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NOTCH1 PEST domain mutants coactivator complex binds CDK8:CCNC
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2220957)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
part of
Constitutive Signaling by NOTCH1 PEST Domain Mutants
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
exact match
https://identifiers.org/reactome:R-HSA-2220957
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
has part(s)
CDK8:CCNC [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
cites work
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
Identifiers
Reactome ID
R-HSA-2220957
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2220957
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