(Q37725293)

22 August 2017

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer (English)

1 reference

22 August 2017

papillary thyroid cancer

1 reference

anaplastic thyroid carcinoma

inferred from title

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

David G McFadden

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Amanda Vernon

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Philip M Santiago

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Raul Martinez-McFaline

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Arjun Bhutkar

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Denise M Crowley

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Martin McMahon

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Tyler Jacks

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

7 April 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

22 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

E1600-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

13 June 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4000830

inferred from PubMed Central ID database lookup

cites work

Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis

1 reference

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Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAF(V600E)-induced thyroid tumors in a mouse model

23 August 2017

1 reference

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Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation

23 August 2017

1 reference

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Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.

23 August 2017

1 reference

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Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

23 August 2017

1 reference

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Late Intervention with anti-BRAFV600E Therapy Induces Tumor Regression in an Orthotopic Mouse Model of Human Anaplastic Thyroid Cancer

23 August 2017

1 reference

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The primary occurrence of BRAF(V600E) is a rare clonal event in papillary thyroid carcinoma.

23 August 2017

1 reference

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Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

23 August 2017

1 reference

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Synergistic Action of a RAF Inhibitor and a Dual PI3K/mTOR Inhibitor in Thyroid Cancer

23 August 2017

1 reference

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Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

23 August 2017

1 reference

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Targeting BRAFV600E with PLX4720 Displays Potent Antimigratory and Anti-invasive Activity in Preclinical Models of Human Thyroid Cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

23 August 2017

1 reference

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Targeting the PI3K signaling pathway in cancer

23 August 2017

1 reference

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Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer

23 August 2017

1 reference

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Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.

23 August 2017

1 reference

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

23 August 2017

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

23 August 2017

1 reference

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Loss of p53 promotes anaplasia and local invasion in ret/PTC1-induced thyroid carcinomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Molecular genetics and diagnosis of thyroid cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Targeted therapies for thyroid tumors.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Improved radioimmunoassay for measurement of mouse thyrotropin in serum: strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Postnatal expression of BRAFV600E does not induce thyroid cancer in mouse models of thyroid papillary carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

BRAF V600E inhibition in anaplastic thyroid cancer.

1 September 2018

1 reference

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BRAF, p53 and SOX2 in anaplastic thyroid carcinoma: evidence for multistep carcinogenesis.

1 September 2018

1 reference

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Association of PTEN gene methylation with genetic alterations in the phosphatidylinositol 3-kinase/AKT signaling pathway in thyroid tumors.

1 September 2018

1 reference

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Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4000830

Thyrocyte-specific expression of Cre recombinase in transgenic mice

1 September 2018

1 reference

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American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1404357111

Phosphatidylinositol 3-kinase/akt and ras/raf-mitogen-activated protein kinase pathway mutations in anaplastic thyroid cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24711431

12 December 2020

inferred from PubMed ID database lookup

Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24711431

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1404357111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

24711431

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24711431%20AND%20SRC:MED&resulttype=core&format=json