(Q37683456)

22 August 2017

Age-related epigenetic drift in the pathogenesis of MDS and AML. (English)

1 reference

22 August 2017

0 references

2

Sheryl M Gough

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Yue Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ryan J. Castoro

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ryan J. Castoro

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Marcos Estecio

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

12

Peter D Aplan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jean-Pierre J Issa

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Shinji Maegawa

1

1 reference

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31 May 2020

Naoko Watanabe-Okochi

3

1 reference

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31 May 2020

Nianxiang Zhang

5

1 reference

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31 May 2020

Jaroslav Jelinek

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Shoudan Liang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Toshio Kitamura

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

10 January 2014

1 reference

22 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

580-591

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

31 May 2020

cites work

1 reference

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Dynamic DNA methylation across diverse human cell lines and tissues

23 August 2017

1 reference

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The epigenome of AML stem and progenitor cells

23 August 2017

1 reference

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Genome-wide methylation profiles reveal quantitative views of human aging rates

23 August 2017

1 reference

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Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique

23 August 2017

1 reference

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Aging effects on DNA methylation modules in human brain and blood tissue

23 August 2017

1 reference

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The role of mutations in epigenetic regulators in myeloid malignancies

23 August 2017

1 reference

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Comprehensive molecular characterization of human colon and rectal cancer

23 August 2017

1 reference

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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

23 August 2017

1 reference

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Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia

23 August 2017

1 reference

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Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome

23 August 2017

1 reference

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DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory

23 August 2017

1 reference

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Dnmt3a is essential for hematopoietic stem cell differentiation

23 August 2017

1 reference

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Frequent pathway mutations of splicing machinery in myelodysplasia

23 August 2017

1 reference

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Clinical effect of point mutations in myelodysplastic syndromes

23 August 2017

1 reference

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Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

23 August 2017

1 reference

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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

23 August 2017

1 reference

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Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer

23 August 2017

1 reference

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Current and future management options for myelodysplastic syndromes

23 August 2017

1 reference

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Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Epigenetic changes in the myelodysplastic syndrome.

23 August 2017

1 reference

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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

23 August 2017

1 reference

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Widespread and tissue specific age-related DNA methylation changes in mice.

23 August 2017

1 reference

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DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes

23 August 2017

1 reference

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TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

23 August 2017

1 reference

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DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma

23 August 2017

1 reference

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Acquired mutations in TET2 are common in myelodysplastic syndromes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse

23 August 2017

1 reference

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Computational and experimental identification of novel human imprinted genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

High-throughput methylation profiling by MCA coupled to CpG island microarray

23 August 2017

1 reference

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Gene silencing by DNA methylation in haematological malignancies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

The epigenomics of cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Epigenetic stem cell signature in cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Control of developmental regulators by Polycomb in human embryonic stem cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Polycomb complexes repress developmental regulators in murine embryonic stem cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Aberrant methylations in cancer cells: where do they come from?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

A census of human cancer genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Worms gang up on bacteria

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

CpG island methylation in colorectal adenomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Aging, methylation and cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

CpG island methylator phenotypes in aging and cancer.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Number of CpG islands and genes in human and mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Mutations in epigenetic regulators in myelodysplastic syndromes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Genetics of myelodysplastic syndromes: new insights

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Frequent epigenetic silencing of protocadherin 10 by methylation in multiple haematologic malignancies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation analysis of primary tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Methylation of polycomb target genes in intestinal cancer is mediated by inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

AML1 mutations induced MDS and MDS/AML in a mouse BMT model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

DNA methylation and developmental genes in lymphomagenesis--more questions than answers?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

DNA methylation dynamics during in vivo differentiation of blood and skin stem cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

High frequency of p16(INK4A) promoter methylation in NRAS-mutated cutaneous melanoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Methylation at mouse Cdkn1c is acquired during postimplantation development and functions to maintain imprinted expression.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Accelerated age-related CpG island methylation in ulcerative colitis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

Methylation profiling in acute myeloid leukemia.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975058

CpG island methylator phenotype in cancer

1 September 2018

1 reference

12 December 2020

CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine

1 reference

12 December 2020

New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients

1 reference

12 December 2020

Epigenetic profile in chronic lymphocytic leukemia using methylation-specific multiplex ligation-dependent probe amplification

1 reference

12 December 2020

Evidence for erosion of mouse CpG islands during mammalian evolution

1 reference

12 December 2020

Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis

1 reference

12 December 2020

The fundamental role of epigenetic events in cancer

1 reference

12 December 2020

Identifiers

DOI

10.1101/GR.157529.113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

24414704

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24414704%20AND%20SRC:MED&resulttype=core&format=json