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NOTCH1 PEST domain mutants stimulate MYC transcription
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2220985)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
part of
Constitutive Signaling by NOTCH1 PEST Domain Mutants
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
exact match
https://identifiers.org/reactome:R-HSA-2220985
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
has part(s)
MYC proto-oncogene, bHLH transcription factor
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
NOTCH1 PEST Domain Mutants Coactivator Complex:MYC Gene [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
cites work
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
Identifiers
Reactome ID
R-HSA-2220985
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220985
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