(Q37276098)

19 August 2017

1 reference

title

Regulation of TGF-beta family signaling by E3 ubiquitin ligases (English)

1 reference

19 August 2017

Yasumichi Inoue

1

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19 August 2017

Takeshi Imamura

series ordinal

2

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19 August 2017

publication date

18 September 2008

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19 August 2017

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19 August 2017

volume

99

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19 August 2017

issue

11

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19 August 2017

page(s)

2107-2112

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Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

19 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

New insights into TGF-beta-Smad signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smad transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Two major Smad pathways in TGF-beta superfamily signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smad6 inhibits signalling by the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Deadly encounter: ubiquitin meets apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Substrate targeting in the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Ubiquitin ligases: cell-cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Arkadia enhances nodal-related signalling to induce mesendoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Tumor formation by genetic mutations in the components of the Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Regulation of TGF-beta signaling and its roles in progression of tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Inability of transforming growth factor-beta to cause SnoN degradation leads to resistance to transforming growth factor-beta-induced growth arrest in esophageal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

The amplified WWP1 gene is a potential molecular target in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

Patented small molecule inhibitors in the ubiquitin proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00925.X

10.1111/J.1349-7006.2008.00925.X

21 January 2018

Identifiers

DOI

1 reference

release_nlvkoia655bzvbnsrwo5fj76fi

19 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nlvkoia655bzvbnsrwo5fj76fi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference