(Q37721415)

22 August 2017

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title

Prospects for defined epitope vaccines for respiratory syncytial virus (English)

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22 August 2017

Joanne M Langley

3

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author name string

Robert Anderson

series ordinal

1

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PubMed ID

20353300

22 August 2017

Yan Huang

series ordinal

2

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22 August 2017

1 April 2010

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22 August 2017

18

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based on heuristic

inferred from page(s)

published in

Future Microbiology

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22 August 2017

5

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22 August 2017

4

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22 August 2017

585-602

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Prospects for a respiratory syncytial virus vaccine

22 August 2017

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Increasing incidence of hospitalization for bronchiolitis among Canadian children, 1980-2000.

21 January 2018

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Bronchiolitis-associated hospitalizations among US children, 1980-1996.

21 January 2018

1 reference

Respiratory syncytial virus and T cells: interplay between the virus and the host adaptive immune system

21 January 2018

1 reference

Respiratory syncytial virus immunobiology and pathogenesis

21 January 2018

1 reference

Respiratory syncytial virus: the virus, the disease and the immune response

21 January 2018

1 reference

Immune responses and disease enhancement during respiratory syncytial virus infection

21 January 2018

1 reference

Viral infections, atopy, and asthma: is there a causal relationship?

21 January 2018

1 reference

Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13.

21 January 2018

1 reference

Improved outcome of respiratory syncytial virus infection in a high-risk hospitalized population of Canadian children. Pediatric Investigators Collaborative Network on Infections in Canada

21 January 2018

1 reference

Risk factors for bronchiolitis-associated deaths among infants in the United States

21 January 2018

1 reference

Risk of respiratory syncytial virus infection for infants from low-income families in relationship to age, sex, ethnic group, and maternal antibody level

21 January 2018

1 reference

Immunity to and frequency of reinfection with respiratory syncytial virus

21 January 2018

1 reference

Respiratory-syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children

21 January 2018

1 reference

Respiratory syncytial virus infection in adults

21 January 2018

1 reference

Respiratory syncytial virus infections in previously healthy working adults

21 January 2018

1 reference

Bumps on the vaccine road.

21 January 2018

1 reference

Field evaluation of a respiratory syncytial virus vaccine and a trivalent parainfluenza virus vaccine in a pediatric population

21 January 2018

1 reference

Respiratory virus immunization. I. A field trial of two inactivated respiratory virus vaccines; an aqueous trivalent parainfluenza virus vaccine and an alum-precipitated respiratory syncytial virus vaccine

21 January 2018

1 reference

Vaccines and cytokine-mediated pathology in RSV infection

21 January 2018

1 reference

Pulmonary eosinophilic response to respiratory syncytial virus infection in mice sensitized to the major surface glycoprotein G

21 January 2018

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Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodies

21 January 2018

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Young infants can develop protective levels of neutralizing antibody after infection with respiratory syncytial virus

21 January 2018

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Vaccine-enhanced respiratory syncytial virus disease in cotton rats following immunization with Lot 100 or a newly prepared reference vaccine

21 January 2018

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A role for immune complexes in enhanced respiratory syncytial virus disease

21 January 2018

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Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

21 January 2018

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Fas ligand is required for the development of respiratory syncytial virus vaccine-enhanced disease

21 January 2018

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Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity

21 January 2018

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Role of maternal antibody in pneumonia and bronchiolitis due to respiratory syncytial virus

21 January 2018

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Vaccination with a heterologous respiratory syncytial virus chimeric FG glycoprotein demonstrates significant subgroup cross-reactivity

21 January 2018

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Analysis of the respiratory syncytial virus fusion protein using monoclonal and polyclonal antibodies

21 January 2018

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Biological activity, binding site and affinity of monoclonal antibodies to the fusion protein of respiratory syncytial virus.

21 January 2018

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Plasmid DNA encoding the respiratory syncytial virus G protein is a promising vaccine candidate

21 January 2018

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Vaccination of cotton rats with a chimeric FG glycoprotein of human respiratory syncytial virus induces minimal pulmonary pathology on challenge

21 January 2018

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Immunity and immunopathology to respiratory syncytial virus. The mouse model

21 January 2018

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Cotton rats previously immunized with a chimeric RSV FG glycoprotein develop enhanced pulmonary pathology when infected with RSV, a phenomenon not encountered following immunization with vaccinia--RSV recombinants or RSV.

21 January 2018

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Challenge of BALB/c mice with respiratory syncytial virus does not enhance the Th2 pathway induced after immunization with a recombinant G fusion protein, BBG2NA, in aluminum hydroxide

21 January 2018

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Lack of detectable enhanced pulmonary histopathology in cotton rats immunized with purified F glycoprotein of respiratory syncytial virus (RSV) when challenged at 3-6 months after immunization

21 January 2018

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Second-year surveillance of recipients of a respiratory syncytial virus (RSV) F protein subunit vaccine, PFP-1: evaluation of antibody persistence and possible disease enhancement

21 January 2018

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Respiratory syncytial virus-specific cell-mediated immune responses after vaccination with a purified fusion protein subunit vaccine

21 January 2018

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Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxis

21 January 2018

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Binding and entry of respiratory syncytial virus into host cells and initiation of the innate immune response

21 January 2018

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Enhanced disease and pulmonary eosinophilia associated with formalin-inactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance P

21 January 2018

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CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein

21 January 2018

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Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

21 January 2018

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Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.

21 January 2018

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New strategies for control of respiratory syncytial virus infection

21 January 2018

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The future of respiratory syncytial virus vaccine development

21 January 2018

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Challenges in developing a pediatric RSV vaccine

21 January 2018

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New generation live vaccines against human respiratory syncytial virus designed by reverse genetics

21 January 2018

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Immunoinformatics comes of age

21 January 2018

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Prediction of linear B-cell epitopes.

21 January 2018

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An introduction to epitope prediction methods and software

21 January 2018

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Immune epitope database analysis resource (IEDB-AR).

21 January 2018

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Shifting immunodominance pattern of two cytotoxic T-lymphocyte epitopes in the F glycoprotein of the Long strain of respiratory syncytial virus

21 January 2018

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Human CD8(+) T cell responses against five newly identified respiratory syncytial virus-derived epitopes

21 January 2018

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CD4(+) T cell frequencies and Th1/Th2 cytokine patterns expressed in the acute and memory response to respiratory syncytial virus I-E(d)-restricted peptides.

21 January 2018

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Characterization of the CD8+ T cell responses directed against respiratory syncytial virus during primary and secondary infection in C57BL/6 mice

21 January 2018

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Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection

21 January 2018

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The number of respiratory syncytial virus (RSV)-specific memory CD8 T cells in the lung is critical for their ability to inhibit RSV vaccine-enhanced pulmonary eosinophilia.

21 January 2018

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CD8 T cells inhibit respiratory syncytial virus (RSV) vaccine-enhanced disease.

21 January 2018

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Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus

21 January 2018

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Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus

21 January 2018

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Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

21 January 2018

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Proteolytic activation of respiratory syncytial virus fusion protein. Cleavage at two furin consensus sequences

21 January 2018

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Virus membrane fusion proteins: biological machines that undergo a metamorphosis

21 January 2018

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Respiratory syncytial virus (RSV) fusion protein subunit F2, not attachment protein G, determines the specificity of RSV infection

21 January 2018

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Cytotoxic T cell specificity for respiratory syncytial virus proteins: fusion protein is an important target antigen

21 January 2018

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Visualization and characterization of respiratory syncytial virus F-specific CD8(+) T cells during experimental virus infection

21 January 2018

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Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus

21 January 2018

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Recombinant Sendai virus induces T cell immunity against respiratory syncytial virus that is protective in the absence of antibodies

21 January 2018

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Relevance of viral context and diversity of antigen-processing routes for respiratory syncytial virus cytotoxic T-lymphocyte epitopes

21 January 2018

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Distinct types of lung disease caused by functional subsets of antiviral T cells

21 January 2018

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The cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopes

21 January 2018

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Co-immunization of BALB/c mice with recombinant immunogens containing G protein fragment and chimeric CTL epitope of respiratory syncytial virus induces enhanced cellular immunity and high level of antibody response

21 January 2018

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Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responses

21 January 2018

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Influence of a single viral epitope on T cell response and disease after infection of mice with respiratory syncytial virus

21 January 2018

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Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope

21 January 2018

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Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection

21 January 2018

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Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities

21 January 2018

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Long-lasting balanced immunity and protective efficacy against respiratory syncytial virus in mice induced by a recombinant protein G1F/M2.

21 January 2018

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Nasal delivery of chitosan-DNA plasmid expressing epitopes of respiratory syncytial virus (RSV) induces protective CTL responses in BALB/c mice

21 January 2018

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Viral and host factors in human respiratory syncytial virus pathogenesis

21 January 2018

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Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus

21 January 2018

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The role of IFN in respiratory syncytial virus pathogenesis

21 January 2018

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Eliminating a region of respiratory syncytial virus attachment protein allows induction of protective immunity without vaccine-enhanced lung eosinophilia.

21 January 2018

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Atypical pulmonary eosinophilia is mediated by a specific amino acid sequence of the attachment (G) protein of respiratory syncytial virus

21 January 2018

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The attachment (G) glycoprotein of respiratory syncytial virus contains a single immunodominant epitope that elicits both Th1 and Th2 CD4+ T cell responses.

