(Q37683527)

English

Antimicrobial nucleoside antibiotics targeting cell wall assembly: recent advances in structure-function studies and nucleoside biosynthesis

scientific article published on 16 December 2009

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scholarly article

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Europe PubMed Central

22 August 2017

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Europe PubMed Central

Antimicrobial nucleoside antibiotics targeting cell wall assembly: recent advances in structure-function studies and nucleoside biosynthesis (English)

1 reference

Europe PubMed Central

22 August 2017

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based on heuristic

inferred from title

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object named as

Rebecca J M Goss

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author name string

Michael Winn

1

1 reference

Europe PubMed Central

22 August 2017

Rebecca J M Goss

2

1 reference

Europe PubMed Central

22 August 2017

Ken-ichi Kimura

3

1 reference

Europe PubMed Central

22 August 2017

Timothy D H Bugg

4

1 reference

Europe PubMed Central

22 August 2017

publication date

16 December 2009

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Europe PubMed Central

22 August 2017

Natural Product Reports

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Europe PubMed Central

22 August 2017

27

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Europe PubMed Central

22 August 2017

2

1 reference

Europe PubMed Central

22 August 2017

279-304

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Europe PubMed Central

22 August 2017

Antibacterial discovery and development--the failure of success?

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Drugs for bad bugs: confronting the challenges of antibacterial discovery

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Why is big Pharma getting out of antibacterial drug discovery?

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Intracellular steps of bacterial cell wall peptidoglycan biosynthesis: enzymology, antibiotics, and antibiotic resistance

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Recent advances in the formation of the bacterial peptidoglycan monomer unit

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

The biosynthesis of peptidoglycan lipid-linked intermediates

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

In vitro assembly of a complete, pentaglycine interpeptide bridge containing cell wall precursor (lipid II-Gly5) of Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Chemistry and biology of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Glycopeptide and lipoglycopeptide antibiotics

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Modeling bacterial UDP-HexNAc: polyprenol-P HexNAc-1-P transferases

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Topological analysis of the MraY protein catalysing the first membrane step of peptidoglycan synthesis.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Purification and characterization of the bacterial MraY translocase catalyzing the first membrane step of peptidoglycan biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Phospho-N-acetyl-muramyl-pentapeptide translocase from Escherichia coli: catalytic role of conserved aspartic acid residues

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Genetic evidence that the bacteriophage phi X174 lysis protein inhibits cell wall synthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

The lysis protein E of phi X174 is a specific inhibitor of the MraY-catalyzed step in peptidoglycan synthesis.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Interaction of the transmembrane domain of lysis protein E from bacteriophage phiX174 with bacterial translocase MraY and peptidyl-prolyl isomerase SlyD.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Purification and functional characterization of phiX174 lysis protein E.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

The cell wall: a carbohydrate armour for the fungal cell

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Cell wall assembly in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Antibiotic resistance versus small molecules, the chemical evolution

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Stereochemical elucidation and total synthesis of dihydropacidamycin D, a semisynthetic pacidamycin

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis of base-modified dihydropacidamycins

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthetic dihydropacidamycin antibiotics: a modified spectrum of activity for the pacidamycin class

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

New pacidamycin antibiotics through precursor-directed biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Sansanmycins B and C, new components of sansanmycins.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis and activity of 5'-uridinyl dipeptide analogues mimicking the amino terminal peptide chain of nucleoside antibiotic mureidomycin A.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

A solid-phase approach to analogues of the antibiotic mureidomycin

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Caprazamycins, novel lipo-nucleoside antibiotics, from Streptomyces sp. II. Structure elucidation of caprazamycins

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Fine synthetic nucleoside chemistry based on nucleoside natural products synthesis.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Identification and manipulation of the caprazamycin gene cluster lead to new simplified liponucleoside antibiotics and give insights into the biosynthetic pathway

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Assignment of the liposidomycin diazepanone stereochemistry.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis of the nucleoside moiety of liposidomycins: elucidation of the pharmacophore of this family of MraY inhibitors

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis of analogues of the O-beta-D-ribofuranosyl nucleoside moiety of liposidomycins. Part 1: contribution of the amino group and the uracil moiety upon the inhibition of MraY.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis of analogues of the O-beta-D-ribofuranosyl nucleoside moiety of liposidomycins. Part 2: role of the hydroxyl groups upon the inhibition of MraY.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis of sub-micromolar inhibitors of MraY by exploring the region originally occupied by the diazepanone ring in the liposidomycin structure

