(Q37683772)

22 August 2017

1 reference

title

Anti-chemokine small molecule drugs: a promising future? (English)

1 reference

22 August 2017

Amanda E I Proudfoot

1

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22 August 2017

Christine A Power

series ordinal

2

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22 August 2017

Matthias K Schwarz

series ordinal

3

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22 August 2017

language of work or name

English

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publication date

1 March 2010

1 reference

Expert Opinion on Investigational Drugs

22 August 2017

published in

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22 August 2017

volume

19

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22 August 2017

issue

3

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22 August 2017

page(s)

345-355

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Chemokines--chemotactic cytokines that mediate inflammation

22 August 2017

cites work

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Chemokines and leukocyte traffic

21 January 2018

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Chemokines and chemokine receptors: an overview.

21 January 2018

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Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

21 January 2018

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MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.

21 January 2018

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Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

21 January 2018

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Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

21 January 2018

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Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

21 January 2018

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21 January 2018

Chemokines and disease

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Chemokine receptors: multifaceted therapeutic targets

21 January 2018

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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

1 reference

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A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

21 January 2018

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Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: a pilot study

21 January 2018

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Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

21 January 2018

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A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis

21 January 2018

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Modulation of CCR2 in rheumatoid arthritis: a double-blind, randomized, placebo-controlled clinical trial

21 January 2018

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Chemokine receptor antagonists: overcoming developmental hurdles

21 January 2018

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Hepatotoxicity observed in clinical trials of aplaviroc (GW873140)

21 January 2018

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CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis.

21 January 2018

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Exacerbations of multiple sclerosis in patients treated with gamma interferon

21 January 2018

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Structure function differences in nonpeptide CCR1 antagonists for human and mouse CCR1.

21 January 2018

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Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1

21 January 2018

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Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344.

21 January 2018

1 reference

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The human specific CCR1 antagonist CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice

21 January 2018

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Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis

21 January 2018

1 reference

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Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Proteolytic activation of alternative CCR1 ligands in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Inhibition of fractalkine ameliorates murine collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Structure and Functional Expression of a Human Interleukin-8 Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Identification of a major co-receptor for primary isolates of HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

21 January 2018

1 reference

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Molecular cloning and functional expression of a new human CC-chemokine receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

21 January 2018

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New therapeutics that modulate chemokine networks

21 January 2018

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Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

21 January 2018

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Design, synthesis, and discovery of a novel CCR1 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

The toxicology of chemokine inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Review of progressive multifocal leukoencephalopathy and natalizumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Blockade of chemokine signaling in patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903535867

10.1517/13543780903535867

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference