(Q37691187)

English

Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2.

scientific article published on 05 February 2014

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7 March 2020

Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A2 (English)

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7 March 2020

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Kelly J McKelvey

3

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7 March 2020

Christopher B Little

8

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7 March 2020

Christopher J Jackson

10

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7 March 2020

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Meilang Xue

1

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7 March 2020

Kaitlin Shen

2

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7 March 2020

Juan Li

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7 March 2020

Yee-Ka Agnes Chan

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7 March 2020

Vicky Hatzis

6

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7 March 2020

Lyn March

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7 March 2020

Michael Tonkin

9

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7 March 2020

publication date

5 February 2014

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7 March 2020

Arthritis Research and Therapy

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7 March 2020

16

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7 March 2020

1

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7 March 2020

R44

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7 March 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3979138/fullTextXML

based on heuristic

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Soluble endothelial protein C receptor (sEPCR) is likely a biomarker of cancer-associated hypercoagulability in human hematologic malignancies

1 reference

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Endothelial protein C receptor expressed by ovarian cancer cells as a possible biomarker of cancer onset

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23 August 2017

Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma

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23 August 2017

Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well

1 reference

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23 August 2017

Gene discovery in rheumatoid arthritis highlights the CD40/NF-kappaB signaling pathway in disease pathogenesis

1 reference

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23 August 2017

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

1 reference

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23 August 2017

Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction

1 reference

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23 August 2017

In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage

1 reference

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23 August 2017

The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis

1 reference

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23 August 2017

Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes

1 reference

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23 August 2017

Synovial fibroblasts: key players in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979138

23 August 2017

Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo

1 reference

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23 August 2017

Structure and functions of the endothelial cell protein C receptor

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23 August 2017

Pathogenesis of bone and cartilage destruction in rheumatoid arthritis

1 reference

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23 August 2017

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

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Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo

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23 August 2017

Metalloproteolytic release of endothelial cell protein C receptor

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23 August 2017

Mechanisms by which soluble endothelial cell protein C receptor modulates protein C and activated protein C function

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Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor

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23 August 2017

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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Phospholipase A2--a mediator between proximal and distal effectors of inflammation

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The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling.

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Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

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Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

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1 reference

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Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells

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sPLA2-V inhibits EPCR anticoagulant and antiapoptotic properties by accommodating lysophosphatidylcholine or PAF in the hydrophobic groove

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The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis

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EPCR encryption induces cellular APC resistance

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12 December 2020

based on heuristic

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Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: lack of correlation with thrombomodulin suggests involvement of different pathological processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24495480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of secretory group IIa and V phospholipase A2 and cytosolic group IValpha phospholipase A2 in chondrocytes from patients with rheumatoid arthritis

1 reference

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12 December 2020

based on heuristic

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Activated protein C directly activates human endothelial gelatinase A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24495480

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease-activated receptor 2, rather than protease-activated receptor 1, contributes to the aggressive properties of synovial fibroblasts in rheumatoid arthritis

1 reference

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12 December 2020

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Genistein inhibit cytokines or growth factor-induced proliferation and transformation phenotype in fibroblast-like synoviocytes of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24495480

12 December 2020

based on heuristic

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[Detection of soluble endothelial protein C receptor (sEPCR) in patients with CHD, DM and SLE]

1 reference

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12 December 2020

based on heuristic

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Endogenous protein C is essential for the functional integrity of human endothelial cells

1 reference

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12 December 2020

based on heuristic

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IL-1alpha and IL-1beta have different effects on formation and activity of large osteoclasts

1 reference

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Identifiers

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7 March 2020

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7 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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7 March 2020

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