(Q37700173)

22 August 2017

1 reference

title

Resistance to and synthesis of the antibiotic mupirocin (English)

1 reference

22 August 2017

antibiotic resistance

1 reference

1 reference

Christopher M Thomas

1

1 reference

22 August 2017

Joanne Hothersall

series ordinal

2

1 reference

22 August 2017

Christine L Willis

series ordinal

3

1 reference

22 August 2017

Thomas J Simpson

series ordinal

4

1 reference

22 August 2017

language of work or name

English

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publication date

1 March 2010

1 reference

Nature Reviews Microbiology

22 August 2017

1 reference

22 August 2017

8

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22 August 2017

281-289

1 reference

22 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/nrmicro2278

22 August 2017

0 references

cites work

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Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use.

21 January 2018

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Molecular characterization of the gene encoding high-level mupirocin resistance in Staphylococcus aureus J2870.

21 January 2018

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Mupirocin resistance screening of methicillin-resistant Staphylococcus aureus isolates at Madigan Army Medical Center

21 January 2018

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Antimicrobial activity of mupirocin, daptomycin, linezolid, quinupristin/dalfopristin and tigecycline against vancomycin-resistant enterococci (VRE) from clinical isolates in Korea (1998 and 2005).

21 January 2018

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Quorum-sensing-dependent regulation of biosynthesis of the polyketide antibiotic mupirocin in Pseudomonas fluorescens NCIMB 10586.

21 January 2018

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Pseudomonic Acid: an Antibiotic produced by Pseudomonas fluorescens

21 January 2018

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Isolation of two Pseudomonas strains producing pseudomonic acid A.

31 March 2020

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Pseudomonic acid derivatives from a marine bacterium

31 March 2020

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Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase

31 March 2020

1 reference

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Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Rational design of femtomolar inhibitors of isoleucyl tRNA synthetase from a binding model for pseudomonic acid-A

31 March 2020

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Biochemical basis of mupirocin resistance in strains of Staphylococcus aureus.

31 March 2020

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Mutations affecting the Rossman fold of isoleucyl-tRNA synthetase are correlated with low-level mupirocin resistance in Staphylococcus aureus

31 March 2020

1 reference

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Analysis of mupirocin resistance and fitness in Staphylococcus aureus by molecular genetic and structural modeling techniques

31 March 2020

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Role of RelA of Streptococcus mutans in global control of gene expression

31 March 2020

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Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium.

31 March 2020

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How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense

31 March 2020

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Isolation and identification of bifidobacteriaceae from human saliva

31 March 2020

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Characterization of the mupirocin biosynthesis gene cluster from Pseudomonas fluorescens NCIMB 10586.

31 March 2020

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31 March 2020

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Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals

31 March 2020

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High-level mupirocin resistance within methicillin-resistant Staphylococcus aureus pandemic lineages

31 March 2020

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Detection of methicillin and mupirocin resistance in staphylococcal hospital isolates with a touchdown multiplex polymerase chain reaction

31 March 2020

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Evaluation of disc diffusion methods and Vitek 2 automated system for testing susceptibility to mupirocin in Staphylococcus aureus

31 March 2020

1 reference

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Staphylococcus aureus carrying Panton-Valentine leukocidin genes nasal colonization and skin infection: screening in case of outbreak in a school environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Staphylococcus aureus nasal colonization in preoperative orthopaedic outpatients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Intranasal mupirocin for reduction of Staphylococcus aureus infections in surgical patients with nasal carriage: a systematic review

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

In vitro activity of mupirocin on clinical isolates of Staphylococcus aureus and its potential implications in chronic rhinosinusitis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO2278

Nasal decolonization of Staphylococcus aureus with mupirocin: strengths, weaknesses and future prospects

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO2278

Thematic review series: skin lipids. Antimicrobial lipids at the skin surface

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO2278

Agents for the decolonization of methicillin-resistant Staphylococcus aureus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Pseudomonic acid. Part 2. Biosynthesis of pseudomonic acid A

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRMICRO2278

31 March 2020

https://pubmed.ncbi.nlm.nih.gov/20190824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vivo mutational analysis of the mupirocin gene cluster reveals labile points in the biosynthetic pathway: the "leaky hosepipe" mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Biosynthetic studies on pseudomonic acid (mupirocin), a novel antibiotic metabolite of Pseudomonas fluorescens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Mupirocin H, a novel metabolite resulting from mutation of the HMG-CoA synthase analogue, mupH in Pseudomonas fluorescens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Isoprenoid-like alkylations in polyketide biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Tandemly duplicated acyl carrier proteins, which increase polyketide antibiotic production, can apparently function either in parallel or in series

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Shift to Pseudomonic acid B production in P. fluorescens NCIMB10586 by mutation of mupirocin tailoring genes mupO, mupU, mupV, and macpE.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Mutational analysis reveals that all tailoring region genes are required for production of polyketide antibiotic mupirocin by pseudomonas fluorescens: pseudomonic acid B biosynthesis precedes pseudomonic acid A

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Differentiating the biosynthesis of pseudomonic acids A and B.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Structural and functional characterization of three polyketide synthase gene clusters in Bacillus amyloliquefaciens FZB 42.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Quorum-sensing system influences root colonization and biological control ability in Pseudomonas fluorescens 2P24.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

The chemistry of pseudomonic acid. 17. Dual-action C-1 oxazole derivatives of pseudomonic acid having an extended spectrum of antibacterial activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

The chemistry of pseudomonic acid. 18. Heterocyclic replacement of the alpha,beta-unsaturated ester: synthesis, molecular modeling, and antibacterial activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Synthesis and antibacterial properties of beta-diketone acrylate bioisosteres of pseudomonic acid A

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Enantioselective deprotonation of meso-cycloheptanone derivative: application to the synthesis of a potential intermediate for pseudomonic acid B.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Stereoselective synthesis of methyl monate C

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Recent advances in the preclinical evaluation of the topical antibacterial agent REP8839.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Engineering natural products using combinatorial biosynthesis and biocatalysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Thiomarinols B and C, new antimicrobial antibiotics produced by a marine bacterium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Antimicrobial properties and mode of action of the pyrrothine holomycin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Synthesis and preliminary antibacterial evaluation of simplified thiomarinol analogs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2278

Isoleucyl-tRNA synthetase of Methanobacterium thermoautotrophicum Marburg. Cloning of the gene, nucleotide sequence, and localization of a base change conferring resistance to pseudomonic acid.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20190824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Relationship of protein structure of isoleucyl-tRNA synthetase with pseudomonic acid resistance of Escherichia coli. A proposed mode of action of pseudomonic acid as an inhibitor of isoleucyl-tRNA synthetase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20190824

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRMICRO2278

1 reference

22 August 2017

1 reference