(Q33839230)

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Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

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scholarly article

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Europe PubMed Central

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29 July 2017

Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

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Marcella Salzano

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M Salzano

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J A Knauf

1

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Europe PubMed Central

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29 July 2017

M A Sartor

2

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29 July 2017

M Medvedovic

3

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Europe PubMed Central

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29 July 2017

E Lundsmith

4

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Europe PubMed Central

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29 July 2017

M Ryder

5

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Europe PubMed Central

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29 July 2017

Y E Nikiforov

7

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Europe PubMed Central

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29 July 2017

T J Giordano

8

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Europe PubMed Central

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29 July 2017

R A Ghossein

9

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29 July 2017

J A Fagin

10

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29 July 2017

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7 March 2011

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29 July 2017

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29 July 2017

30

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29 July 2017

28

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Europe PubMed Central

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29 July 2017

3153-3162

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Europe PubMed Central

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29 July 2017

describes a project that uses

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Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3136543

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1038/onc.2011.44

0 references

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

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5 July 2018

ConceptGen: a gene set enrichment and gene set relation mapping tool

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5 July 2018

The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer

1 reference

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5 July 2018

The basics of epithelial-mesenchymal transition

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5 July 2018

Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.

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5 July 2018

TGF-beta-induced epithelial to mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Phospho-control of TGF-beta superfamily signaling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

LRpath: a logistic regression approach for identifying enriched biological groups in gene expression data.

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5 July 2018

Regulation of TGF-beta family signaling by E3 ubiquitin ligases

1 reference

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5 July 2018

Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer

1 reference

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5 July 2018

BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

TGFbeta in Cancer

1 reference

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5 July 2018

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Molecular profiling related to poor prognosis in thyroid carcinoma. Combining gene expression data and biological information

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Identification of molecular markers altered during transformation of differentiated into anaplastic thyroid carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

A FoxO-Smad synexpression group in human keratinocytes

1 reference

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5 July 2018

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

BRAF mutation in thyroid cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Identifying differentially expressed genes using false discovery rate controlling procedures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Modulation of Smad2-mediated signaling by extracellular signal-regulated kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Processing of gene expression data generated by quantitative real-time RT-PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

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High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

1 reference

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5 July 2018

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

5 July 2018

Expression of genes in the TGF-beta signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

21 January 2018

Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

21 January 2018

Fast-Find: a novel computational approach to analyzing combinatorial motifs

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

21 January 2018

Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

21 January 2018

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136543

29 October 2018

Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

21 January 2018

TGF-beta-induced apoptosis in human thyrocytes is mediated by p27kip1 reduction and is overridden in neoplastic thyrocytes by NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

31 March 2020

Activation of EGFP expression by Cre-mediated excision in a new ROSA26 reporter mouse strain

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

31 March 2020

The effects of transforming growth factor-beta on growth and differentiation of the continuous rat thyroid follicular cell line, FRTL-5

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https://api.crossref.org/works/10.1038%2FONC.2011.44

31 March 2020

Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression

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https://api.crossref.org/works/10.1038%2FONC.2011.44

31 March 2020

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

31 March 2020

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

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https://api.crossref.org/works/10.1038%2FONC.2011.44

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Effects of transforming growth factor-beta on deoxyribonucleic acid synthesis and iodine metabolism in porcine thyroid cells in culture

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Twisted epithelial-mesenchymal transition blocks senescence

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.44

31 March 2020

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10.1038/ONC.2011.44

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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PMC publication ID

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Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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