(Q37693601)

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Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases

scientific article published on 07 February 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24508568%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24508568%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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neurodegeneration

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based on heuristic

inferred from title

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7 March 2020

Kelsey M Wanhainen

2

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7 March 2020

Michael J Holtzman

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Michael J Holtzman

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Europe PubMed Central

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7 March 2020

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Britney M Johnson

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7 March 2020

David T Randolph

4

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7 March 2020

Tom J Brett

6

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7 March 2020

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7 February 2014

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7 March 2020

Protein Expression and Purification

1 reference

Europe PubMed Central

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7 March 2020

96

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7 March 2020

32-38

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24508568%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

TREM2 is associated with the risk of Alzheimer's disease in Spanish population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

TREM2 Variants in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Phasercrystallographic software

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

TREM and TREM-like receptors in inflammation and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

The crystal structure of the extracellular domain of the inhibitor receptor expressed on myeloid cells IREM-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

A time- and cost-efficient system for high-level protein production in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Post-crystallization treatments for improving diffraction quality of protein crystals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Crystal structure of the human myeloid cell activating receptor TREM-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Dehydration converts DsbG crystal diffraction from low to high resolution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Macromolecular crystal annealing: evaluation of techniques and variables

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Macromolecular crystal annealing: overcoming increased mosaicity associated with cryocrystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 August 2017

Heterozygous TREM2 mutations in frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

6 September 2017

Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

6 September 2017

Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

6 September 2017

The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

14 September 2017

Glycoprotein structural genomics: solving the glycosylation problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

14 September 2017

Mitigated cytotoxicity and tremendously enhanced gene transfection efficiency of PEI through facile one-step carbamate modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 June 2018

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

23 June 2018

Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

TREM2 R47H variant as a risk factor for early-onset Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

Bacterial sensor triggering receptor expressed on myeloid cells-2 regulates the mucosal inflammatory response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

Characterizing a crystal from an initial native dataset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

Spectacular improvement of X-ray diffraction through fast desiccation of protein crystals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

1 September 2018

TREM2 and neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3980731

3 December 2018

Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A

1 reference

https://pubmed.ncbi.nlm.nih.gov/24508568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/24508568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[34] Rotation function calculations with GLRF program

1 reference

https://pubmed.ncbi.nlm.nih.gov/24508568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A flash-annealing technique to improve diffraction limits and lower mosaicity in crystals of glycerol kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24508568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.PEP.2014.01.015

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24508568%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PMC publication ID

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Europe PubMed Central

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7 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24508568%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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