(Q37679215)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28253885%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction (English)

1 reference

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4 April 2020

0 references

7

1 reference

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4 April 2020

author name string

Arpeeta Sharma

1

1 reference

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4 April 2020

Luddwi Rizky

2

1 reference

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4 April 2020

Nada Stefanovic

3

1 reference

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4 April 2020

Mitchel Tate

4

1 reference

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4 April 2020

Rebecca H Ritchie

5

1 reference

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4 April 2020

Keith W Ward

6

1 reference

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4 April 2020

language of work or name

English

0 references

publication date

3 March 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28253885%20AND%20SRC:MED&resulttype=core&format=json

Cardiovascular Diabetology

4 April 2020

published in

1 reference

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4 April 2020

volume

16

1 reference

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4 April 2020

issue

1

1 reference

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4 April 2020

page(s)

33

1 reference

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https://scigraph.springernature.com/pub.10.1186/s12933-017-0513-y

4 April 2020

exact match

0 references

cites work

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Sulforaphane attenuation of type 2 diabetes-induced aortic damage was associated with the upregulation of Nrf2 expression and function

23 August 2017

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Endothelial dysfunction in diabetes: pathogenesis, significance, and treatment

23 August 2017

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The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores endothelial function impaired by reduced Nrf2 activity in chronic kidney disease

23 August 2017

1 reference

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Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease

23 August 2017

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Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function

23 August 2017

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Selective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in mice

23 August 2017

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Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

23 August 2017

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Bardoxolone methyl and kidney function in CKD with type 2 diabetes

23 August 2017

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Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1.

23 August 2017

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Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

23 August 2017

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Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications

23 August 2017

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Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes

23 August 2017

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The vicious circle between oxidative stress and inflammation in atherosclerosis.

23 August 2017

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Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice

23 August 2017

1 reference

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Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

23 August 2017

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10-year follow-up of intensive glucose control in type 2 diabetes

23 August 2017

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The HOPE (Heart Outcomes Prevention Evaluation) Study and its consequences

23 August 2017

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Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

23 August 2017

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Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles

23 August 2017

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Nrf2 as an Endothelial Mechanosensitive Transcription Factor: Going With the Flow

23 August 2017

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Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl

6 September 2017

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Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much?

6 September 2017

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6 September 2017

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Anti-atherogenic effect of laminar shear stress via Nrf2 activation

6 September 2017

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6 September 2017

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Caffeic acid phenethyl ester-mediated Nrf2 activation and IkappaB kinase inhibition are involved in NFkappaB inhibitory effect: structural analysis for NFkappaB inhibition

6 September 2017

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Rationale and trial design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: the Occurrence of Renal Events (BEACON).

14 September 2017

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Nitric oxide synthesis is reduced in subjects with type 2 diabetes and nephropathy.

25 June 2018

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NF-kappaB, Nrf2, and HO-1 interplay in redox-regulated VCAM-1 expression

25 June 2018

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Measurement of NAD(P)H oxidase-derived superoxide with the luminol analogue L-012.

25 June 2018

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Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice

25 June 2018

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A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy.

25 June 2018

1 reference

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Lack of glutathione peroxidase-1 facilitates a pro-inflammatory and activated vascular endothelium.

1 September 2018

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Revision of instructions to authors for pharmacology research and perspectives: enhancing the quality and transparency of published work

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

The absence of macrophage Nrf2 promotes early atherogenesis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

Nrf2 is a critical modulator of the innate immune response in a model of uveitis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5335831

Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12933-017-0513-Y

Lack of the Antioxidant Enzyme Glutathione Peroxidase-1 Accelerates Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice

21 January 2018

1 reference

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https://api.crossref.org/works/10.1186%2FS12933-017-0513-Y

Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress

21 January 2018

1 reference

12 December 2020

A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases

1 reference

12 December 2020

A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice

1 reference

12 December 2020

Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD

1 reference

12 December 2020

Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression

1 reference

12 December 2020

10.1186/S12933-017-0513-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28253885%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28253885%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

28253885

1 reference