(Q29617992)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

author name string

Nakayama KI

series ordinal

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

Nakayama K

series ordinal

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

May 2006

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

published in

Nature Reviews Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

volume

6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

page(s)

369-81

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

30 April 2017

issue

5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

30 April 2017

cites work

1 reference

Cyclin is degraded by the ubiquitin pathway

31 March 2020

1 reference

Ubiquitin: Roles in protein modification and breakdown

31 March 2020

1 reference

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

31 March 2020

1 reference

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

31 March 2020

1 reference

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

31 March 2020

1 reference

Regulation of the cell cycle by SCF-type ubiquitin ligases

31 March 2020

1 reference

The anaphase-promoting complex: it's not just for mitosis any more.

31 March 2020

1 reference

The anaphase-promoting complex: a key factor in the regulation of cell cycle

31 March 2020

1 reference

Systematic analysis and nomenclature of mammalian F-box proteins

31 March 2020

1 reference

Cdh1-APC/C, cyclin B-Cdc2, and Alzheimer's disease pathology

31 March 2020

1 reference

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

31 March 2020

1 reference

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

31 March 2020

1 reference

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

31 March 2020

1 reference

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

31 March 2020

1 reference

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

31 March 2020

1 reference

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

31 March 2020

1 reference

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

31 March 2020

1 reference

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

31 March 2020

1 reference

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

31 March 2020

1 reference

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

31 March 2020

1 reference

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

31 March 2020

1 reference

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

31 March 2020

1 reference

Skp2-mediated degradation of p27 regulates progression into mitosis.

31 March 2020

1 reference

Skp2-dependent degradation of p27kip1 is essential for cell cycle progression

31 March 2020

1 reference

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

31 March 2020

1 reference

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

31 March 2020

1 reference

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

31 March 2020

1 reference

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

31 March 2020

1 reference

Amplification and overexpression of SKP2 are associated with metastasis of non-small-cell lung cancers to lymph nodes

31 March 2020

1 reference

Amplification of chromosome 5p correlates with increased expression of Skp2 in HPV-immortalized keratinocytes.

31 March 2020

1 reference

Alterations in the expression of the cell cycle regulatory protein cyclin kinase subunit 1 in colorectal carcinoma.

31 March 2020

1 reference

The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma

31 March 2020

1 reference

Role of the F-box protein Skp2 in lymphomagenesis

31 March 2020

1 reference

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

31 March 2020

1 reference

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

31 March 2020

1 reference

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

31 March 2020

1 reference

Structure and expression of the gene encoding mouse F-box protein, Fwd2.

31 March 2020

1 reference

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase

31 March 2020

1 reference

Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase

31 March 2020

1 reference

Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle

31 March 2020

1 reference

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

31 March 2020

1 reference

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

31 March 2020

1 reference

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

31 March 2020

1 reference

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

31 March 2020

1 reference

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

31 March 2020

1 reference

Deregulated cyclin E induces chromosome instability

31 March 2020

1 reference

Inactivation of hCDC4 can cause chromosomal instability

31 March 2020

1 reference

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

31 March 2020

1 reference

Transcriptional regulation and transformation by Myc proteins

31 March 2020

1 reference

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

31 March 2020

1 reference

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

31 March 2020

1 reference

Skp2 regulates Myc protein stability and activity

31 March 2020

1 reference

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

31 March 2020

1 reference

Multiple niches for Notch in cancer: context is everything

31 March 2020

1 reference

Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.

31 March 2020

1 reference

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

31 March 2020

1 reference

Notch signaling in mammary gland tumorigenesis

31 March 2020

1 reference

Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice

31 March 2020

1 reference

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

31 March 2020

1 reference

The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4).

31 March 2020

1 reference

Molecular targets of the oncogenic transcription factor jun.

31 March 2020

1 reference

A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs

31 March 2020

1 reference

Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity

31 March 2020

1 reference

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP

31 March 2020

1 reference

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

31 March 2020

1 reference

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

31 March 2020

1 reference

Beta-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases

31 March 2020

1 reference

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.

31 March 2020

1 reference

Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

31 March 2020

1 reference

Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene

31 March 2020

1 reference

Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha

31 March 2020

1 reference

APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers

31 March 2020

1 reference

Elevated expression of Wnt antagonists is a common event in hepatoblastomas

31 March 2020

1 reference

Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal Cancer

31 March 2020

1 reference

Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

31 March 2020

1 reference

Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells

31 March 2020

1 reference

Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis

31 March 2020

1 reference

Overexpression of human beta TrCP1 deleted of its F box induces tumorigenesis in transgenic mice

31 March 2020

1 reference

The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

31 March 2020

1 reference

Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

31 March 2020

1 reference

D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p

31 March 2020

1 reference

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

31 March 2020

1 reference

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

31 March 2020

1 reference

Cell cycle mechanisms of sister chromatid separation; roles of Cut1/separin and Cut2/securin

31 March 2020

1 reference

The spindle checkpoint, aneuploidy, and cancer

31 March 2020

1 reference

hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

31 March 2020

1 reference

Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

31 March 2020

1 reference

Securin is required for chromosomal stability in human cells

31 March 2020

1 reference

Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation

31 March 2020

1 reference

Calcium elevation at fertilization coordinates phosphorylation of XErp1/Emi2 by Plx1 and CaMK II to release metaphase arrest by cytostatic factor.

