(Q46229708)

20 December 2017

title

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1. (English)

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20 December 2017

author

Adrian Smith

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ORCID Public Data File 2021

author name string

C Spruck

1

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20 December 2017

H Strohmaier

2

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20 December 2017

M Watson

3

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20 December 2017

A P Smith

4

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20 December 2017

A Ryan

5

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20 December 2017

T W Krek

6

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20 December 2017

S I Reed

7

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20 December 2017

publication date

1 March 2001

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20 December 2017

published in

Molecular Cell

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20 December 2017

volume

7

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20 December 2017

page(s)

639-650

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20 December 2017

issue

3

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20 December 2017

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

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7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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7 January 2021

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

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Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

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7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

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7 January 2021

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

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7 January 2021

The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex

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7 January 2021

The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function

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7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

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7 January 2021

Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets

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7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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7 January 2021

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

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7 January 2021

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

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7 January 2021

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

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7 January 2021

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

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7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

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7 January 2021

Regulation of p34cdc2 protein kinase during mitosis

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7 January 2021

Regulation of the APC and the exit from mitosis

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7 January 2021

Kinetics of Dimerization and Interactions of p13suc1with Cyclin-Dependent Kinases†

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7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

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7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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7 January 2021

Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle control

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7 January 2021

Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosis

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7 January 2021

The xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators

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7 January 2021

Analysis of the Cdc28 protein kinase complex by dosage suppression.

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7 January 2021

Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast

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7 January 2021

Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe

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7 January 2021

Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex

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7 January 2021

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

Role of Suc1 in the activation of the cyclosome by protein kinase Cdk1/cyclin B

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

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7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

The Cdk-associated protein Cks1 functions both in G1 and G2 in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

A mutation in the human cyclin-dependent kinase interacting protein, CksHs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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https://api.crossref.org/works/10.1016%2FS1097-2765%2801%2900210-6

7 January 2021

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

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7 January 2021

10.1016/S1097-2765(01)00210-6

Identifiers

DOI

1 reference

20 December 2017

PubMed ID

11463388

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20 December 2017