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Development of a highly beta-selective ribosylation reaction without using neighboring group participation: total synthesis of (+)-caprazol, a core structure of caprazamycins

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Design and synthesis of diketopiperazine and acyclic analogs related to the caprazamycins and liposidomycins as potential antibacterial agents.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Structure-activity relationship of truncated analogs of caprazamycins as potential anti-tuberculosis agents

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis of caprazamycin analogues and their structure--activity relationship for antibacterial activity.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis and antimycobacterial activity of capuramycin analogues. Part 1: substitution of the azepan-2-one moiety of capuramycin

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Synthesis and antimycobacterial activity of capuramycin analogues. Part 2: acylated derivatives of capuramycin-related compounds

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Activity of capuramycin analogues against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium intracellulare in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

In vitro antimycobacterial activities of capuramycin analogues

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Conformational analysis of chirally deuterated tunicamycin as an active site probe of UDP-N-acetylhexosamine:polyprenol-P N-acetylhexosamine-1-P translocases

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Novel inhibitory action of tunicamycin homologues suggests a role for dynamic protein fatty acylation in growth cone-mediated neurite extension

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of their derivatives

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Muraymycins, novel peptidoglycan biosynthesis inhibitors: synthesis and SAR of their analogues

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Metabolic products of microorganisms 181. Chitin synthase from fungi, a test model for substances with insecticidal properties

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Recent advances in antifungal agents

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Cloning and heterologous expression of the entire set of structural genes for nikkomycin synthesis from Streptomyces tendae Tü901 in Streptomyces lividans

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Cloning, sequencing, and function of sanF: A gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Molecular characterization of co-transcribed genes from Streptomyces tendae Tü901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

The Streptomyces tendae Tü901 L-lysine 2-aminotransferase catalyzes the initial reaction in nikkomycin D biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Nikkomycin biosynthesis: formation of a 4-electron oxidation product during turnover of NikD with its physiological substrate

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

A mobile tryptophan is the intrinsic charge transfer donor in a flavoenzyme essential for nikkomycin antibiotic biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Identification and characterization of sanH and sanI involved in the hydroxylation of pyridyl residue during nikkomycin biosynthesis in Streptomyces ansochromogenes

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Molecular characterization of two genes from Streptomyces tendae Tü901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

SanT, a bidomain protein, is essential for nikkomycin biosynthesis of Streptomyces ansochromogenes.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI

1 reference

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21 January 2018

3'-Enolpyruvyl-UMP, a novel and unexpected metabolite in nikkomycin biosynthesis

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H

1 reference

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21 January 2018

Biosynthesis of the tunicamycins: a review

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21 January 2018

The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A.

1 reference

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21 January 2018

Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196.

1 reference

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21 January 2018

Identification of a novel beta-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A.

1 reference

https://api.crossref.org/works/10.1039%2FB816215H

21 January 2018

Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster

1 reference

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21 January 2018

Caprazamycin B, a novel anti-tuberculosis antibiotic, from Streptomyces sp.

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12 April 2024

Studies on Novel Bacterial Translocase I Inhibitors, A-500359s. III. Deaminocaprolactam Derivatives of Capuramycin: A-500359 E, F, H, M-1 and M-2.

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12 April 2024

Studies on novel bacterial translocase I inhibitors, A-500359s. I. Taxonomy, fermentation, isolation, physico-chemical properties and structure elucidation of A-500359 A, C, D and G.

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New pacidamycins produced by Streptomyces coeruleorubidus, NRRL 18370.

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New types of liposidomycins that inhibit bacterial peptidoglycan synthesis and are produced by Streptomyces. II. Isolation and structure elucidation.

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Metabolic products of microorganisms. 263. Nikkomycins SZ, SX, SoZ and SoX, new intermediates associated to the nikkomycin biosynthesis of Streptomyces tendae

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Isolation of Streptomyces tendae mutants with an altered nikkomycin spectrum

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Mureidomycins A-D, novel peptidylnucleoside antibiotics with spheroplast forming activity. II. Structural elucidation

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Mureidomycins A-D, novel peptidylnucleoside antibiotics with spheroplast forming activity. I. Taxonomy, fermentation, isolation and physico-chemical properties.

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Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. II. Isolation and structural elucidation

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Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. I. Taxonomy of the producing organism and fermentation.

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12 April 2024

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Tunicamycin, a new antibiotic. I. Isolation and characterization of tunicamycin.

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New Types of Liposidomycins Which Inhibit Bacterial Peptidoglycan Synthesis Produced by Streptomyces.

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Identifiers

10.1039/B816215H

1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

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