(Q37727962)

22 August 2017

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title

Three-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity (English)

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22 August 2017

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1 reference

Qin Meng

1

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22 August 2017

language of work or name

English

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publication date

1 June 2010

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Expert Opinion on Drug Metabolism & Toxicology

22 August 2017

published in

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22 August 2017

volume

6

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22 August 2017

issue

6

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22 August 2017

page(s)

733-746

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Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance.

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Cellular imaging predictions of clinical drug-induced liver injury

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425251003674356

Identification and characterization of a novel prespheroid 3-dimensional hepatocyte monolayer on galactosylated substratum.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425251003674356

Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425251003674356

Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425251003674356

Liver cell culture techniques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Liver cell models in in vitro toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Development of a bioartificial liver employing xenogeneic hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Isoniazid-induced hepatotoxicity in rat hepatocytes of gel entrapment culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Clozapine-induced hepatotoxicity in rat hepatocytes by gel entrapment and monolayer culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Regulation of hepatocyte cell cycle progression and differentiation by type I collagen structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Interaction between hepatocytes and collagen gel in hollow fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Use of sandwich-cultured hepatocytes to evaluate impaired bile acid transport as a mechanism of drug-induced hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Characterization of chemically induced hepatotoxicity in collagen sandwiches of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Improved hepatocyte excretory function by immediate presentation of polarity cues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Microfabricated silicon nitride membranes for hepatocyte sandwich culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Long-term culture of adult rat hepatocyte spheroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Cell-based therapy of acute liver failure: the extracorporeal bioartificial liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Rods, tori, and honeycombs: the directed self-assembly of microtissues with prescribed microscale geometries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Hypothermic preservation of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

IGF-I affects glycosaminoglycan/proteoglycan synthesis in breast cancer cells through tyrosine kinase-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Extracorporeal tissue engineered liver-assist devices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Acetaminophen-induced hepatotoxicity of gel entrapped rat hepatocytes in hollow fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Gel entrapment culture of rat hepatocytes for investigation of tetracycline-induced toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Membrane-based PDMS microbioreactor for perfused 3D primary rat hepatocyte cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

A novel 3D mammalian cell perfusion-culture system in microfluidic channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Toxicological implications of hepatobiliary transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

A comparison of hepatocyte cytotoxic mechanisms for chromate and arsenite

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Enterohepatic transport of bile salts and genetics of cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. II. Spheroid cell spreading inhibition as a new cytotoxic marker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Differential methotrexate hepatotoxicity on rat hepatocytes in 2-D monolayer culture and 3-D gel entrapment culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Sensitivities of gel entrapped hepatocytes in hollow fibers to hepatotoxic drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Re-evaluation of tacrine hepatotoxicity using gel entrapped hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Investigation of rifampicin-induced hepatotoxicity in rat hepatocytes maintained in gel entrapment culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Hepatotoxicity of anti-inflammatory and analgesic drugs: ultrastructural aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Probing enhanced cytochrome P450 2B1/2 activity in rat hepatocyte spheroids through confocal laser scanning microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

In vivo hepatotoxicity study of rats in comparison with in vitro hepatotoxicity screening system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Tetracycline-induced steatosis in primary canine hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Isolated hepatocytes: use in experimental and clinical hepatology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Concordance of the toxicity of pharmaceuticals in humans and in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Species-specific differences in coumarin-induced hepatotoxicity as an example toxicogenomics-based approach to assessing risk of toxicity to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Rifampicin exacerbates isoniazid-induced toxicity in human but not in rat hepatocytes in tissue-like cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Current concepts of mechanisms in drug-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Viability assessment in sandwich-cultured rat hepatocytes after xenobiotic exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Cytochrome P450 activity in control and induced long-term cultures of rat hepatocyte spheroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

A microfluidic 3D hepatocyte chip for drug toxicity testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Culture of primary rat hepatocytes within porous chitosan scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Growth factors and nonparenchymal cell conditioned media induce mitogenic responses in stable long-term adult rat hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

Azathioprine hepatotoxicity and the protective effect of liquorice and glycyrrhizic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425251003674356

10.1517/17425251003674356

21 January 2018

Identifiers

DOI

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22 August 2017

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