(Q37687548)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Ryanodine receptor mutations in arrhythmia: The continuing mystery of channel dysfunction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Saptarshi Mukherjee

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Alan J Williams

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Chloé Maxwell

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

2 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

584

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

2153-2160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132818%20AND%20SRC:MED&resulttype=core&format=json

Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia

17 January 2020

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The RYR2-encoded ryanodine receptor/calcium release channel in patients diagnosed previously with either catecholaminergic polymorphic ventricular tachycardia or genotype negative, exercise-induced long QT syndrome: a comprehensive open reading [...]

21 January 2018

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Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies

21 January 2018

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Common sodium channel promoter haplotype in asian subjects underlies variability in cardiac conduction.

21 January 2018

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SCN5A polymorphism restores trafficking of a Brugada syndrome mutation on a separate gene.

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Composite polymorphisms in the ryanodine receptor 2 gene associated with arrhythmogenic right ventricular cardiomyopathy.

21 January 2018

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Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2)

21 January 2018

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Loss of luminal Ca2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death

21 January 2018

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21 January 2018

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Search for cardiac calcium cycling gene mutations in familial ventricular arrhythmias resembling catecholaminergic polymorphic ventricular tachycardia.

21 January 2018

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Cardiac excitation-contraction coupling

21 January 2018

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Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right

21 January 2018

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Beta-adrenergic receptor signaling in the heart: role of CaMKII.

21 January 2018

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PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

21 January 2018

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FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death

21 January 2018

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Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.

21 January 2018

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Mechanisms of Disease: ryanodine receptor defects in heart failure and fatal arrhythmia.

21 January 2018

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Defective cardiac ryanodine receptor regulation during atrial fibrillation

21 January 2018

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PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure

21 January 2018

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Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak

21 January 2018

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Characterization of Recombinant Skeletal Muscle (Ser-2843) and Cardiac Muscle (Ser-2809) Ryanodine Receptor Phosphorylation Mutants

21 January 2018

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Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).

21 January 2018

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Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes

21 January 2018

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Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death

21 January 2018

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Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia

21 January 2018

1 reference

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Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy.

21 January 2018

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Functional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death.

21 January 2018

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Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts

21 January 2018

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Adrenergic regulation of cardiac contractility does not involve phosphorylation of the cardiac ryanodine receptor at serine 2808

21 January 2018

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Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias

21 January 2018

1 reference

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The relative relevance of phosphorylation of the Thr(17) residue of phospholamban is different at different levels of beta-adrenergic stimulation

21 January 2018

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Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway

21 January 2018

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Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase

21 January 2018

1 reference

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Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation

21 January 2018

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Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor

21 January 2018

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Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure

21 January 2018

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Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy

21 January 2018

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Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart

21 January 2018

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Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice.

21 January 2018

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Cardiac oxidative stress in acute and chronic isoproterenol-infused rats

21 January 2018

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FKBP12.6 binding of ryanodine receptors carrying mutations associated with arrhythmogenic cardiac disease

21 January 2018

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Redox modification of ryanodine receptors contributes to sarcoplasmic reticulum Ca2+ leak in chronic heart failure.

21 January 2018

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A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation

21 January 2018

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A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptors

21 January 2018

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The RyR2 central domain peptide DPc10 lowers the threshold for spontaneous Ca2+ release in permeabilized cardiomyocytes.

21 January 2018

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Reducing ryanodine receptor open probability as a means to abolish spontaneous Ca2+ release and increase Ca2+ transient amplitude in adult ventricular myocytes.

21 January 2018

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RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR)

21 January 2018

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Enhanced basal activity of a cardiac Ca2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death

21 January 2018

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Differential Ca2+ sensitivity of RyR2 mutations reveals distinct mechanisms of channel dysfunction in sudden cardiac death.

21 January 2018

1 reference

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Abnormal calcium signaling and sudden cardiac death associated with mutation of calsequestrin

21 January 2018

1 reference

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A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

Protein protein interactions between triadin and calsequestrin are involved in modulation of sarcoplasmic reticulum calcium release in cardiac myocytes

21 January 2018

1 reference

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Intra-sarcoplasmic reticulum Ca2+ oscillations are driven by dynamic regulation of ryanodine receptor function by luminal Ca2+ in cardiomyocytes

21 January 2018

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New roles of calsequestrin and triadin in cardiac muscle.

21 January 2018

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Beta-adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel

21 January 2018

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Coupled gating between cardiac calcium release channels (ryanodine receptors).

21 January 2018

1 reference

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Role of coupled gating between cardiac ryanodine receptors in the genesis of triggered arrhythmias

21 January 2018

1 reference

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Peptide probe study of the critical regulatory domain of the cardiac ryanodine receptor

21 January 2018

1 reference

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A domain peptide of the cardiac ryanodine receptor regulates channel sensitivity to luminal Ca2+ via cytoplasmic Ca2+ sites

21 January 2018

1 reference

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Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor

21 January 2018

1 reference

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Localization of a disease-associated mutation site in the three-dimensional structure of the cardiac muscle ryanodine receptor

21 January 2018

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Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains.

21 January 2018

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Arrhythmogenic mutation-linked defects in ryanodine receptor autoregulation reveal a novel mechanism of Ca2+ release channel dysfunction

21 January 2018

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Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia.

21 January 2018

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Sudden cardiac death despite an implantable cardioverter-defibrillator in a young female with catecholaminergic ventricular tachycardia.

21 January 2018

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Sudden death in a young man with catecholaminergic polymorphic ventricular tachycardia and paroxysmal atrial fibrillation

21 January 2018

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Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia

21 January 2018

1 reference

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Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association

21 January 2018

1 reference

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A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201.

21 January 2018

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Pharmacological characteristics and clinical applications of K201.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts

21 January 2018

1 reference

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Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

21 January 2018

1 reference

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Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.057

Calcium channel antagonism reduces exercise-induced ventricular arrhythmias in catecholaminergic polymorphic ventricular tachycardia patients with RyR2 mutations

21 January 2018

1 reference

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Direct binding of verapamil to the ryanodine receptor channel of sarcoplasmic reticulum

21 January 2018

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Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

21 January 2018

1 reference

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Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.

21 January 2018

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Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial

21 January 2018

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Catecholaminergic polymorphic ventricular tachycardia: electrocardiographic characteristics and optimal therapeutic strategies to prevent sudden death

21 January 2018

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Therapeutic strategies for long-QT syndrome: does the molecular substrate matter?

21 January 2018

1 reference

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Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations

21 January 2018

1 reference

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