(Q37694614)

English

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression

scientific article published on 25 October 2016

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scholarly article

1 reference

Europe PubMed Central

22 August 2017

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression (English)

1 reference

Europe PubMed Central

22 August 2017

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Olivier Harismendy

17

object named as

Olivier Harismendy

1 reference

Europe PubMed Central

22 August 2017

Juliann Chmielecki

9

object named as

Juliann Chmielecki

1 reference

Europe PubMed Central

22 August 2017

author name string

Chih-Min Tang

1

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Europe PubMed Central

22 August 2017

Tracy E Lee

2

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Europe PubMed Central

22 August 2017

Sabriya A Syed

3

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Europe PubMed Central

22 August 2017

Adam M Burgoyne

4

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Europe PubMed Central

22 August 2017

Stephanie Y Leonard

5

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Europe PubMed Central

22 August 2017

Fei Gao

6

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Europe PubMed Central

22 August 2017

Jonathan C Chan

7

1 reference

Europe PubMed Central

22 August 2017

Eileen Shi

8

1 reference

Europe PubMed Central

22 August 2017

Deborah Morosini

10

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Europe PubMed Central

22 August 2017

Kai Wang

11

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Europe PubMed Central

22 August 2017

Jeffrey S Ross

12

1 reference

Europe PubMed Central

22 August 2017

Michael L Kendrick

13

1 reference

Europe PubMed Central

22 August 2017

Michael R Bardsley

14

1 reference

Europe PubMed Central

22 August 2017

Martina De Siena

15

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Europe PubMed Central

22 August 2017

Junhao Mao

16

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Europe PubMed Central

22 August 2017

Tamas Ordog

18

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Europe PubMed Central

22 August 2017

Jason K Sicklick

19

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Europe PubMed Central

22 August 2017

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publication date

25 October 2016

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Europe PubMed Central

22 August 2017

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Europe PubMed Central

22 August 2017

7

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Europe PubMed Central

22 August 2017

48

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22 August 2017

78226-78241

1 reference

Europe PubMed Central

22 August 2017

Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRα genotype evaluated by next generation sequencing (NGS)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Targeting Disease Persistence in Gastrointestinal Stromal Tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Stem cells for murine interstitial cells of cajal suppress cellular immunity and colitis via prostaglandin E2 secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Epidemiology of gastrointestinal stromal tumors in the era of histology codes: results of a population-based study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

CTHRC1 acts as a prognostic factor and promotes invasiveness of gastrointestinal stromal tumors by activating Wnt/PCP-Rho signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Anti-tumor effects of the Notch pathway in gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Molecular pathways: the role of primary cilia in cancer progression and therapeutics with a focus on Hedgehog signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Gastrointestinal stromal tumours: origin and molecular oncology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

GLI3 repressor controls functional development of the mouse ureter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Dual and opposing roles of primary cilia in medulloblastoma development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

DNA copy number analysis in gastrointestinal stromal tumors using gene expression microarrays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Progenitors of interstitial cells of cajal in the postnatal murine stomach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Interstitial cells of Cajal in diabetic gastroenteropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Gastrointestinal stromal tumour.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Expressions of sonic hedgehog, patched, smoothened and Gli-1 in human intestinal stromal tumors and their correlation with prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 August 2017

Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

6 September 2017

MAPK inhibitors and siRNAs differentially affect cell death and ROS levels in arsenic trioxide-treated human pulmonary fibroblast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

6 September 2017

Differential gene expression in functional classes of interstitial cells of Cajal in murine small intestine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

6 September 2017

Heat shock protein 90 inhibition in imatinib-resistant gastrointestinal stromal tumor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

14 September 2017

Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

14 September 2017

Conventional and molecular cytogenetic characterization of a new human cell line, GIST-T1, established from gastrointestinal stromal tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

28 September 2017

STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

28 September 2017

Primary cilia in gastric gastrointestinal stromal tumours (GISTs): an ultrastructural study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 June 2018

Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 June 2018

Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

23 June 2018

Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

1 September 2018

A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

1 September 2018

Distinct gene expression-defined classes of gastrointestinal stromal tumor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

1 September 2018

Ultrastructural changes in the interstitial cells of Cajal and gastric dysrhythmias in mice lacking full-length dystrophin (mdx mice).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5346634

1 September 2018

The primary cilium: A relevant characteristic in interstitial cells of rat duodenum enteric plexus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27793025

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary cilia in gastrointestinal stromal tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/27793025

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.12909

1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

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