent marinere: function, evolution, regulation

1 reference

12 December 2020

Functional dissection of the cis-acting sequences of the Arabidopsis transposable element Tag1 reveals dissimilar subterminal sequence and minimal spacing requirements for transposition.

1 reference

12 December 2020

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

1 reference

12 December 2020

Integrating DNA vectors for gene therapy

1 reference

12 December 2020

Transposition of Mboumar-9: identification of a new naturally active mariner-family transposon

1 reference

12 December 2020

Viral gene therapy strategies: from basic science to clinical application

1 reference

12 December 2020

Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy.

1 reference

12 December 2020

Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer

1 reference

12 December 2020

A chimeric Cre recombinase with regulated directionality

1 reference

12 December 2020

The minimum internal and external sequence requirements for transposition of the eukaryotic transformation vector piggyBac

1 reference

12 December 2020

A motif in the C-terminal domain of phiC31 integrase controls the directionality of recombination

1 reference

12 December 2020

The role of subterminal sites of transposable element Ds of Zea mays in excision.

1 reference

12 December 2020

Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition

1 reference

12 December 2020

Viral vectors for gene therapy

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12 December 2020

Factors acting on Mos1 transposition efficiency

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12 December 2020

Site-specific gene targeting for gene expression in eukaryotes

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12 December 2020

Progress in cationic lipid-mediated gene transfection: a series of bio-inspired lipids as an example

1 reference

12 December 2020

Conservation of Palindromic and Mirror Motifs within Inverted Terminal Repeats of mariner-like Elements

1 reference

12 December 2020

The nucleoid binding protein H-NS acts as an anti-channeling factor to favor intermolecular Tn10 transposition and dissemination

1 reference

12 December 2020

The transposition frequency of IS1-flanked transposons is a function of their size

1 reference

12 December 2020

Molecular engineering of viral gene delivery vehicles

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12 December 2020

The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver

1 reference

12 December 2020

Analysis of the integration function of the streptomycete bacteriophage φC31

1 reference

12 December 2020

Helper-dependent adenoviral vectors in experimental gene therapy.

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12 December 2020

Retroviral integration and human gene therapy

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12 December 2020

[Epidermal stem cells and ex vivo cutaneous gene therapy: application to xeroderma pigmentosum]

1 reference

12 December 2020

Sequences in attB that affect the ability of phiC31 integrase to synapse and to activate DNA cleavage

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12 December 2020

Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integration

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12 December 2020

Awakening gene therapy with Sleeping Beauty transposons

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12 December 2020

Targeted chromosomal insertion of large DNA into the human genome by a fiber-modified high-capacity adenovirus-based vector system.

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12 December 2020

The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition

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12 December 2020

Factors affecting transposition of the Himar1 mariner transposon in vitro

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12 December 2020

Transposition of plasmid-borne Tn10 elements does not exhibit simple length-dependence

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12 December 2020

Assembly of the Tc1 and mariner transposition initiation complexes depends on the origins of their transposase DNA binding domains

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12 December 2020

Base flipping in tn10 transposition: an active flip and capture mechanism

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12 December 2020

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice

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12 December 2020

Adenoviral vectors for gene transfer and therapy

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12 December 2020

The Tol1 element of medaka fish is transposed with only terminal regions and can deliver large DNA fragments into the chromosomes.

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12 December 2020

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

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12 December 2020

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

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12 December 2020

Gene therapy clinical trials worldwide to 2007--an update.

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12 December 2020

Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors.

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12 December 2020

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

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12 December 2020

IHF modulation of Tn10 transposition: sensory transduction of supercoiling status via a proposed protein/DNA molecular spring

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12 December 2020

Fish transposons and their potential use in aquaculture

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12 December 2020

Reduced germline mobility of a mariner vector containing exogenous DNA: effect of size or site?

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12 December 2020

Transposon-like Correia elements: structure, distribution and genetic exchange between pathogenic Neisseria sp

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12 December 2020

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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12 December 2020

Protein trans-splicing as a means for viral vector-mediated in vivo gene therapy

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12 December 2020

Phi c31 integrase induces chromosomal aberrations in primary human fibroblasts

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12 December 2020

Plant transposable elements: where genetics meets genomics

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12 December 2020

The global bacterial regulator H-NS promotes transpososome formation and transposition in the Tn5 system

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12 December 2020

Gene therapy vectors: the prospects and potentials of the cut-and-paste transposons

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12 December 2020

Integration specificity of phage phiC31 integrase in the human genome

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12 December 2020

Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA.

