(Q37727994)

22 August 2017

1 reference

title

Antibody effector mechanisms in myasthenia gravis-pathogenesis at the neuromuscular junction (English)

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22 August 2017

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1 reference

neuromuscular junction

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Mario Losen

12

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author name string

Alejandro M Gomez

1

1 reference

22 August 2017

Joost Van Den Broeck

2

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22 August 2017

Kathleen Vrolix

3

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22 August 2017

Sofie P Janssen

4

1 reference

22 August 2017

Marijke A M Lemmens

5

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22 August 2017

Eline Van Der Esch

6

1 reference

22 August 2017

Hans Duimel

7

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22 August 2017

Peter Frederik

8

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22 August 2017

Peter C Molenaar

9

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22 August 2017

Pilar Martínez-Martínez

10

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22 August 2017

Marc H De Baets

11

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22 August 2017

1 August 2010

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22 August 2017

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22 August 2017

43

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22 August 2017

5-6

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22 August 2017

353-370

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Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value

22 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Clinical correlates with anti-MuSK antibodies in generalized seronegative myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Immunosuppressive therapies in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The auto-antigen repertoire in myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Thymoma and paraneoplastic myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Spontaneous production of anti-IFN-alpha and anti-IL-12 autoantibodies by thymoma cells from myasthenia gravis patients suggests autoimmunization in the tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Thymic remodeling associated with hyperplasia in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Striational antibodies in myasthenia gravis: reactivity and possible clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Neuromuscular junction autoimmune disease: muscle specific kinase antibodies and treatments for myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Diagnostic use of autoantibodies in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Acetylcholine receptor: an allosteric protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Safety factor at the neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Targeting transcription to the neuromuscular synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Induction of acetylcholine receptors on cultured skeletal muscle by a factor extracted from brain and spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Spatial and temporal expression of acetylcholine receptor RNAs in innervated and denervated rat soleus muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Agrin acts via a MuSK receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Rapsyn and agrin slow the metabolic degradation of the acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Acetylcholine in Intercostal Muscle from Myasthenia Gravis Patients and in Rat Diaphragm after Blockade of Acetylcholine Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Are MuSK antibodies the primary cause of myasthenic symptoms?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Detection and characterization of MuSK antibodies in seronegative myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

MuSK-antibody positive myasthenia gravis: clinical and electrodiagnostic patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Single-fiber electromyography in limb and facial muscles in muscle-specific kinase antibody and acetylcholine receptor antibody myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The differential ability of human IgG1 and IgG4 to activate complement is determined by the COOH-terminal sequence of the CH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Influence of the hinge region on complement activation, C1q binding, and segmental flexibility in chimeric human immunoglobulins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Long-term effects of repeated plasma exchange in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Major pathogenic effects of anti-MuSK antibodies in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

A single amino acid substitution abolishes the heterogeneity of chimeric mouse/human (IgG4) antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Myasthenic immunoglobulin accelerates acetylcholine receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The membrane attack complex of complement at the endplate in myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Treatment of myasthenia gravis by preventing acetylcholine receptor modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Role of complement in the pathogenesis of experimental autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Overexpression of rapsyn in rat muscle increases acetylcholine receptor levels in chronic experimental autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Anti-acetylcholine receptor antibodies directed against the alpha-bungarotoxin binding site induce a unique form of experimental myasthenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Utrophin abundance is reduced at neuromuscular junctions of patients with both inherited and acquired acetylcholine receptor deficiencies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Current understanding of congenital myasthenic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The congenital myasthenic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The muscle protein Dok-7 is essential for neuromuscular synaptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

MUSK, a new target for mutations causing congenital myasthenic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Dok-7 mutations underlie a neuromuscular junction synaptopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Mutations in LAMB2 causing a severe form of synaptic congenital myasthenic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Primary structure of dystrophin-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Is dystrophin present in the nerve terminal at the neuromuscular junction? An immunohistochemical study of the heterozygote dystrophic (mdx) mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Clustering and immobilization of acetylcholine receptors by the 43-kD protein: a possible role for dystrophin-related protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Subtle neuromuscular defects in utrophin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Neural agrin increases postsynaptic ACh receptor packing by elevating rapsyn protein at the mouse neuromuscular synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Lrp4 is a receptor for Agrin and forms a complex with MuSK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Increased ratio of rapsyn to ACh receptor stabilizes postsynaptic receptors at the mouse neuromuscular synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Synapse disassembly and formation of new synapses in postnatal muscle upon conditional inactivation of MuSK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Interaction of LDL receptor-related protein 4 (LRP4) with postsynaptic scaffold proteins via its C-terminal PDZ domain-binding motif, and its regulation by Ca/calmodulin-dependent protein kinase II

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

LRP4 serves as a coreceptor of agrin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Molecular basis of distinct interactions between Dok1 PTB domain and tyrosine-phosphorylated EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

A mammalian homolog of Drosophila tumorous imaginal discs, Tid1, mediates agrin signaling at the neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

A mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

HTLV-1 Tax-associated hTid-1, a human DnaJ protein, is a repressor of Ikappa B kinase beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

New dogs in the dogma: Lrp4 and Tid1 in neuromuscular synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Genomic organization and expression of the human tumorous imaginal disc (TID1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Schizosaccharomyces pombeRdh54 (TID1) Acts with Rhp54 (RAD54) to Repair Meiotic Double-Strand Breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Functional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

hTid-1, a human DnaJ protein, modulates the interferon signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Induction of myasthenia by immunization against muscle-specific kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Myasthenia gravis induced in mice by immunization with the recombinant extracellular domain of rat muscle-specific kinase (MuSK).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

The effect of plasma from muscle-specific tyrosine kinase myasthenia patients on regenerating endplates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Development of novel therapies for MG: Studies in animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Autoimmune Response to Acetylcholine Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Experimental myasthenia gravis. A murine system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

CD4+ T cells and cytokines in the pathogenesis of acquired myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Interferon gamma (IFN-gamma) is necessary for the genesis of acetylcholine receptor-induced clinical experimental autoimmune myasthenia gravis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Absence of IL-4 facilitates the development of chronic autoimmune myasthenia gravis in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Myasthenia gravis as a prototype autoimmune receptor disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Identification of a hexapeptide that mimics a conformation-dependent binding site of acetylcholine receptor by use of a phage-epitope library

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Effector mechanisms in myasthenia gravis: end-plate function after passive transfer of IgG, Fab, and F(ab')2 hybrid molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Recent approaches to the development of antigen-specific immunotherapies for myasthenia gravis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Passively transferred myasthenia gravis: protection of mouse endplates by Fab fragments from human myasthenic IgG

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Anti-acetylcholine receptor antibodies in neonatal myasthenia gravis: heterogeneity and pathogenic significance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Transient neonatal myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Association of neonatal myasthenia gravis with antibodies against the fetal acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Acquired myasthenia gravis: what we have learned from experimental and spontaneous animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine recepotr antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Severe neonatal myasthenia due to maternal anti-MuSK antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

A transient neonatal myasthenic syndrome with anti-musk antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Accessibility control and machinery of immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Interleukin 10 aggravates experimental autoimmune myasthenia gravis through inducing Th2 and B cell responses to AChR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Anti-MuSK-positive myasthenia gravis: neuromuscular transmission failure in facial and limb muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

Experimental autoimmune myasthenia induced in monkeys by purified acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916930903555943

10.3109/08916930903555943

21 January 2018

Identifiers

DOI

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release_eabcmhyyufccth2tkjb62sbwly

22 August 2017

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https://api.fatcat.wiki/v0/release/eabcmhyyufccth2tkjb62sbwly

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference