(Q37691483)

22 August 2017

1 reference

title

Iron metabolism in trypanosomatids, and its crucial role in infection (English)

1 reference

22 August 2017

trypanosomatids

1 reference

M C Taylor

1

1 reference

22 August 2017

J M Kelly

series ordinal

2

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22 August 2017

publication date

15 February 2010

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22 August 2017

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22 August 2017

volume

137

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22 August 2017

issue

6

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22 August 2017

page(s)

899-917

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Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologues in trypanosomes

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Heme requirement and intracellular trafficking in Trypanosoma cruzi epimastigotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Role of iron in Trypanosoma cruzi infection of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Hemoglobin receptor in Leishmania is a hexokinase located in the flagellar pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

A cysteine residue near the propionate side chain of heme is the radical site in ascorbate peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Iron chelators modulate the fusogenic properties of Salmonella-containing phagosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The transferrin receptor genes of Trypanosoma equiperdum are less diverse in their transferrin binding site than those of the broad-host range Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Downregulation of the nuclear-encoded subunits of the complexes III and IV disrupts their respective complexes but not complex I in procyclic Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Cloning and characterization of the R1 and R2 subunits of ribonucleotide reductase from Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Detection of a tryptophan radical in the reaction of ascorbate peroxidase with hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Iron-dependent regulation of transferrin receptor expression in Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The significance of transferrin receptor variation in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Crystal structure of human iron regulatory protein 1 as cytosolic aconitase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Endocytosis of gold-labeled proteins and LDL by Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

GPI valence and the fate of secretory membrane proteins in African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The presence of four iron-containing superoxide dismutase isozymes in trypanosomatidae: characterization, subcellular localization, and phylogenetic origin in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Cloning, sequencing and expression of ribonucleotide reductase R2 from Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The efficacy of ascofuranone in a consecutive treatment on Trypanosoma brucei brucei in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Leishmania major ascorbate peroxidase overexpression protects cells against reactive oxygen species-mediated cardiolipin oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Developmental variation in Rab11-dependent trafficking in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosoma cruzi: effect of benznidazole therapy combined with the iron chelator desferrioxamine in infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Transferrin-binding protein complex is the receptor for transferrin uptake in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Glutathione and trypanothione in parasitic hydroperoxide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Regulation of protein trafficking by glycosylphosphatidylinositol valence in African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

ATP generation in the Trypanosoma brucei procyclic form: cytosolic substrate level is essential, but not oxidative phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

In vivo maturation of human frataxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Iron and microbial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosoma brucei: growth differences in different mammalian sera are not due to the species-specificity of transferrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Characterization of the ligand-binding site of the transferrin receptor in Trypanosoma brucei demonstrates a structural relationship with the N-terminal domain of the variant surface glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

A novel heterodimeric transferrin receptor encoded by a pair of VSG expression site-associated genes in T. brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Leishmania chagasi: uptake of iron bound to lactoferrin or transferrin requires an iron reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosome alternative oxidase is regulated post-transcriptionally at the level of RNA stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosome alternative oxidase: from molecule to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The Role of Glutathione Peroxidases in Trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Genetic control of visceral leishmaniasis in a Sudanese population: candidate gene testing indicates a linkage to the NRAMP1 region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Intracellular innate resistance to bacterial pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Growth inhibition of bloodstream forms of Trypanosoma brucei by the iron chelator deferoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Deletion of the Trypanosoma brucei superoxide dismutase gene sodb1 increases sensitivity to nifurtimox and benznidazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Subverted transferrin trafficking in Leishmania-infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Iron Superoxide Dismutases Targeted to the Glycosomes ofLeishmania chagasiAre Important for Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Genetics and visceral leishmaniasis: of mice and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The role of transferrin-receptor variation in the host range of Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

A parasite cysteine protease is key to host protein degradation and iron acquisition

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Bovine trypanotolerance: A natural ability to prevent severe anaemia and haemophagocytic syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosomes change their transferrin receptor expression to allow effective uptake of host transferrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Overexpression of superoxide dismutase in Trypanosoma cruzi results in increased sensitivity to the trypanocidal agents gentian violet and benznidazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The prevention of the growth of Leishmania major progeny in BALB/c iron-loaded mice: a process coupled to increased oxidative burst, the amplitude and duration of which depend on initial parasite developmental stage and dose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

pTcINDEX: a stable tetracycline-regulated expression vector for Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Role of iron homeostasis in trypanosomiasis-associated anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Trypanosoma (Nannomonas) congolense: Changes in respiratory metabolism during the life cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Membrane-bound diiron carboxylate proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The expression level determines the surface distribution of the transferrin receptor in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Factors affecting the level and localization of the transferrin receptor in Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Site-directed mutagenesis reveals the essentiality of the conserved residues in the putative diiron active site of the trypanosome alternative oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Leishmania major encodes an unusual peroxidase that is a close homologue of plant ascorbate peroxidase: a novel role of the transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

SLC11A1 (formerly NRAMP1) and susceptibility to visceral leishmaniasis in The Sudan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

The strange case of Leishmania chagasi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Acute Trypanosoma cruzi infection is associated with anemia, thrombocytopenia, leukopenia, and bone marrow hypoplasia: reversal by nifurtimox treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Immune control of phagosomal bacteria by p47 GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Molecular control of vertebrate iron homeostasis by iron regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Control of iron homeostasis by an iron-regulated ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Knock-downs of Iron-Sulfur Cluster Assembly Proteins IscS and IscU Down-regulate the Active Mitochondrion of ProcyclicTrypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

On the significance of host antibody response to the Trypanosoma brucei transferrin receptor during chronic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Oral and intraperitoneal treatment of Trypanosoma brucei brucei with a combination of ascofuranone and glycerol in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Heme as a source of iron to Leishmania infantum amastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Low affinity of Trypanosoma brucei transferrin receptor to apotransferrin at pH 5 explains the fate of the ligand during endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

Heme metabolism in promastigotes of Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Trypanotolerance, an option for sustainable livestock production in areas at risk from trypanosomosis.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

A transferrin-binding protein of Trypanosoma brucei is encoded by one of the genes in the variant surface glycoprotein gene expression site.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Nramp1 modulates iron homoeostasis in vivo and in vitro: evidence for a role in cellular iron release involving de-acidification of intracellular vesicles

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

A revised model of the active site of alternative oxidase

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Trypanosoma cruzi: treatment with the iron chelator desferrioxamine reduces parasitemia and mortality in experimentally infected mice

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

The outcome of Leishmania major experimental infection in BALB/c mice can be modulated by exogenously delivered iron

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Heme requirement and acquisition by extracellular and intracellular stages of Leishmania mexicana amazonensis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Reduction of dehydroascorbate by trypanothione

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Reconstitution of a surface transferrin binding complex in insect form Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Trypanosoma cruzi receptors for human transferrin and their role

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Mechanism of metalloid-induced death in Leishmania spp.: role of iron, reactive oxygen species, Ca2+, and glutathione

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Is the reactive oxygen species-dependent-NF-kappaB activation observed in iron-loaded BALB/c mice a key process preventing growth of Leishmania major progeny and tissue-damage?

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Transferrin is a growth factor for the bloodstream form ofTrypanosoma brucei

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Bloodstream forms of Trypanosoma brucei require only small amounts of iron for growth

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

Genetic variability in ESAG6 genes among Trypanosoma evansi isolates and in comparison to other Trypanozoon members

1 reference

https://api.crossref.org/works/10.1017%2FS0031182009991880

7 January 2021

10.1017/S0031182009991880

Identifiers

DOI

1 reference

22 August 2017

1 reference