31 March 2020

1 reference

Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells

31 March 2020

1 reference

The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis.

31 March 2020

1 reference

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

31 March 2020

1 reference

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

31 March 2020

1 reference

The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation

31 March 2020

1 reference

Men and sin: what's the difference?

31 March 2020

1 reference

Timing is everything: regulation of mitotic exit and cytokinesis by the MEN and SIN.

31 March 2020

1 reference

The mitotic exit and septation initiation networks

31 March 2020

1 reference

At the interface between signaling and executing anaphase--Cdc14 and the FEAR network

31 March 2020

1 reference

Alterations of anaphase-promoting complex genes in human colon cancer cells

31 March 2020

1 reference

Overexpression of B-type cyclins alters chromosomal segregation

31 March 2020

1 reference

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

31 March 2020

1 reference

Geminin, an inhibitor of DNA replication, is degraded during mitosis

31 March 2020

1 reference

The cellular geography of aurora kinases

31 March 2020

1 reference

Aurora kinases, aneuploidy and cancer, a coincidence or a real link?

31 March 2020

1 reference

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

31 March 2020

1 reference

Amplification/overexpression of a mitotic kinase gene in human bladder cancer

31 March 2020

1 reference

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

31 March 2020

1 reference

Aurora2/BTAK/STK15 is involved in cell cycle checkpoint and cell survival of aggressive non‐Hodgkin's lymphoma

31 March 2020

1 reference

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

31 March 2020

1 reference

Polo-like kinases (Plks) and cancer

31 March 2020

1 reference

The Nek2 protein kinase: a novel regulator of centrosome structure

31 March 2020

1 reference

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

31 March 2020

1 reference

Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies

31 March 2020

1 reference

Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib

31 March 2020

1 reference

Skp2 and Jab1 expression are associated with inverse expression of p27(KIP1) and poor prognosis in oral squamous cell carcinomas

31 March 2020

1 reference

Oropharyngeal cancer pathogenesis: ubiquitin proteolytic, apoptotic and epidermal growth factor related pathways act in concert--first report.

31 March 2020

1 reference

Skp2 is oncogenic and overexpressed in human cancers

31 March 2020

1 reference

Inverse relation between levels of p27(Kip1) and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas

31 March 2020

1 reference

Skp2 overexpression is a p27Kip1-independent predictor of poor prognosis in patients with biliary tract cancers

31 March 2020

1 reference

Skp2 gene copy number aberrations are common in non-small cell lung carcinoma, and its overexpression in tumors with ras mutation is a poor prognostic marker

31 March 2020

1 reference

Immunohistochemical study of Skp2 and Jab1, two key molecules in the degradation of P27, in lung adenocarcinoma

31 March 2020

1 reference

Regulation of p27 by S-phase kinase-associated protein 2 is associated with aggressiveness in non-small-cell lung cancer

31 March 2020

1 reference

Skp2 and p27kip1 expression in melanocytic nevi and melanoma: an inverse relationship

31 March 2020

1 reference

Inverse relationship between p27/Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot

31 March 2020

1 reference

Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas

31 March 2020

1 reference

Biological significance of p27 and Skp2 expression in renal cell carcinoma. A systematic analysis of primary and metastatic tumour tissues using a tissue microarray technique

31 March 2020

1 reference

Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer

31 March 2020

1 reference

Expression of p27 and its ubiquitin ligase subunit Skp2 in upper urinary tract transitional cell carcinoma

31 March 2020

1 reference

Overexpression of Skp2 in carcinoma of the cervix does not correlate inversely with p27 expression

31 March 2020

1 reference

Decreased level of the cell cycle regulator p27 and increased level of its ubiquitin ligase Skp2 in endometrial carcinoma but not in normal secretory or in hyperstimulated endometrium

31 March 2020

1 reference

Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation

31 March 2020

1 reference

Skp2 protein expression in soft tissue sarcomas

31 March 2020

1 reference

S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase

31 March 2020

1 reference

Prognostic significance of the F-box protein Skp2 expression in diffuse large B-cell lymphoma

31 March 2020

1 reference

Elevated S-phase kinase-associated protein 2 protein expression in acute myelogenous leukemia: its association with constitutive phosphorylation of phosphatase and tensin homologue protein and poor prognosis

31 March 2020

1 reference

Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: correlation with p27(Kip1) and proliferation index

31 March 2020

1 reference

Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer

31 March 2020

1 reference

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

31 March 2020

1 reference

Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma

31 March 2020

1 reference

Alterations in cell cycle genes in early stage lung adenocarcinoma identified by expression profiling

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

31 March 2020

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

866463

1030229479

0 references

866463

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16633365

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017