(Q37753116)

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NEXT1 PEST domain mutants are cleaved to produce NICD1 PEST domain mutants

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2220988)

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8 July 2022

Constitutive Signaling by NOTCH1 PEST Domain Mutants

1 reference

8 July 2022

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-2220988

1 reference

8 July 2022

NEXT1 PEST domain mutants [plasma membrane]

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1 reference

8 July 2022

NICD1 PEST Domain Mutants [cytosol]

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8 July 2022

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8 July 2022

gamma-secretase complex [plasma membrane]

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1 reference

8 July 2022

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1 reference

8 July 2022

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

1 reference

8 July 2022

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

1 reference

8 July 2022

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

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8 July 2022

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q37753116)

NEXT1 PEST domain mutants are cleaved to produce NICD1 PEST domain mutants

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