(Q37705428)

22 August 2017

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title

Systems biology and modeling in neuroblastoma: practicalities and perspectives (English)

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22 August 2017

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Jennifer A Logan

1

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22 August 2017

Martin E Kelly

2

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22 August 2017

Duncan Ayers

3

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22 August 2017

Nicholas Shipillis

4

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22 August 2017

Gerold Baier

5

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22 August 2017

Philip J R Day

6

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22 August 2017

1 March 2010

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

22 August 2017

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22 August 2017

10

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22 August 2017

2

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22 August 2017

131-145

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22 August 2017

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Childhood tumors of the nervous system as disorders of normal development

21 January 2018

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Diversity in neuroblastomas and discrimination of the risk to progress

21 January 2018

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Special pattern of widespread neuroblastoma with a favourable prognosis

21 January 2018

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The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report

21 January 2018

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Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas

21 January 2018

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A systematic review of molecular and biological tumor markers in neuroblastoma

21 January 2018

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The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

21 January 2018

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Outcomes of children with intermediate-risk neuroblastoma after treatment stratified by MYCN status and tumor cell ploidy

21 January 2018

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MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening

21 January 2018

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Mechanism and relevance of ploidy in neuroblastoma

21 January 2018

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Copy number variation at 1q21.1 associated with neuroblastoma

21 January 2018

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Comparison of different techniques for the detection of genetic risk-identifying chromosomal gains and losses in neuroblastoma

21 January 2018

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Biological effects of TrkA and TrkB receptor signaling in neuroblastoma.

21 January 2018

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A comparison of current neuroblastoma chemotherapeutics

21 January 2018

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Molecularly guided therapy of neuroblastoma: a review of different approaches

21 January 2018

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The nature of systems biology

21 January 2018

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Understanding biological functions through molecular networks

21 January 2018

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Systems biology: a brief overview

21 January 2018

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Towards a systems level analysis of health and nutrition

21 January 2018

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Towards a molecular characterisation of pathological pathways.

21 January 2018

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Systems biology: an evolving approach in drug discovery and development

21 January 2018

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Towards drugs targeting multiple proteins in a systems biology approach

21 January 2018

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Network pharmacology: the next paradigm in drug discovery

21 January 2018

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What does systems biology mean for drug development?

21 January 2018

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Systems pathology--or how to solve the complex problem of predictive pathology

21 January 2018

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Global systems biology, personalized medicine and molecular epidemiology

21 January 2018

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Mass spectrometry in systems biology: an overview.

21 January 2018

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Perspectives of DNA microarray and next-generation DNA sequencing technologies

21 January 2018

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Mathematical modeling of intracellular signaling pathways

21 January 2018

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Logic models of pathway biology

21 January 2018

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Gene regulatory network inference: data integration in dynamic models-a review

21 January 2018

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Dynamic modelling and analysis of biochemical networks: mechanism-based models and model-based experiments.

21 January 2018

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"Omics" data and levels of evidence for biomarker discovery

21 January 2018

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Anti-GD2 monoclonal antibody immunotherapy: a promising strategy in the prevention of neuroblastoma relapse

21 January 2018

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Transcriptional regulation and transformation by Myc proteins

21 January 2018

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Computational models of the heart and their use in assessing the actions of drugs

21 January 2018

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Beyond the oncogene paradigm: understanding complexity in cancerogenesis.

21 January 2018

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Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group

21 January 2018

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Retinoid therapy of high-risk neuroblastoma.

21 January 2018

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Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group study

21 January 2018

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Neuroblastoma: biological insights into a clinical enigma

21 January 2018

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The c-Myc target gene network

21 January 2018

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Prognostic value of MYCN and ID2 overexpression in neuroblastoma.

21 January 2018

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Identification of CDK4 as a target of c-MYC.

21 January 2018

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Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

21 January 2018

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Repression of p15INK4b expression by Myc through association with Miz-1

21 January 2018

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Cdc25 cell-cycle phosphatase as a target of c-myc

21 January 2018

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

21 January 2018

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E2F proteins regulate MYCN expression in neuroblastomas

21 January 2018

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Favorable prognostic significance of high-level retinoic acid receptor beta expression in neuroblastoma mediated by effects on cell cycle regulation.

21 January 2018

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4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines

21 January 2018

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Gene and protein expression profiling during differentiation of neuroblastoma cells triggered by 13-cis retinoic acid

21 January 2018

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Retinoic-acid-resistant neuroblastoma cell lines show altered MYC regulation and high sensitivity to fenretinide.

21 January 2018

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Computational modeling of paroxysmal depolarization shifts in neurons induced by the glutamate release from astrocytes

21 January 2018

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Modeling and simulation of genetic regulatory systems: a literature review

21 January 2018

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Systems biology: parameter estimation for biochemical models

21 January 2018

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A primer on learning in Bayesian networks for computational biology

21 January 2018

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Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria

21 January 2018

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A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

21 January 2018

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Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

21 January 2018

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Quantitative inference of dynamic regulatory pathways via microarray data

21 January 2018

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Topography, stem cell behaviour, and organogenesis

21 January 2018

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Feedback loops shape cellular signals in space and time

21 January 2018

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Spatio-temporal protein dynamics in single living cells

21 January 2018

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Keratinocyte-fibroblast interactions in wound healing

21 January 2018

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Communication between neurons and astrocytes: relevance to the modulation of synaptic and network activity

21 January 2018

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Neurophysiology of the neuromuscular junction: overview

21 January 2018

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The adipocyte-myocyte axis in insulin resistance.

21 January 2018

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A tool for the quantitative spatial analysis of complex cellular systems

21 January 2018

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A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap

21 January 2018

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Initial sequencing and analysis of the human genome

21 January 2018

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The International HapMap Project

21 January 2018

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Expression Profiling Using Affymetrix GeneChip Microarrays

21 January 2018

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SuperSAGE: a modern platform for genome-wide quantitative transcript profiling

21 January 2018

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Towards a systems biology understanding of human health: interplay between genotype, environment and nutrition

21 January 2018

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Nutrigenomics and nutrigenetics: the 'omics' revolution in nutritional science

21 January 2018

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The physiology of marriage: pathways to health

21 January 2018

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Explaining human uniqueness: genome interactions with environment, behaviour and culture

21 January 2018

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Health disorders of shift workers

21 January 2018

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Social regulation of gene expression in human leukocytes

21 January 2018

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Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

21 January 2018

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The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

21 January 2018

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Evolving a lingua franca and associated software infrastructure for computational systems biology: the Systems Biology Markup Language (SBML) project

21 January 2018

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The IUPS Physiome Project: a framework for computational physiology

21 January 2018

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Inferring a tumor progression model for neuroblastoma from genomic data

21 January 2018

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Using pharmacokinetic and pharmacodynamic modeling and simulation to evaluate importance of schedule in topotecan therapy for pediatric neuroblastoma

21 January 2018

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A finite mixture survival model to characterize risk groups of neuroblastoma

21 January 2018

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Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group

21 January 2018

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Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERM.10.4

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22 August 2017

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