(Q37690081)

English

Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways

scientific article published on 22 August 2013

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scholarly article

1 reference

Europe PubMed Central

22 August 2017

Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways (English)

1 reference

Europe PubMed Central

22 August 2017

0 references

toll-like receptor

0 references

intervertebral disc cell

1 reference

based on heuristic

inferred from title

object named as

Karin Wuertz

10

0 references

Michael O Hottiger

object named as

Michael O Hottiger

9

0 references

Jonathan P. Sleeman

object named as

Jonathan Sleeman

5

0 references

author name string

Lilian Quero

1

1 reference

Europe PubMed Central

22 August 2017

Marina Klawitter

2

1 reference

Europe PubMed Central

22 August 2017

Anja Schmaus

3

1 reference

Europe PubMed Central

22 August 2017

Melanie Rothley

4

1 reference

Europe PubMed Central

22 August 2017

André N Tiaden

6

1 reference

Europe PubMed Central

22 August 2017

Juergen Klasen

7

1 reference

Europe PubMed Central

22 August 2017

Norbert Boos

8

1 reference

Europe PubMed Central

22 August 2017

Peter J Richards

11

1 reference

Europe PubMed Central

22 August 2017

publication date

22 August 2013

1 reference

Europe PubMed Central

22 August 2017

Arthritis Research and Therapy

1 reference

Europe PubMed Central

22 August 2017

15

1 reference

Europe PubMed Central

22 August 2017

R94

1 reference

Europe PubMed Central

22 August 2017

4

1 reference

Europe PubMed Central

22 August 2017

https://scigraph.springernature.com/pub.10.1186/ar4274

0 references

Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Increased hyaluronan fragmentation during pulmonary ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Pattern recognition receptors and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Matrix metalloproteinase expression levels suggest distinct enzyme roles during lumbar disc herniation and degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Hyaluronan-mediated angiogenesis in vascular disease: uncovering RHAMM and CD44 receptor signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Hyaluronan fragments act as an endogenous danger signal by engaging TLR2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Extracellular matrix in disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

A fibronectin fragment alters the metabolism by rabbit intervertebral disc cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

The role of interleukin-6 in nociception and pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Hyaluronan and its catabolic products in tissue injury and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Hyal2--less active, but more versatile?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Interleukin-8 as a mediator of sympathetic pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 August 2017

Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

6 September 2017

Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

14 September 2017

Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

14 September 2017

Hyaluronan oligosaccharide treatment of chondrocytes stimulates expression of both HAS-2 and MMP-3, but by different signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 June 2018

Effect of a Type II Collagen Fragment on the Expression of Genes of the Extracellular Matrix in Cells of the Intervertebral Disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 June 2018

p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 June 2018

Hyaluronan fragments activate nitric oxide synthase and the production of nitric oxide by articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 June 2018

Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

23 June 2018

Small hyaluronan oligosaccharides induce inflammation by engaging both toll-like-4 and CD44 receptors in human chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

1 September 2018

Differential effect of molecular size HA in mouse chondrocytes stimulated with PMA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

1 September 2018

Role of TNF-alpha in sensitization of nociceptive dorsal horn neurons induced by application of nucleus pulposus to L5 dorsal root ganglion in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

1 September 2018

Hyaluronan-oligosaccharide-induced transcription of metalloproteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

1 September 2018

Matrix metalloproteinases: the clue to intervertebral disc degeneration?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978638

1 September 2018

The effects of collagen fragments on the extracellular matrix metabolism of bovine and human chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low back pain in relation to lumbar disc degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cross-sectional study correlating lumbar spine degeneration with disability and pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibronectin fragment activation of ERK increasing integrin α₅ and β₁ subunit expression to degenerate nucleus pulposus cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical changes in intervertebral disc degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraarticular injection of fibronectin fragments causes severe depletion of cartilage proteoglycans in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/23968377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

Europe PubMed Central

22 August 2017

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1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

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