(Q37690581)

22 August 2017

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title

Progress and prospects: Immunobiology of gene therapy for neurodegenerative disease: prospects and risks (English)

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22 August 2017

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M M McMenamin

1

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22 August 2017

M J A Wood

series ordinal

2

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22 August 2017

language of work or name

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11 February 2010

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22 August 2017

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22 August 2017

volume

17

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22 August 2017

issue

4

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22 August 2017

page(s)

448-458

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https://scigraph.springernature.com/pub.10.1038/gt.2010.2

22 August 2017

exact match

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cites work

What is immune privilege (not)?

1 reference

What is the blood-brain barrier (not)?

21 January 2018

1 reference

Neuroprotective role of the innate immune system by microglia

21 January 2018

1 reference

Stress primes microglia to the presence of systemic inflammation: implications for environmental influences on the brain.

21 January 2018

1 reference

Microglial physiology: unique stimuli, specialized responses

21 January 2018

1 reference

In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain

21 January 2018

1 reference

Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia

21 January 2018

1 reference

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

21 January 2018

1 reference

Sensing of viral infection and activation of innate immunity by toll-like receptor 3

21 January 2018

1 reference

Molecular basis for detection of invading pathogens in the brain.

21 January 2018

1 reference

T cells' immunological synapses induce polarization of brain astrocytes in vivo and in vitro: a novel astrocyte response mechanism to cellular injury

21 January 2018

1 reference

Infiltrating CTLs in human glioblastoma establish immunological synapses with tumorigenic cells

21 January 2018

1 reference

CD8+ T cells in inflammatory demyelinating disease.

21 January 2018

1 reference

The relation between inflammation and neurodegeneration in multiple sclerosis brains.

21 January 2018

1 reference

Preferential activation of Toll-like receptor nine by CD46-utilizing adenoviruses

21 January 2018

1 reference

Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

21 January 2018

1 reference

Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors.

21 January 2018

1 reference

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

21 January 2018

1 reference

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

21 January 2018

1 reference

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

The interferon-induced expression of APOBEC3G in human blood-brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to central nervous system

21 January 2018

1 reference

Viral and cellular microRNAs as determinants of viral pathogenesis and immunity

21 January 2018

1 reference

Silencing Viral MicroRNA as a Novel Antiviral Therapy?

21 January 2018

1 reference

Cellular versus viral microRNAs in host-virus interaction

21 January 2018

1 reference

Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease

21 January 2018

1 reference

21 January 2018

1 reference

Mechanisms of inflammation induced tissue injury in multiple sclerosis

21 January 2018

1 reference

Role of the innate immune system in autoimmune inflammatory demyelination

21 January 2018

1 reference

CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?

21 January 2018

1 reference

Recent patents in CNS drug discovery: the management of inflammation in the central nervous system

21 January 2018

1 reference

Regulation of innate immune responses in the brain

21 January 2018

1 reference

Does neuroinflammation fan the flame in neurodegenerative diseases?

21 January 2018

1 reference

Central inhibition of interleukin-1beta ameliorates sickness behavior in aged mice.

21 January 2018

1 reference

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

21 January 2018

1 reference

Peripheral cytokines profile in Parkinson's disease.

21 January 2018

1 reference

Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: an age-related selective uptake with reversal of learning impairment

21 January 2018

1 reference

Time-course of blood-brain barrier disruption in senescence-accelerated mouse prone 8 (SAMP8) mice.

21 January 2018

1 reference

Immune blood biomarkers of Alzheimer disease patients.

21 January 2018

1 reference

Immune defects in Alzheimer's disease: new medications development

21 January 2018

1 reference

ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage.

21 January 2018

1 reference

Age and neuroinflammation: a lifetime of psychoneuroimmune consequences

21 January 2018

1 reference

Relationship of varying patterns of cytokine production to the anorexic and neuroendocrine effects of repeated Staphylococcal enterotoxin A exposure

21 January 2018

1 reference

Influence of age on behavioral, immune and endocrine responses to the T-cell superantigen staphylococcal enterotoxin A.

