(Q37704997)

22 August 2017

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title

Novel strategy for treatment of pulmonary arterial hypertension: enhancement of apoptosis (English)

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22 August 2017

main subject

arterial hypertension

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author name string

Jing-bin Huang

1

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22 August 2017

Ying-long Liu

2

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22 August 2017

Pei-wu Sun

3

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22 August 2017

Xiao-dong Lv

4

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22 August 2017

Kong Bo

5

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22 August 2017

Xiang-ming Fan

6

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22 August 2017

publication date

6 March 2010

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22 August 2017

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22 August 2017

volume

188

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22 August 2017

issue

3

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22 August 2017

page(s)

179-189

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https://scigraph.springernature.com/pub.10.1007/s00408-010-9233-8

22 August 2017

exact match

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cites work

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1 reference

https://api.crossref.org/works/10.1007%2FS00408-010-9233-8

Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00408-010-9233-8

Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00408-010-9233-8

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00408-010-9233-8

The Role of PPARgamma in pulmonary vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00408-010-9233-8

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

21 January 2018

1 reference

12 December 2020

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

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12 December 2020

Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling

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12 December 2020

Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications

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12 December 2020

Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin

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12 December 2020

Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats

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12 December 2020

Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial

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12 December 2020

Activation of apoptosis signal-regulating kinase 1 in injured artery and its critical role in neointimal hyperplasia

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12 December 2020

New developments in lipid-lowering therapy: the role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase

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12 December 2020

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

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12 December 2020

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

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12 December 2020

Simvastatin enhances bone morphogenetic protein receptor type II expression

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12 December 2020

Peroxisome proliferator-activated receptor-gamma ligands regulate endothelial membrane superoxide production

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12 December 2020

Inhibition of rho kinase attenuates high flow induced pulmonary hypertension in rats.

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12 December 2020

The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension

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12 December 2020

Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats

1 reference

12 December 2020

Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels

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12 December 2020

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

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12 December 2020

Beneficial acute effects of rho-kinase inhibitor in patients with pulmonary arterial hypertension

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12 December 2020

Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase

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12 December 2020

Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms

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12 December 2020

Caspases: enemies within

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12 December 2020

Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis

1 reference

12 December 2020

Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

1 reference

12 December 2020

Acute vasodilator effect of fasudil, a Rho-kinase inhibitor, in monocrotaline-induced pulmonary hypertension in rats

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12 December 2020

The cancer paradigm of severe pulmonary arterial hypertension

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12 December 2020

Treatment of severe pulmonary hypertension: a bradykinin receptor 2 agonist B9972 causes reduction of pulmonary artery pressure and right ventricular hypertrophy.

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12 December 2020

Mitochondria and apoptosis

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12 December 2020

Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

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12 December 2020

Activation of K+ channels: an essential pathway in programmed cell death

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12 December 2020

Emerging therapies for pulmonary arterial hypertension

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12 December 2020

Endothelin-1 and endothelin receptor antagonists in cardiovascular remodeling

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12 December 2020

HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases

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12 December 2020

Sustained membrane depolarization and pulmonary artery smooth muscle cell proliferation.

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12 December 2020

Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth

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12 December 2020

Effects of peroxisome proliferator-activated receptor gamma ligands on monocrotaline-induced pulmonary hypertension in rats

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12 December 2020

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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12 December 2020

Rho kinase in the regulation of cell death and survival

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12 December 2020

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

12 December 2020

Apoptosis: basic mechanisms and implications for cardiovascular disease

1 reference

12 December 2020

Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2

1 reference

12 December 2020

Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c.

1 reference

12 December 2020

The safety of rosiglitazone in the treatment of Type 2 diabetes

1 reference

12 December 2020

Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children

1 reference

12 December 2020

The intrinsic mitochondrial membrane potential of colonic carcinoma cells is linked to the probability of tumor progression

1 reference

12 December 2020

Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C

1 reference

12 December 2020

The PPARgamma ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice.

1 reference

12 December 2020

Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension

1 reference

12 December 2020

Pathogenic mechanisms of pulmonary arterial hypertension

1 reference

12 December 2020

Long-Term Inhibition of Rho-Kinase Suppresses Neointimal Formation After Stent Implantation in Porcine Coronary Arteries: Involvement of Multiple Mechanisms

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12 December 2020

Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells

1 reference

12 December 2020

The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

1 reference

12 December 2020

Effects of hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin on smooth muscle cell proliferation in vitro and neointimal formation in vivo after vascular injury

1 reference

12 December 2020

Long-term inhibition of Rho kinase suppresses intimal thickening in autologous vein grafts in rabbits.

1 reference

12 December 2020

Bcl-2 family members and apoptosis, taken to heart

1 reference

12 December 2020

Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats

1 reference

12 December 2020

Bradykinin B2 receptor as a potential therapeutic target.

1 reference

12 December 2020

Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

1 reference

12 December 2020

Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis

1 reference

12 December 2020

Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats

1 reference

12 December 2020

Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

1 reference

12 December 2020

A primary role for K+ and Na+ efflux in the activation of apoptosis

1 reference

12 December 2020

Attenuated K+ channel gene transcription in primary pulmonary hypertension

1 reference

12 December 2020

Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells

1 reference

12 December 2020

Long-term inhibition of Rho-kinase ameliorates hypoxia-induced pulmonary hypertension in mice

1 reference

12 December 2020

Caspase independent/dependent regulation of K(+), cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis

1 reference

12 December 2020

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms

1 reference

12 December 2020

Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension

1 reference

12 December 2020

The emerging concept of vascular remodeling

1 reference

12 December 2020

The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

1 reference

12 December 2020

Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension

1 reference

12 December 2020

Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis

1 reference

12 December 2020

Bcl-2 decreases voltage-gated K+ channel activity and enhances survival in vascular smooth muscle cells

1 reference

12 December 2020

Inhibitor of apoptosis protein survivin regulates vascular injury.

1 reference

12 December 2020

Physiology of apoptosis

1 reference

12 December 2020

Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation

1 reference

12 December 2020

In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats

1 reference

12 December 2020

Mitochondrial Membrane Potential in Living Cells

1 reference

12 December 2020

Inhibition of serotonin-induced mitogenesis, migration, and ERK MAPK nuclear translocation in vascular smooth muscle cells by atorvastatin

1 reference

12 December 2020

Rho-kinase inhibition reduces neointima formation after vascular injury by enhancing Bax expression and apoptosis.

1 reference

12 December 2020

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

1 reference

12 December 2020

Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.

1 reference

12 December 2020

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

1 reference

12 December 2020

Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor

1 reference

12 December 2020

Validating survivin as a cancer therapeutic target

1 reference

12 December 2020

Cellular and molecular pathobiology of pulmonary arterial hypertension

1 reference

12 December 2020

Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats

1 reference

12 December 2020

Elastase and the pathobiology of unexplained pulmonary hypertension

1 reference

12 December 2020

Differential involvement of initiator caspases in apoptotic volume decrease and potassium efflux during Fas- and UV-induced cell death.

1 reference

12 December 2020

10.1007/S00408-010-9233-8

Identifiers

DOI

1 reference

22 August 2017

1 reference