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A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development.
scientific article published on January 2013
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Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
title
A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
author
Guangan Hu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
author name string
Jianzhu Chen
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2
1 reference
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Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
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English
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publication date
1 January 2013
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Europe PubMed Central
PMCID
3999894
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
published in
Nature Communications
1 reference
stated in
Europe PubMed Central
PMCID
3999894
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
volume
4
1 reference
stated in
Europe PubMed Central
PMCID
3999894
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
page(s)
2830
1 reference
stated in
Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
exact match
https://scigraph.springernature.com/pub.10.1038/ncomms3830
0 references
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Bach2 maintains T cells in a naive state by suppressing effector memory-related genes
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PubMed Central
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Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation
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PubMed Central
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The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets
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23 August 2017
Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells
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23 August 2017
Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1
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Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1
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Transcription factor regulation of CD8+ T-cell memory and exhaustion
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23 August 2017
Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation
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Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
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Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses
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23 August 2017
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties
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Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
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Surviving the crash: transitioning from effector to memory CD8+ T cell
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Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs
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NFATc1 regulates PD-1 expression upon T cell activation.
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23 August 2017
Loss of IL-7R and IL-15R expression is associated with disappearance of memory T cells in respiratory tract following influenza infection
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PubMed Central
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23 August 2017
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection
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PubMed Central
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23 August 2017
Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells
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23 August 2017
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
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PubMed Central
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23 August 2017
Kruppel-like factor 2 regulates thymocyte and T-cell migration
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23 August 2017
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
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Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells
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23 August 2017
Antigen-driven effector CD8 T cell function regulated by T-bet
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23 August 2017
Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin
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23 August 2017
A model T-cell receptor system for studying memory T-cell development
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PubMed Central
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23 August 2017
Protein kinase C(theta) in T cell activation
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PubMed Central
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23 August 2017
Defective T cell activation and autoimmune disorder in Stra13-deficient mice
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23 August 2017
Selecting and maintaining a diverse T-cell repertoire
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23 August 2017
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PubMed Central
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23 August 2017
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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23 August 2017
Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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6 September 2017
Constitutive activation of Wnt signaling favors generation of memory CD8 T cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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23 June 2018
Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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23 June 2018
Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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23 June 2018
Heterogeneous differentiation patterns of individual CD8+ T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
Disparate individual fates compose robust CD8+ T cell immunity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
Different T cell receptor signals determine CD8+ memory versus effector development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
IL-12-programmed long-term CD8+ T cell responses require STAT4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
retrieved
1 September 2018
Transcriptional regulator Id2 mediates CD8+ T cell immunity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
retrieved
1 September 2018
The role of phase II antioxidant enzymes in protecting memory T cells from spontaneous apoptosis in young and old mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
Molecular and functional profiling of memory CD8 T cell differentiation.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
The regulation and function of the Id proteins in lymphocyte development
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
retrieved
1 September 2018
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999894
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1 September 2018
Enforced expression of Runx2 perturbs T cell development at a stage coincident with beta-selection
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/24335726
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A critical role for NF-kappaB transcription factors in the development of CD8+ memory-phenotype T cells
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24335726
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mouse brain organization revealed through direct genome-scale TF expression analysis
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24335726
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24335726
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24335726
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NCOMMS3830
1 reference
stated in
Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
ADS bibcode
2013NatCo...4.2830H
0 references
PMCID
3999894
1 reference
stated in
Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PubMed ID
24335726
1 reference
stated in
Europe PubMed Central
PMCID
3999894
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24335726%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
ResearchGate publication ID
259320586
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