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12 December 2020

Researchers and regulators reflect on first gene therapy death

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12 December 2020

Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates

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12 December 2020

Genetically manipulated mice: a powerful tool with unsuspected caveats

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12 December 2020

Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome

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12 December 2020

PiggyBac transposon-mediated gene transfer in human cells

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12 December 2020

Nitric oxide synthase gene therapy enhances the toxicity of cisplatin in cancer cells

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12 December 2020

Gene therapy. Therapeutic approaches and implications

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12 December 2020

Gutless adenovirus: last-generation adenovirus for gene therapy

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12 December 2020

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

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12 December 2020

Gene therapy clinical trials worldwide 1989-2004-an overview.

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12 December 2020

Mammalian genomes contain active recombinase recognition sites

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12 December 2020

The positive and negative regulation of Tn10 transposition by IHF is mediated by structurally asymmetric transposon arms

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12 December 2020

Unexpected stability of mariner transgenes in Drosophila

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12 December 2020

The wild-type conformation of the Mos-1 inverted terminal repeats is suboptimal for transposition in bacteria

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12 December 2020

Tn10 transposase acts preferentially on nearby transposon ends in vivo

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12 December 2020

DNA looping and catalysis; the IHF-folded arm of Tn10 promotes conformational changes and hairpin resolution

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12 December 2020

Base-flipping dynamics in a DNA hairpin processing reaction

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12 December 2020

Early intermediates of mariner transposition: catalysis without synapsis of the transposon ends suggests a novel architecture of the synaptic complex

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12 December 2020

Functional genomics of Neisseria meningitidis pathogenesis

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12 December 2020

Small mobile sequences in bacteria display diverse structure/function motifs.

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12 December 2020

Effects of insert size on transposition efficiency of the sleeping beauty transposon in mouse cells

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12 December 2020

Role of the N-terminal domain of phiC31 integrase in attB-attP synapsis.

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12 December 2020

Sustained transgene expression using non-viral enzymatic systems for stable chromosomal integration.

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12 December 2020

Targeted Sleeping Beauty transposition in human cells

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12 December 2020

Nature as a source of inspiration for cationic lipid synthesis.

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12 December 2020

P1 site-specific recombination: nucleotide sequence of the recombining sites

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12 December 2020

Sleeping beauty vector system moves toward human trials in the United States

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12 December 2020

The human SETMAR protein preserves most of the activities of the ancestral Hsmar1 transposase

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12 December 2020

Gene therapy progress and prospects: nonviral vectors.

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12 December 2020

Base flipping in V(D)J recombination: insights into the mechanism of hairpin formation, the 12/23 rule, and the coordination of double-strand breaks

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12 December 2020

Transposition of the human Hsmar1 transposon: rate-limiting steps and the importance of the flanking TA dinucleotide in second strand cleavage.

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12 December 2020

Complete nucleotide sequence of Tn10.

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12 December 2020

Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue

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12 December 2020

Evolution of adenoviruses as gene therapy vectors

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12 December 2020

Tol2: a versatile gene transfer vector in vertebrates

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12 December 2020

The Tol2 transposable element of the medaka fish: an active DNA-based element naturally occurring in a vertebrate genome

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12 December 2020

Promiscuous target interactions in the mariner transposon Himar1

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12 December 2020

Protein-DNA contacts and conformational changes in the Tn10 transpososome during assembly and activation for cleavage

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12 December 2020

Drosophila P element transposase recognizes internal P element DNA sequences.

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12 December 2020

Non-immunostimulatory nonviral vectors

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12 December 2020

Cis requirements for transposition of Tc1-like transposons in C. elegans

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12 December 2020

A capsid-modified helper-dependent adenovirus vector containing the beta-globin locus control region displays a nonrandom integration pattern and allows stable, erythroid-specific gene expression

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12 December 2020

Genetic linkage analysis to identify a gene required for the addition of phosphoethanolamine to meningococcal lipopolysaccharide

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12 December 2020

Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns

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12 December 2020

Cyclic changes in the affinity of protein-DNA interactions drive the progression and regulate the outcome of the Tn10 transposition reaction

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12 December 2020

Birth of a chimeric primate gene by capture of the transposase gene from a mobile element

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12 December 2020

Mutant Mos1 mariner transposons are hyperactive in Aedes aegypti

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12 December 2020

Approaches for generating recombinant adenovirus vectors

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12 December 2020

Somatic integration from an adenoviral hybrid vector into a hot spot in mouse liver results in persistent transgene expression levels in vivo

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12 December 2020

The ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon ends

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12 December 2020

Recent developments in adeno-associated virus vector technology

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12 December 2020

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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12 December 2020

piggyBac internal sequences are necessary for efficient transformation of target genomes

1 reference

12 December 2020

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

1 reference

12 December 2020

10.1007/S10709-009-9434-3

Identifiers

DOI

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21 August 2017

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