(Q37679117)

21 August 2017

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title

Genetic mechanisms of drug resistance. A review (English)

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21 August 2017

Borst P

1

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21 August 2017

publication date

1 January 1991

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21 August 2017

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21 August 2017

volume

30

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21 August 2017

issue

1

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21 August 2017

page(s)

87-105

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Drug-resistance patterns assessed from tumor marker analysis.

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Metaphase chromosome anomaly: association with drug resistance and cell-specific products

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Gene amplification in cultured animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Recent progress in understanding mechanisms of mammalian DNA amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Circular DNA of 3T6R50 double minute chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

DNA content and structure of (double) minutes of a methotrexate-resistant cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Structure of amplified DNA, analyzed by pulsed field gradient gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

DNA amplification is rare in normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Mechanisms of multidrug resistance and implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

The biochemistry of P-glycoprotein-mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Expression of a multidrug-resistance gene in human tumors and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Dominance of colchicine resistance in hybrid CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Expression of the multidrug-resistant gene in hepatocarcinogenesis and regenerating rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Coinduction of MDR-1 multidrug-resistance and cytochrome P-450 genes in rat liver by xenobiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Structure and expression of the human MDR (P-glycoprotein) gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

The multidrug resistance phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Detection of P-glycoprotein in ovarian cancer: a molecular marker associated with multidrug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Detection of a multidrug resistant phenotype in acute non-lymphoblastic leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Correlation of MDR1 gene expression with chemotherapy in neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Prediction of doxorubicin resistance in vitro in myeloma, lymphoma, and breast cancer by P-glycoprotein staining

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Electrophoretic analysis of 248 clinical breast cancer specimens for P-glycoprotein overexpression or gene amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

MDR1 gene expression in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Inhibitors of DNA topoisomerases

21 January 2018

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https://api.crossref.org/works/10.3109%2F02841869109091819

Recent studies of DNA topoisomerases

21 January 2018

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https://api.crossref.org/works/10.3109%2F02841869109091819

DNA topoisomerase poisons as antitumor drugs

21 January 2018

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https://api.crossref.org/works/10.3109%2F02841869109091819

Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Drug resistance and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Glutathione S-transferases: gene structure, regulation, and biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Role of the Glutathione Redox Cycle in Acquired and de Novo Multidrug Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Overexpression of metallothionein confers resistance to anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Elevated expression of thymidylate synthase cycle genes in cisplatin-resistant human ovarian carcinoma A2780 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Systemic resistance to methotrexate in transgenic mice carrying a mutant dihydrofolate reductase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Multidrug resistance during chemical carcinogenesis: a mechanism revealed?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F02841869109091819

10.3109/02841869109091819

21 January 2018

Identifiers

DOI

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21 August 2017

1 reference