21 January 2018

1 reference

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.

21 January 2018

1 reference

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines

21 January 2018

1 reference

Readministration of adenoviral gene delivery to dopamine neurons.

21 January 2018

1 reference

Th1 cytokines are upregulated by adenoviral vectors in the brains of primed mice.

21 January 2018

1 reference

Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the cell biology of neuroimmune interactions

21 January 2018

1 reference

Viral vectors for in vivo gene transfer in Parkinson's disease: properties and clinical grade production.

21 January 2018

1 reference

Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response

21 January 2018

1 reference

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

21 January 2018

1 reference

Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys

21 January 2018

1 reference

Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial

21 January 2018

1 reference

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

21 January 2018

1 reference

Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease

21 January 2018

1 reference

Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.

21 January 2018

1 reference

Development and applications of non-HIV-based lentiviral vectors in neurological disorders

21 January 2018

1 reference

In vivo manipulation of gene expression in non-human primates using lentiviral vectors as delivery vehicles

21 January 2018

1 reference

Applications of lentiviral vectors for biology and gene therapy of neurological disorders.

21 January 2018

1 reference

Activation of transgene-specific T cells following lentivirus-mediated gene delivery to mouse lung

21 January 2018

1 reference

Immunization with a lentivector that targets tumor antigen expression to dendritic cells induces potent CD8+ and CD4+ T-cell responses

21 January 2018

1 reference

Lentivector immunization stimulates potent CD8 T cell responses against melanoma self-antigen tyrosinase-related protein 1 and generates antitumor immunity in mice.

21 January 2018

1 reference

One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: clinical implications.

21 January 2018

1 reference

Striatal readministration of rAAV vectors reveals an immune response against AAV2 capsids that can be circumvented.

21 January 2018

1 reference

Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery

21 January 2018

1 reference

Immunization against the transgene but not the TetON switch reduces expression from gutless adenoviral vectors in the brain

21 January 2018

1 reference

Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1

21 January 2018

1 reference

Immune response to helper dependent adenoviral mediated liver gene therapy: challenges and prospects.

21 January 2018

1 reference

Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors.

21 January 2018

1 reference

Advances in helper-dependent adenoviral vector research

21 January 2018

1 reference

The influence of innate and pre-existing immunity on adenovirus therapy

21 January 2018

1 reference

Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain

21 January 2018

1 reference

Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro.

21 January 2018

1 reference

Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.

21 January 2018

1 reference

AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method

21 January 2018

1 reference

Molecular evolution of adeno-associated virus for enhanced glial gene delivery

21 January 2018

1 reference

Analysis of neuronal proliferation, migration and differentiation in the postnatal brain using equine infectious anemia virus-based lentiviral vectors

21 January 2018

1 reference

MicroRNAs and the regulation of vector tropism

21 January 2018

1 reference

Characterisation of viral proteins that inhibit Toll-like receptor signal transduction

21 January 2018

1 reference

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

21 January 2018

1 reference

Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1.

21 January 2018

1 reference

Clinical protocol. Gene therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brain

21 January 2018

1 reference

Immune responses to AAV in a phase I study for Canavan disease.

21 January 2018

1 reference

Subthalamic GAD gene therapy in a Parkinson's disease rat model

21 January 2018

1 reference

Increased permeability of blood–brain barrier on the hippocampus of a murine model of senescence

21 January 2018

1 reference

Toll-like receptors in the CNS: implications for neurodegeneration and repair

21 January 2018

1 reference

7 January 2021

New roles for large and small viral RNAs in evading host defences

1 reference

7 January 2021

Inflammatory processes in Alzheimer's disease

1 reference

7 January 2021

Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease.

1 reference

7 January 2021

Identifiers

DOI

10.1038/GT.2010.2

1 reference

Dimensions Publication ID

22 August 2017

1023832523

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