(Q37709370)

22 August 2017

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title

The endocannabinoid system as a target for the treatment of neuronal damage (English)

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22 August 2017

main subject

endocannabinoid system

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author name string

Javier Fernández-Ruiz

1

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22 August 2017

Concepción García

2

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22 August 2017

Onintza Sagredo

3

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22 August 2017

María Gómez-Ruiz

4

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22 August 2017

Eva de Lago

5

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22 August 2017

language of work or name

English

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publication date

1 April 2010

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Expert Opinion on Therapeutic Targets

22 August 2017

published in

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22 August 2017

volume

14

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22 August 2017

issue

4

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22 August 2017

page(s)

387-404

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The cannabinoid receptor: biochemical, anatomical and behavioral characterization

22 August 2017

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Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Endocannabinoids and the control of energy balance

21 January 2018

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The emerging role of the endocannabinoid system in endocrine regulation and energy balance

21 January 2018

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The endocannabinoid system in targeting inflammatory neurodegenerative diseases

21 January 2018

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Cannabinoids for cancer treatment: progress and promise

21 January 2018

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The endocannabinoid system and neurogenesis in health and disease.

21 January 2018

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Role of cannabinoids and endocannabinoids in cerebral ischemia

21 January 2018

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Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate neurotoxicity.

21 January 2018

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CB1 cannabinoid receptors and on-demand defense against excitotoxicity

21 January 2018

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

21 January 2018

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Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.

21 January 2018

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Cannabinoids and neuroprotection in motor-related disorders

21 January 2018

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The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses

21 January 2018

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Cannabinoids and Parkinson's disease.

21 January 2018

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The endocannabinoid system in Huntington's disease.

21 January 2018

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The endocannabinoid pathway in Huntington's disease: a comparison with other neurodegenerative diseases

21 January 2018

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The endocannabinoid system in amyotrophic lateral sclerosis

21 January 2018

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The endocannabinoid system and multiple sclerosis

21 January 2018

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Endocannabinoids accumulate in spinal cord of SOD1 G93A transgenic mice.

21 January 2018

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Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration

21 January 2018

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Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study

21 January 2018

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Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain.

21 January 2018

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Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.

21 January 2018

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Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.

21 January 2018

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A glial endogenous cannabinoid system is upregulated in the brains of macaques with simian immunodeficiency virus-induced encephalitis.

21 January 2018

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Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down's syndrome

21 January 2018

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21 January 2018

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Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models

21 January 2018

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Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis.

21 January 2018

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COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

21 January 2018

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Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.

21 January 2018

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Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats.

21 January 2018

1 reference

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Cannabinoid CB(2) receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Selective CB2 receptor agonism protects central neurons from remote axotomy-induced apoptosis through the PI3K/Akt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Roles of transient receptor potential vanilloid subtype 1 and cannabinoid type 1 receptors in the brain: neuroprotection versus neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity

21 January 2018

1 reference

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The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Delta 9-tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor.

21 January 2018

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Short-term ischemia usually used for ischemic preconditioning down-regulates central cannabinoid receptors in the gerbil hippocampus

21 January 2018

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Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning

21 January 2018

1 reference

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Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial

21 January 2018

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Role of endocannabinoids and endovanilloids in Ca2+ signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Post-ischemic treatment with cannabidiol prevents electroencephalographic flattening, hyperlocomotion and neuronal injury in gerbils

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

21 January 2018

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Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

21 January 2018

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Cannabidiol--recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Tripartite synapses: astrocytes process and control synaptic information

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728221003709792

Reactive astrocytes in neural repair and protection

21 January 2018

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Glia and their cytokines in progression of neurodegeneration

21 January 2018

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Endocannabinoid signaling in microglial cells

21 January 2018

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Expression and function of the endocannabinoid system in glial cells

21 January 2018

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Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

21 January 2018

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The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728221003709792

Cannabinoids protect astrocytes from ceramide-induced apoptosis through the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

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The seek of neuroprotection: introducing cannabinoids.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728221003709792

The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728221003709792

Cardiovascular effects of cannabinoids

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728221003709792

Cardiovascular actions of cannabinoids and their generation during shock

21 January 2018

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Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors

21 January 2018

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10.1517/14728221003709792

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference