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Liver X receptor (LXR) and the reproductive system--a potential novel target for therapeutic intervention.
scientific article published on January 2010
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Liver X receptor (LXR) and the reproductive system--a potential novel target for therapeutic intervention
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
author
Jerzy Bełtowski
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
Andrzej Semczuk
series ordinal
2
object named as
Andrzej Semczuk
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
publication date
1 January 2010
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
published in
Pharmacological Reports
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
volume
62
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
page(s)
15-27
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
cites work
Liver X receptors (LXR) as therapeutic targets in dyslipidemia
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rediscovery of cerebrosterol.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemical structure of sterols that activate oocyte meiosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cumulus cells of oocyte-cumulus complexes secrete a meiosis-activating substance when stimulated with FSH.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of meiosis activating sterol on in-vitro maturation and fertilization of human oocytes from stimulated and unstimulated ovaries
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver X receptors regulate adrenal cholesterol balance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of human luteal steroidogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of progesterone production in human luteinized granulosa cells treated with LXR agonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LXRs;
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Minireview: liver X receptor beta: emerging roles in physiology and diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human oocyte maturation in vitro is stimulated by meiosis-activating sterol.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Meiosis-activating sterol-mediated resumption of meiosis in mouse oocytes in vitro is influenced by protein synthesis inhibition and cholera toxin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene-gene interaction between heme oxygenase-1 and liver X receptor-beta and Alzheimer's disease risk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride (GW3965).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Soluble endoglin is an accurate predictor and a pathogenic molecule in pre-eclampsia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of rescuing donated immature human oocytes derived after FSH/hCG stimulation following in vitro culture with or without Follicular Fluid Meiosis Activating Sterol (FF-MAS)--an embryo chromosomal and morphological analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Placental expression of the nuclear receptors for oxysterols LXRalpha and LXRbeta during mouse and human development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A synthetic analogue of meiosis-activating sterol (FF-MAS) is a potent agonist promoting meiotic maturation and preimplantation development of mouse oocytes maturing in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxysterol nuclear receptor LXRbeta regulates cholesterol homeostasis and contractile function in mouse uterus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver X receptors regulate adrenal steroidogenesis and hypothalamic-pituitary-adrenal feedback.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol homeostasis and infertility: the liver X receptor connection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plasma 24S-hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipids from oxidized low-density lipoprotein modulate human trophoblast invasion: involvement of nuclear liver X receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol-metabolizing cytochromes P450
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome P450s and cholesterol homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver X receptors and epididymal epithelium physiology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxysterols: modulators of cholesterol metabolism and other processes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of LXRs in control of lipogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrauterine risk factors for precocious atherosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Principal findings from a multicenter trial investigating the safety of follicular-fluid meiosis-activating sterol for in vitro maturation of human cumulus-enclosed oocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced fertility and inability of oocytes to resume meiosis in mice deficient of the Lxr genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: a novel metabolic pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LXR, a nuclear receptor that defines a distinct retinoid response pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous 24(S),25-epoxycholesterol fine-tunes acute control of cellular cholesterol homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970239-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1734-1140(10)70239-5
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
PubMed ID
20360612
1 reference
stated in
Europe PubMed Central
PubMed ID
20360612
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20360612%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 January 2020
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