(Q37720797)

English

Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties

scientific article published on 20 March 2014

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scholarly article

1 reference

Europe PubMed Central

22 August 2017

Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties (English)

1 reference

Europe PubMed Central

22 August 2017

2

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10 June 2020

Paulo Rodrigues-Santos

3

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10 June 2020

4

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10 June 2020

Edite Teixeira De Lemos

5

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10 June 2020

6

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10 June 2020

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10 June 2020

author name string

Cristina Mega

1

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10 June 2020

Edite Teixeira de Lemos

8

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10 June 2020

publication date

20 March 2014

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Europe PubMed Central

22 August 2017

Diabetology and Metabolic Syndrome

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10 June 2020

6

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10 June 2020

1

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10 June 2020

42

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10 June 2020

https://scigraph.springernature.com/pub.10.1186/1758-5996-6-42

0 references

Dipeptidyl peptidase IV inhibitor attenuates kidney injury in rat remnant kidney

1 reference

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23 August 2017

The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases

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23 August 2017

Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat).

1 reference

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23 August 2017

The interleukin-6 and noradrenaline mediated inflammation-stress feedback mechanism is dysregulated in metabolic syndrome: effect of exercise.

1 reference

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23 August 2017

The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

1 reference

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23 August 2017

Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat)

1 reference

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23 August 2017

Role of IL-1beta in type 2 diabetes

1 reference

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23 August 2017

Control of adipose tissue inflammation through TRB1.

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23 August 2017

Gliptins: a new class of oral antidiabetic agents

1 reference

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23 August 2017

The beta-cell in human type 2 diabetes.

1 reference

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23 August 2017

Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies

1 reference

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23 August 2017

Mammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistance

1 reference

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23 August 2017

Incretin-based therapies: viewpoints on the way to consensus

1 reference

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23 August 2017

Signal transduction mechanism of TRB3 in rats with non-alcoholic fatty liver disease

1 reference

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23 August 2017

Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

TRIB3 functional Q84R polymorphism is a risk factor for metabolic syndrome and carotid atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

The incretin system and its role in type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Incretins: pathophysiological and therapeutic implications of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

The entero-insular axis: implications for human metabolism.

1 reference

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23 August 2017

Type 2 diabetes mellitus: epidemiology, pathophysiology, unmet needs and therapeutical perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Type 2 diabetes: principles of pathogenesis and therapy

1 reference

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23 August 2017

Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans

1 reference

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23 August 2017

Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

1 reference

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23 August 2017

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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23 August 2017

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

1 reference

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23 August 2017

The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 August 2017

The role of TNFalpha and TNF receptors in obesity and insulin resistance

1 reference

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23 August 2017

A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas

1 reference

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23 August 2017

Extra-pancreatic effects of incretin-based therapies

1 reference

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6 September 2017

Renal and cardiac effects of DPP4 inhibitors--from preclinical development to clinical research

1 reference

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6 September 2017

Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes

1 reference

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6 September 2017

The incretin concept today

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

6 September 2017

Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice

1 reference

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14 September 2017

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

14 September 2017

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

14 September 2017

A radical explanation for glucose-induced beta cell dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

14 September 2017

Hyperglycemia-induced production of acute phase reactants in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

28 September 2017

New therapeutic strategies for the treatment of type 2 diabetes mellitus based on incretins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

23 June 2018

Variations in inflammatory biomarkers following the addition of sitagliptin in patients with type 2 diabetes not controlled with metformin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

The dipeptidyl peptidase-4 inhibitor-sitagliptin modulates calcium dysregulation, inflammation, and PPARs in hypertensive cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

A dipeptidyl peptidase-4 inhibitor, sitagliptin, exerts anti-inflammatory effects in type 2 diabetic patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Vildagliptin preserves the mass and function of pancreatic β cells via the developmental regulation and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Both sitagliptin analogue & pioglitazone preserve the beta-cell proportion in the islets with different mechanism in non-obese and obese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Exercise training decreases proinflammatory profile in Zucker diabetic (type 2) fatty rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Overexpression of TRB3 gene in adipose tissue of rats with high fructose-induced metabolic syndrome

1 reference

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1 September 2018

Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

The [pre-] history of the incretin concept

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin

1 reference

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1 September 2018

Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3998187

1 September 2018

Efficacy and safety of sitagliptin when added to ongoing metformin therapy in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1186%2F1758-5996-6-42

21 January 2018

Reduced Incretin Effect in Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1186%2F1758-5996-6-42

21 January 2018

Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

1 reference

https://api.crossref.org/works/10.1186%2F1758-5996-6-42

21 January 2018

Tribbles homologue 3 (TRIB3) and the insulin-resistance genes in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24650557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/24650557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sitagliptin prevents the development of metabolic and hormonal disturbances, increased β-cell apoptosis and liver steatosis induced by a fructose-rich diet in normal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24650557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NEW INTERPRETATION OF ORAL GLUCOSE TOLERANCE

1 reference

https://pubmed.ncbi.nlm.nih.gov/24650557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1758-5996-6-42

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24650557%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24650557%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24650557%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

ResearchGate publication ID

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