(Q37710809)

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Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations

scientific article published on 24 February 2014

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scholarly article

1 reference

Europe PubMed Central

22 August 2017

Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations (English)

1 reference

Europe PubMed Central

22 August 2017

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

22 August 2017

Payam A Gammage

object named as

Payam A Gammage

1

0 references

Michał Mińczuk

object named as

Michal Minczuk

5

0 references

4

object named as

Edward J Rebar

1 reference

Europe PubMed Central

22 August 2017

author name string

Anna I Vincent

3

1 reference

Europe PubMed Central

22 August 2017

publication date

24 February 2014

1 reference

Europe PubMed Central

22 August 2017

EMBO Molecular Medicine

1 reference

Europe PubMed Central

22 August 2017

6

1 reference

Europe PubMed Central

22 August 2017

4

1 reference

Europe PubMed Central

22 August 2017

458-466

1 reference

Europe PubMed Central

22 August 2017

describes a project that uses

object named as

ImageQuant

2 references

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3992073/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Disease progression in patients with single, large-scale mitochondrial DNA deletions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

New treatments for mitochondrial disease-no time to drop our standards

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease.

1 reference

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23 August 2017

Mitochondrial transformation: time for concerted action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

TEFM (c17orf42) is necessary for transcription of human mtDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Prevalence of mitochondrial DNA disease in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

An improved zinc-finger nuclease architecture for highly specific genome editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Designer zinc-finger proteins and their applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Rapid directional shift of mitochondrial DNA heteroplasmy in animal tissues by a mitochondrially targeted restriction endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

A new mitochondrial disease associated with mitochondrial DNA heteroplasmy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 August 2017

Mitochondrial disorders as windows into an ancient organelle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

6 September 2017

Zinc finger nucleases: looking toward translation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

6 September 2017

The implications of mitochondrial DNA copy number regulation during embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

6 September 2017

Engineered zinc finger proteins for manipulation of the human mitochondrial genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

14 September 2017

Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

14 September 2017

Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

28 September 2017

Bioenergetic consequences of accumulating the common 4977-bp mitochondrial DNA deletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

28 September 2017

Selective inhibition of mutant human mitochondrial DNA replication in vitro by peptide nucleic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

28 September 2017

The nuclear localization signal of NGFI-A is located within the zinc finger DNA binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

23 June 2018

Measurement of the molecular masses of hydrophilic and hydrophobic subunits of ATP synthase and complex I in a single experiment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

1 September 2018

Protein engineering: The fate of fingers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

1 September 2018

Design, construction and in vitro testing of zinc finger nucleases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

1 September 2018

Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992073

1 September 2018

The epidemiology of pathogenic mitochondrial DNA mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/24567072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preassembled zinc-finger arrays for rapid construction of ZFNs

1 reference

https://pubmed.ncbi.nlm.nih.gov/24567072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction and testing of engineered zinc-finger proteins for sequence-specific modification of mtDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/24567072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/EMMM.201303672

1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

1 reference

Europe PubMed Central

22 August 2017

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