(Q37688651)

English

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

scientific article published on April 1996

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scholarly article

1 reference

Europe PubMed Central

22 August 2017

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions (English)

1 reference

Europe PubMed Central

22 August 2017

0 references

amyotrophic lateral sclerosis

0 references

0 references

John Q. Trojanowski

5

object named as

Trojanowski JQ

1 reference

Europe PubMed Central

22 August 2017

author name string

Tu PH

1

1 reference

Europe PubMed Central

22 August 2017

Raju P

2

1 reference

Europe PubMed Central

22 August 2017

Robinson KA

3

1 reference

Europe PubMed Central

22 August 2017

Gurney ME

4

1 reference

Europe PubMed Central

22 August 2017

Lee VM

6

1 reference

Europe PubMed Central

22 August 2017

language of work or name

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publication date

1 April 1996

1 reference

Europe PubMed Central

22 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

22 August 2017

93

1 reference

Europe PubMed Central

22 August 2017

7

1 reference

Europe PubMed Central

22 August 2017

3155-3160

1 reference

Europe PubMed Central

22 August 2017

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Molecular phenotype of simian virus 40 large T antigen-induced primitive neuroectodermal tumors in four different lines of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Comparison of sporadic and familial disease amongst 580 cases of motor neuron disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Some neural intermediate filaments contain both peripherin and the neurofilament proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Cytopathology of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

The molecular biology of intermediate filament proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 August 2017

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

14 September 2017

Electrophysiologic studies in the diagnosis and prognosis of motor neuron diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

14 September 2017

Ubiquitin in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

28 September 2017

Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

28 September 2017

Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

28 September 2017

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 June 2018

Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 June 2018

Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 June 2018

Monoclonal Antibodies to Gel-Excised Glial Filament Protein and Their Reactivities with Other Intermediate Filament Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 June 2018

Alpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

23 June 2018

SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

1 September 2018

Interaction of the tail domain of high molecular weight subunits of neurofilaments with the COOH-terminal region of tubulin and its regulation by tau protein kinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

1 September 2018

Reactive astrocytes are widespread in the cortical gray matter of amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

1 September 2018

Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=39778

1 September 2018

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal mossy fiber changes in mice transgenic for the human copper-zinc superoxide dismutase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down's syndrome: Abnormal neuromuscular junction in tongue of transgenic mice with elevated levels of human Cu/Zn-superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylated high molecular weight neurofilament protein in lower motor neurons in amyotrophic lateral sclerosis and other neurodegenerative diseases involving ventral horn cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down's syndrome: morphological remodelling and increased complexity in the neuromuscular junction of transgenic CuZn-superoxide dismutase mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural study of skein-like inclusions in anterior horn neurons of patients with motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripherin immunoreactive structures in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary axonal swellings and amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin and neurofilament expression in anterior horn cells in amyotrophic lateral sclerosis: possible clues to the pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper/zinc superoxide dismutase mRNA levels are increased in sporadic amyotrophic lateral sclerosis motorneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/8610185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.93.7.3155

1 reference

Europe PubMed Central

22 August 2017

1996PNAS...93.3155T

0 references

1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

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