21 January 2018

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Immune responses to the nonglycosylated ectodomain of respiratory syncytial virus attachment glycoprotein mediate pulmonary eosinophilia in inbred strains of mice with different MHC haplotypes

21 January 2018

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A single amino acid substitution in a recombinant G protein vaccine drastically curtails protective immunity against respiratory syncytial virus (RSV)

21 January 2018

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Modulation of protective immunity, eosinophilia, and cytokine responses by selective mutagenesis of a recombinant G protein vaccine against respiratory syncytial virus

21 January 2018

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Regulation of airway eosinophil and neutrophil infiltration by alpha-galactosylceramide in a mouse model for respiratory syncytial virus (RSV) vaccine-augmented disease

21 January 2018

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Enhanced immune protection by a liposome-encapsulated recombinant respiratory syncytial virus (RSV) vaccine using immunogenic lipids from Deinococcus radiodurans

21 January 2018

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Liposome encapsulation of a soluble recombinant fragment of the respiratory syncytial virus (RSV) G protein enhances immune protection and reduces lung eosinophilia associated with virus challenge

21 January 2018

1 reference

Murine host responses to respiratory syncytial virus (RSV) following intranasal administration of a Protollin-adjuvanted, epitope-enhanced recombinant G protein vaccine

21 January 2018

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Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV

21 January 2018

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Immunopathology in RSV infection is mediated by a discrete oligoclonal subset of antigen-specific CD4(+) T cells.

21 January 2018

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Proliferative expansion and acquisition of effector activity by memory CD4+ T cells in the lungs following pulmonary virus infection

21 January 2018

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Characterization of respiratory syncytial virus M- and M2-specific CD4 T cells in a murine model

21 January 2018

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Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung.

21 January 2018

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Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein

21 January 2018

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HLA class I-restricted cytotoxic T-cell epitopes of the respiratory syncytial virus fusion protein

21 January 2018

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T cell responses to respiratory syncytial virus fusion and attachment proteins in human peripheral blood mononuclear cells

21 January 2018

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Characterization of a novel respiratory syncytial virus-specific human cytotoxic T-lymphocyte epitope

21 January 2018

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Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains

21 January 2018

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Immunological characterization of respiratory syncytial virus N protein epitopes recognized by human cytotoxic T lymphocytes.

21 January 2018

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Identification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells

21 January 2018

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Identification of a common HLA-DP4-restricted T-cell epitope in the conserved region of the respiratory syncytial virus G protein

21 January 2018

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HLA-DP4, the most frequent HLA II molecule, defines a new supertype of peptide-binding specificity

21 January 2018

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Characterization of two antigenic sites recognized by neutralizing monoclonal antibodies directed against the fusion glycoprotein of human respiratory syncytial virus

21 January 2018

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Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein.

21 January 2018

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Expression of the F glycoprotein gene from human respiratory syncytial virus in Escherichia coli: mapping of a fusion inhibiting epitope

21 January 2018

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Mapping of a fusion related epitope of the respiratory syncytial virus fusion protein

21 January 2018

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Use of synthetic peptides to locate neutralizing antigenic domains on the fusion protein of respiratory syncytial virus

21 January 2018

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Binding of neutralizing monoclonal antibodies to regions of the fusion protein of respiratory syncytial virus expressed in Escherichia coli

21 January 2018

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Identification of a synthetic peptide as part of a major neutralization epitope of respiratory syncytial virus

21 January 2018

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Identification of a conserved neutralization site in the first heptad repeat of the fusion protein of respiratory syncytial virus

21 January 2018

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Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein

21 January 2018

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Respiratory syncytial virus recombinant F protein (residues 255-278) induces a helper T cell type 1 immune response in mice

21 January 2018

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Immunogenicity and efficacy of recombinant RSV-F vaccine in a mouse model

21 January 2018

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Characterization of the epitope for anti-human respiratory syncytial virus F protein monoclonal antibody 101F using synthetic peptides and genetic approaches

21 January 2018

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Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres

21 January 2018

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Identification of a Linear Epitope on the Fusion Glycoprotein of Respiratory Syncytial Virus

21 January 2018

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Variable resistance to palivizumab in cotton rats by respiratory syncytial virus mutants

21 January 2018

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Respiratory syncytial virus escape mutant derived in vitro resists palivizumab prophylaxis in cotton rats

21 January 2018

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Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virus

21 January 2018

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Surveillance of clinical isolates of respiratory syncytial virus for palivizumab (Synagis)-resistant mutants

21 January 2018

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Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus

21 January 2018

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Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract

21 January 2018

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Location of the epitope recognized by monoclonal antibody 63G on the primary structure of human respiratory syncytial virus G glycoprotein and the ability of synthetic peptides containing this epitope to induce neutralizing antibodies

21 January 2018

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Subgroup specific protection of mice from respiratory syncytial virus infection with peptides encompassing the amino acid region 174-187 from the G glycoprotein: the role of cysteinyl residues in protection

21 January 2018

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Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein

21 January 2018

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Virus-specific CTL responses induced by an H-2K(d)-restricted, motif-negative 15-mer peptide from the fusion protein of respiratory syncytial virus

21 January 2018

1 reference

Synergistic effect of immunization with a peptide cocktail inducing antibody, helper and cytotoxic T-cell responses on protection against respiratory syncytial virus

21 January 2018

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Monoclonal antibody neutralization escape mutants of respiratory syncytial virus with unique alterations in the attachment (G) protein

21 January 2018

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A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FMB.10.22

1 reference

22 August 2017

1 reference

PubMed ID

20353300