(Q43781438)

26 November 2017

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway (English)

1 reference

26 November 2017

protein ubiquitination

1 reference

based on heuristic

inferred from title

author

Shigetsugu Hatakeyama

5

1 reference

26 November 2017

Hara T

1

1 reference

26 November 2017

Kamura T

2

1 reference

26 November 2017

Nakayama K

3

1 reference

26 November 2017

Oshikawa K

4

1 reference

26 November 2017

Nakayama K

6

1 reference

26 November 2017

language of work or name

English

0 references

publication date

26 October 2001

1 reference

Journal of Biological Chemistry

26 November 2017

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26 November 2017

276

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26 November 2017

48937-48943

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26 November 2017

52

1 reference

Principles of CDK regulation

26 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Themes and variations on ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Structure and expression of the gene encoding mouse F-box protein, Fwd2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

U box proteins as a new family of ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107274200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107274200

1 reference

26 November 2017

1 reference