(Q43743452)

26 November 2017

title

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase (English)

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26 November 2017

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N P Malek

1

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26 November 2017

H Sundberg

2

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26 November 2017

S McGrew

3

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26 November 2017

K Nakayama

4

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26 November 2017

T R Kyriakides

5

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26 November 2017

J M Roberts

6

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26 November 2017

language of work or name

English

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publication date

1 September 2001

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26 November 2017

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26 November 2017

volume

413

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26 November 2017

issue

6853

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26 November 2017

page(s)

323-327

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Inhibitors of mammalian G1 cyclin-dependent kinases

26 November 2017

cites work

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7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

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7 January 2021

A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells

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7 January 2021

The cyclin-dependent kinase inhibitor p27Kip1 safeguards against inflammatory injury

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7 January 2021

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

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7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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7 January 2021

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

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7 January 2021

Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

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7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

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7 January 2021

A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

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7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

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7 January 2021

Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

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7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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7 January 2021

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

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7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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7 January 2021

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

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7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

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7 January 2021

The ubiquitin-mediated proteolytic pathway as a therapeutic area

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7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

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7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

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7 January 2021

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

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7 January 2021

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

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7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

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7 January 2021

The Cancer Cell and the Cell Cycle Clock

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7 January 2021

A Restriction Point for Control of Normal Animal Cell Proliferation

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7 January 2021

Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.

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7 January 2021

Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene.

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7 January 2021

Identifiers

DOI

10.1038/35095083

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Dimensions Publication ID

26 November 2017

1048869024

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