(Q37738138)

22 August 2017

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title

The genetics of pediatric brain tumors (English)

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22 August 2017

Stefan Pfister

5

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Paul A Northcott

series ordinal

2

object named as

Paul A Northcott

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22 August 2017

6

Michael D Taylor

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22 August 2017

1

Adrian M Dubuc

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22 August 2017

3

Stephen Mack

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22 August 2017

Hendrik Witt

4

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22 August 2017

publication date

1 May 2010

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Current Neurology and Neuroscience Reports

22 August 2017

published in

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22 August 2017

volume

10

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22 August 2017

issue

3

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22 August 2017

page(s)

215-223

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https://scigraph.springernature.com/pub.10.1007/s11910-010-0103-9

22 August 2017

exact match

0 references

cites work

Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis.

1 reference

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https://api.crossref.org/works/10.1007%2FS11910-010-0103-9

Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11910-010-0103-9

Epigenetic events in medulloblastoma development.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11910-010-0103-9

Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.

21 January 2018

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12 December 2020

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

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Medulloblastoma: developmental mechanisms out of control

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A clinicobiological model predicting survival in medulloblastoma.

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Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor

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Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics.

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12 December 2020

Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas.

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12 December 2020

Genome-epigenome interactions in cancer

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12 December 2020

Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin.

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12 December 2020

Genomic analysis of pilocytic astrocytomas at 0.97 Mb resolution shows an increasing tendency toward chromosomal copy number change with age.

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12 December 2020

Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors

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12 December 2020

Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma

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12 December 2020

Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients

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12 December 2020

High promoter hypermethylation frequency of p14/ARF in supratentorial PNET but not in medulloblastoma

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12 December 2020

Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene

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Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

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The genetic and epigenetic basis of ependymoma.

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12 December 2020

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

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12 December 2020

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

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12 December 2020

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

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12 December 2020

Molecular insight into medulloblastoma and central nervous system primitive neuroectodermal tumor biology from hereditary syndromes: a review

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Molecular genetic analysis of the TP53, PTEN, CDKN2A, EGFR, CDK4 and MDM2 tumour-associated genes in supratentorial primitive neuroectodermal tumours and glioblastomas of childhood.

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Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

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Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2

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Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

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12 December 2020

Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood

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High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors.

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The molecular basis of Turcot's syndrome

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Radial glia cells are candidate stem cells of ependymoma

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Analysis of pilocytic astrocytoma by comparative genomic hybridization.

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Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

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Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

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Medulloblastoma in childhood: new biological advances

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The origins of medulloblastoma subtypes

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Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system.

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Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

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The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

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12 December 2020

Prediction of central nervous system embryonal tumour outcome based on gene expression

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12 December 2020

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

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12 December 2020

An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma

1 reference

12 December 2020

Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma

1 reference

12 December 2020

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

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12 December 2020

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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12 December 2020

RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma

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12 December 2020

Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

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12 December 2020

The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors

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12 December 2020

Outcome for children with supratentorial primitive neuroectodermal tumors treated with surgery, radiation, and chemotherapy

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12 December 2020

Optic pathway gliomas in neurofibromatosis-1: controversies and recommendations.

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12 December 2020

Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.

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12 December 2020

Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma

1 reference

12 December 2020

10.1007/S11910-010-0103-9

Identifiers

DOI

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22 August 2017

1 reference