(Q37680961)

21 August 2017

1 reference

title

Patented inhibitors of p53-Mdm2 interaction (2006 - 2008). (English)

1 reference

21 August 2017

0 references

Lutz Weber

1

1 reference

PubMed ID

20100001

21 August 2017

language of work or name

English

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publication date

1 February 2010

1 reference

Expert Opinion on Therapeutic Patents

21 August 2017

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21 August 2017

20

1 reference

21 August 2017

2

1 reference

21 August 2017

179-191

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T antigen is bound to a host protein in SY40-transformed cells

21 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Cancer. p53, guardian of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Targeting protein-protein interactions for therapeutic intervention: a challenge for the future.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Patented small molecule inhibitors of p53-MDM2 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Inactivation of the p53 pathway in retinoblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Small molecular weight protein-protein interaction antagonists: an insurmountable challenge?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Isoquinolin-1-one inhibitors of the MDM2-p53 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903514129

10.1517/13543770903514129

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference

PubMed ID

20100001